2QK8
Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase
Summary for 2QK8
| Entry DOI | 10.2210/pdb2qk8/pdb |
| Descriptor | Dihydrofolate reductase, METHOTREXATE (3 entities in total) |
| Functional Keywords | oxidoreductase, methotrexate, pteridine binding, nucleotide phosphate binding, pseudo-rossman fold |
| Biological source | Bacillus anthracis str. |
| Total number of polymer chains | 1 |
| Total formula weight | 19603.29 |
| Authors | Bennett, B.C.,Xu, H.,Simmerman, R.F.,Lee, R.E.,Dealwis, C.G. (deposition date: 2007-07-10, release date: 2007-08-28, Last modification date: 2023-08-30) |
| Primary citation | Bennett, B.C.,Xu, H.,Simmerman, R.F.,Lee, R.E.,Dealwis, C.G. Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase. J.Med.Chem., 50:4374-4381, 2007 Cited by PubMed: 17696333DOI: 10.1021/jm070319v PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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