3VYB
 
 | | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/hmCG sequence | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5HC)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... | | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2012-09-22 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
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3VXX
 | | Crystal structure of methyl CpG binding domain of MBD4 in complex with the 5mCG/5mCG sequence | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*GP*TP*CP*(5CM)P*GP*GP*TP*AP*GP*TP*GP*AP*CP*T)-3'), ... | | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2012-09-21 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
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5NEV
 | | CDK2/Cyclin A in complex with compound 73 | | 分子名称: | 4-[[6-(3-phenylphenyl)-7~{H}-purin-2-yl]amino]benzenesulfonamide, Cyclin-A2, Cyclin-dependent kinase 2 | | 著者 | Coxon, C.R, Anscombe, E, Harnor, S.J, Martin, M.P, Carbain, B, Hardcastle, I.R, Harlow, L.K, Korolchuk, S, Matheson, C.J, Noble, M.E.M, Newell, D.R, Turner, D, Sivaprakasam, M, Wang, L.Z, Wong, C, Golding, B.T, Griffin, R.J, Cano, G. | | 登録日 | 2017-03-12 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines.
J. Med. Chem., 60, 2017
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1XPA
 | | SOLUTION STRUCTURE OF THE DNA-AND RPA-BINDING DOMAIN OF THE HUMAN REPAIR FACTOR XPA, NMR, 1 STRUCTURE | | 分子名称: | XPA, ZINC ION | | 著者 | Ikegami, T, Kuraoka, I, Saijo, M, Kodo, N, Kyogoku, Y, Morikawa, K, Tanaka, K, Shirakawa, M. | | 登録日 | 1998-07-06 | | 公開日 | 1999-07-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the DNA- and RPA-binding domain of the human repair factor XPA.
Nat.Struct.Biol., 5, 1998
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3VYQ
 | | Crystal structure of the methyl CpG Binding Domain of MBD4 in complex with the 5mCG/TG sequence in space group P1 | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*AP*CP*AP*TP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*TP*GP*GP*AP*TP*GP*T)-3'), ... | | 著者 | Otani, J, Arita, K, Kato, T, Kinoshita, M, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2012-10-02 | | 公開日 | 2013-01-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.525 Å) | | 主引用文献 | Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
J.Biol.Chem., 288, 2013
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2LMK
 | | Solution Structure of Mouse Pheromone ESP1 | | 分子名称: | Exocrine gland-secreting peptide 1 | | 著者 | Yoshinaga, S, Sato, T, Hirakane, M, Esaki, K, Hamaguchi, T, Haga-Yamanaka, S, Tsunoda, M, Kimoto, H, Shimada, I, Touhara, K, Terasawa, H. | | 登録日 | 2011-12-06 | | 公開日 | 2013-04-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Mouse Sex Peptide Pheromone ESP1 Reveals a Molecular Basis for Specific Binding to the Class-C G-Protein-Coupled Vomeronasal Receptor
J.Biol.Chem., 2013
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1UGL
 | | Solution structure of S8-SP11 | | 分子名称: | S-locus pollen protein | | 著者 | Mishima, M, Takayama, S, Sasaki, K, Jee, J.G, Kojima, C, Isogai, A, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-06-16 | | 公開日 | 2003-09-30 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Male Determinant Factor for Brassica Self-incompatibility
J.Biol.Chem., 278, 2003
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3ASK
 | | Structure of UHRF1 in complex with histone tail | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ZINC ION | | 著者 | Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2010-12-16 | | 公開日 | 2012-01-25 | | 最終更新日 | 2013-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.904 Å) | | 主引用文献 | Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Proc.Natl.Acad.Sci.USA, 109, 2012
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3ASL
 | | Structure of UHRF1 in complex with histone tail | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ... | | 著者 | Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M. | | 登録日 | 2010-12-16 | | 公開日 | 2012-01-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Proc.Natl.Acad.Sci.USA, 109, 2012
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1YM4
 | | Crystal structure of human beta secretase complexed with NVP-AMK640 | | 分子名称: | Beta-secretase 1, NVP-AMK640 INHIBITOR | | 著者 | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | | 登録日 | 2005-01-20 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics
J.Med.Chem., 48, 2005
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1YM2
 | | Crystal structure of human beta secretase complexed with NVP-AUR200 | | 分子名称: | Beta-secretase 1, NVP-AUR200 INHIBITOR | | 著者 | Hanessian, S, Yun, H, Hou, Y, Yang, G, Bayrakdarian, M, Therrien, E, Moitessier, N, Roggo, S, Veenstra, S. | | 登録日 | 2005-01-20 | | 公開日 | 2006-01-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics
J.Med.Chem., 48, 2005
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6YN0
 | | Structure of E. coli PBP1b with a FtsN peptide activating transglycosylase activity | | 分子名称: | Cell division protein FtsN, MOENOMYCIN, Penicillin-binding protein 1B | | 著者 | Kerff, F, Terrak, M, Boes, A, Herman, H, Charlier, P. | | 登録日 | 2020-04-10 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The bacterial cell division protein fragment E FtsN binds to and activates the major peptidoglycan synthase PBP1b.
J.Biol.Chem., 295, 2020
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1B9O
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2MGW
 | | Solution Structure of the UBA Domain of Human NBR1 | | 分子名称: | Next to BRCA1 gene 1 protein | | 著者 | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | | 登録日 | 2013-11-09 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.
J.Biol.Chem., 289, 2014
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2RRE
 | | Structure and function of the N-terminal nucleolin binding domain of nuclear valocine containing protein like 2 (NVL2) harboring a nucleolar localization signal | | 分子名称: | Putative uncharacterized protein | | 著者 | Fujiwara, Y, Fujiwara, K, Goda, N, Iwaya, N, Tenno, T, Shirakawa, M, Hiroaki, H. | | 登録日 | 2010-08-03 | | 公開日 | 2011-04-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and function of the N-terminal nucleolin binding domain of nuclear valosin-containing protein-like 2 (NVL2) harboring a nucleolar localization signal
J.Biol.Chem., 286, 2011
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2MJ5
 | | Structure of the UBA Domain of Human NBR1 in Complex with Ubiquitin | | 分子名称: | Next to BRCA1 gene 1 protein, Polyubiquitin-C | | 著者 | Walinda, E, Morimoto, D, Sugase, K, Komatsu, M, Tochio, H, Shirakawa, M. | | 登録日 | 2013-12-25 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the ubiquitin-associated (UBA) domain of human autophagy receptor NBR1 and its interaction with ubiquitin and polyubiquitin.
J.Biol.Chem., 289, 2014
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7CJV
 | | Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a dilute environment | | 分子名称: | Monomeric Human Cu,Zn Superoxide dismutase | | 著者 | Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K. | | 登録日 | 2020-07-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel.
J.Phys.Chem.B, 125, 2021
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7D8K
 | | Solution structure of the methyl-CpG binding domain of MBD6 from Arabidopsis thaliana | | 分子名称: | Methyl-CpG-binding domain-containing protein 6 | | 著者 | Mahana, Y, Ohki, I, Walinda, E, Morimoto, D, Sugase, K, Shirakawa, M. | | 登録日 | 2020-10-08 | | 公開日 | 2021-10-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Insights into Methylated DNA Recognition by the Methyl-CpG Binding Domain of MBD6 from Arabidopsis thaliana .
Acs Omega, 7, 2022
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3W6I
 | | Crystal structure of 19F probe-labeled hCAI | | 分子名称: | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, Carbonic anhydrase 1, ZINC ION | | 著者 | Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I. | | 登録日 | 2013-02-14 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.693 Å) | | 主引用文献 | Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR
To be published
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7CJW
 | | Solution structure of monomeric superoxide dismutase 1 with an additional mutation H46W in a crowded environment | | 分子名称: | Monomeric Human Cu,Zn Superoxide dismutase | | 著者 | Iwakawa, N, Morimoto, D, Walinda, E, Danielsson, J, Shirakawa, M, Sugase, K. | | 登録日 | 2020-07-14 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Transient Diffusive Interactions with a Protein Crowder Affect Aggregation Processes of Superoxide Dismutase 1 beta-Barrel.
J.Phys.Chem.B, 125, 2021
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3WO2
 | | Crystal structure of human interleukin-18 | | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Interleukin-18, SULFATE ION | | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | | 登録日 | 2013-12-19 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
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3WO4
 | | Crystal structure of the IL-18 signaling ternary complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | | 登録日 | 2013-12-19 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
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2EI9
 | | Crystal structure of R1Bm endonuclease domain | | 分子名称: | ACETIC ACID, Non-LTR retrotransposon R1Bmks ORF2 protein | | 著者 | Maita, N, Aoyagi, H, Osanai, M, Shirakawa, M, Fujiwara, H. | | 登録日 | 2007-03-12 | | 公開日 | 2007-07-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterization of the sequence specificity of the R1Bm endonuclease domain by structural and biochemical studies.
Nucleic Acids Res., 35, 2007
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3WO3
 | | Crystal structure of IL-18 in complex with IL-18 receptor alpha | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | | 登録日 | 2013-12-19 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
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3W6H
 | | Crystal structure of 19F probe-labeled hCAI in complex with acetazolamide | | 分子名称: | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 1, ... | | 著者 | Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I. | | 登録日 | 2013-02-14 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.964 Å) | | 主引用文献 | Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR
To be published
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