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5FUA
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BU of 5fua by Molmil
Cryo-EM of BK polyomavirus
分子名称: MAJOR CAPSID PROTEIN VP1
著者Hurdiss, D.L, Morgan, E.L, Thompson, R.F, Prescott, E.L, Panou, M.M, Macdonald, A, Ranson, N.A.
登録日2016-01-22
公開日2016-04-20
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献New Structural Insights Into the Genome and Minor Capsid Proteins of Bk Polyomavirus Using Cryo-Electron Microscopy.
Structure, 24, 2016
1JPS
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BU of 1jps by Molmil
Crystal structure of tissue factor in complex with humanized Fab D3h44
分子名称: immunoglobulin Fab D3H44, heavy chain, light chain, ...
著者Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
登録日2001-08-03
公開日2002-02-03
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
5FP6
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BU of 5fp6 by Molmil
Structure of cyclin-dependent kinase 2 with small-molecule ligand 3-(4,7-dichloro-1H-indol-3-yl)prop-2-yn-1-ol (AT17833) in an alternate binding site.
分子名称: 3-(4,7-dichloro-1H-indol-3-yl)prop-2-yn-1-ol, CYCLIN-DEPENDENT KINASE 2
著者Jhoti, H, Ludlow, R.F, O'Reilly, M, Saini, H.K, Tickle, I.J, Verdonk, M.
登録日2015-11-27
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Detection of Secondary Binding Sites in Proteins Using Fragment Screening.
Proc.Natl.Acad.Sci.USA, 112, 2015
1JPT
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BU of 1jpt by Molmil
Crystal Structure of Fab D3H44
分子名称: immunoglobulin Fab D3H44, heavy chain, immunoglobulin Fab D3h44, ...
著者Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
登録日2001-08-03
公開日2002-02-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
5FPT
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BU of 5fpt by Molmil
Structure of hepatitis C virus (HCV) full-length NS3 complex with small-molecule ligand 2-(1-methyl-1H-indol-3-yl)acetic acid (AT3437) in an alternate binding site.
分子名称: (1-methyl-1H-indol-3-yl)acetic acid, HEPATITIS C VIRUS FULL-LENGTH NS3 COMPLEX
著者Jhoti, H, Ludlow, R.F, Saini, H.K, Tickle, I.J, Verdonk, M, Pathuri, P, Williams, P.A.
登録日2015-12-02
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Detection of Secondary Binding Sites in Proteins Using Fragment Screening.
Proc.Natl.Acad.Sci.USA, 112, 2015
4DC8
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BU of 4dc8 by Molmil
Crystal Structure of Myoglobin Unexposed to Excessive SONICC Imaging Laser Dose.
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Becker, M, Mulichak, A.M, Kissick, D.J, Fischetti, R.F, Keefe, L.J, Simpson, D.J.
登録日2012-01-17
公開日2013-01-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Towards protein-crystal centering using second-harmonic generation (SHG) microscopy.
Acta Crystallogr.,Sect.D, 69, 2013
2H1J
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BU of 2h1j by Molmil
3.1 A X-ray structure of putative Oligoendopeptidase F: Crystals grown by microfluidic seeding
分子名称: Oligoendopeptidase F, ZINC ION
著者Gerdts, C.J, Tereshko, V, Dementieva, I, Collart, F, Joachimiak, A, Kossiakoff, A, Ismagilov, R.F, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D)
登録日2006-05-16
公開日2006-06-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization.
Angew.Chem.Int.Ed.Engl., 45, 2006
2H1N
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BU of 2h1n by Molmil
3.0 A X-ray structure of putative oligoendopeptidase F: crystals grown by vapor diffusion technique
分子名称: Oligoendopeptidase F, UNKNOWN LIGAND, ZINC ION
著者Gerdts, C.J, Tereshko, V, Dementieva, I, Collart, F, Joachimiak, A, Kossiakoff, A, Ismagilov, R.F, Midwest Center for Structural Genomics (MCSG)
登録日2006-05-16
公開日2006-06-13
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Time-Controlled Microfluidic Seeding in nL-Volume Droplets To Separate Nucleation and Growth Stages of Protein Crystallization.
Angew.Chem.Int.Ed.Engl., 45, 2006
2H43
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Crystal Structure of Human Fragment D Complexed with Ala-His-Arg-Pro-amide
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Doolittle, R.F, Pandi, L.
登録日2006-05-23
公開日2006-12-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Differences in Binding Specificity for the Homologous gamma- and beta-Chain "Holes" on Fibrinogen: Exclusive Binding of Ala-His-Arg-Pro-amide by the beta-Chain Hole.
Biochemistry, 45, 2006
1K6Q
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BU of 1k6q by Molmil
Crystal structure of antibody Fab fragment D3
分子名称: immunoglobulin Fab D3, heavy chain, light chain
著者Faelber, K, Kelley, R.F, Kirchhofer, D, Muller, Y.A.
登録日2001-10-17
公開日2002-04-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of murine Fab D3 at 2.4 A resolution in comparison with the humanised Fab D3h44 (1.85A) provides structural insight into the humanisation process of the D3 anti-tissue factor antibody
To be Published
2I5N
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BU of 2i5n by Molmil
1.96 A X-ray structure of photosynthetic reaction center from Rhodopseudomonas viridis:Crystals grown by microfluidic technique
分子名称: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
著者Li, L, Mustafi, D, Fu, Q, Tereshko, V, Chen, D.L, Tice, J.D, Ismagilov, R.F.
登録日2006-08-25
公開日2006-09-19
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2R4S
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BU of 2r4s by Molmil
Crystal structure of the human beta2 adrenoceptor
分子名称: Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ...
著者Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K.
登録日2007-08-31
公開日2007-11-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Nature, 450, 2007
2P8O
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BU of 2p8o by Molmil
Crystal Structure of a Benzohydroxamic Acid/Vanadate complex bound to chymotrypsin A
分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ...
著者Moulin, A, Bell, J.H, Pratt, R.F, Ringe, D.
登録日2007-03-22
公開日2007-05-08
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic Acid: structure of the inert complex and its mechanistic interpretation.
Biochemistry, 46, 2007
4R3S
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BU of 4r3s by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23
分子名称: FV FRAGMENT(MAB6D8) HEAVY CHAIN, FV FRAGMENT(MAB6D8) LIGHT CHAIN, Merozoite surface protein
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-08-18
公開日2015-06-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate
Sci Rep, 5, 2015
2P9V
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BU of 2p9v by Molmil
Structure of AmpC beta-lactamase with cross-linked active site after exposure to small molecule inhibitor
分子名称: Beta-lactamase, PHOSPHATE ION
著者Babaoglu, K, Wyrembak, P.N, Pelto, R.B, Shoichet, B.K, Pratt, R.F.
登録日2007-03-26
公開日2007-08-14
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献O-Aryloxycarbonyl Hydroxamates: New beta-Lactamase Inhibitors That Cross-Link the Active Site.
J.Am.Chem.Soc., 129, 2007
8RAT
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BU of 8rat by Molmil
EFFECTS OF TEMPERATURE ON PROTEIN STRUCTURE AND DYNAMICS: X-RAY CRYSTALLOGRAPHIC STUDIES OF THE PROTEIN RIBONUCLEASE-A AT NINE DIFFERENT TEMPERATURES FROM 98 TO 320 K
分子名称: RIBONUCLEASE A
著者Tiltonjunior, R.F, Dewan, J.C, Petsko, G.A.
登録日1991-08-13
公開日1993-07-15
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Effects of temperature on protein structure and dynamics: X-ray crystallographic studies of the protein ribonuclease-A at nine different temperatures from 98 to 320 K.
Biochemistry, 31, 1992
2Q9I
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BU of 2q9i by Molmil
Crystal Structure of D-Dimer from Human Fibrin Complexed with Met-His-Arg-Pro-Tyr-amide.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrin B Knob (GHRPam), ...
著者Doolittle, R.F, Pandi, L.
登録日2007-06-12
公開日2007-12-11
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Probing the beta-chain hole of fibrinogen with synthetic peptides that differ at their amino termini
Biochemistry, 46, 2007
4QY8
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BU of 4qy8 by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30
分子名称: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-07-24
公開日2015-06-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.353 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
2QK8
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Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase
分子名称: Dihydrofolate reductase, METHOTREXATE
著者Bennett, B.C, Xu, H, Simmerman, R.F, Lee, R.E, Dealwis, C.G.
登録日2007-07-10
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase.
J.Med.Chem., 50, 2007
4QYO
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BU of 4qyo by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22
分子名称: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-07-24
公開日2015-06-03
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.208 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
2R4R
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BU of 2r4r by Molmil
Crystal structure of the human beta2 adrenoceptor
分子名称: Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ...
著者Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K.
登録日2007-08-31
公開日2007-11-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Nature, 450, 2007
4QXT
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BU of 4qxt by Molmil
Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with FC27-MSP2 14-30
分子名称: Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2
著者Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S.
登録日2014-07-22
公開日2015-06-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.
Sci Rep, 5, 2015
2Q8A
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BU of 2q8a by Molmil
Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody
分子名称: 1F9 heavy chain, 1F9 light chain, Apical membrane antigen 1
著者Gupta, A, Murphy, V.J, Anders, R.F, Batchelor, A.H.
登録日2007-06-10
公開日2007-10-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody.
PLoS Pathog., 3, 2007
2Q8B
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Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody
分子名称: 1F9 heavy chain, 1F9 light chain, Apical membrane antigen 1
著者Gupta, A, Murphy, V.J, Anders, R.F, Batchelor, A.H.
登録日2007-06-10
公開日2007-10-09
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody
Plos Pathog., 3, 2007
5C52
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Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
分子名称: DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ...
著者Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W.
登録日2015-06-19
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.637 Å)
主引用文献Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015

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