8UWF

NMR structure of the funnel-web spider toxin Hc3a

Summary for 8UWF

• Entry DOI: 10.2210/pdb8uwf/pdb
• NMR Information: BMRB: 31124
• Descriptor: Pi-Hexatoxin-Hc1b_1 (1 entity in total)
• Functional Keywords: inhibitor cystine knot, acid-sensing ion channel, toxin
• Biological source: Hadronyche cerberea
• Total number of polymer chains: 1
• Total formula weight: 4495.24

Authors

Budusan, E.,Payne, C.D.,Gonzalez, T.I.,Clark, R.J.,Rosengren, K.J.,Rash, L.D.,Cristofori-Armstrong, B. (deposition date: 2023-11-06, release date: 2024-03-13, Last modification date: 2024-04-10)

• Primary citation: Budusan, E.,Payne, C.D.,Gonzalez, T.I.,Obergrussberger, A.,Becker, N.,Clark, R.J.,Johan Rosengren, K.,Rash, L.D.,Cristofori-Armstrong, B.; The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation.; Biochem Pharmacol, :116175-116175, 2024; PubMed: 38552850; DOI: 10.1016/j.bcp.2024.116175

Experimental method

SOLUTION NMR