7D10
 
 | | Human NKCC1 | | 分子名称: | PALMITIC ACID, Solute carrier family 12 member 2 | | 著者 | Zhang, S, Yang, M. | | 登録日 | 2020-09-12 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | The structural basis of function and regulation of neuronal cotransporters NKCC1 and KCC2.
Commun Biol, 4, 2021
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7FB8
 | | De Novo-Designed and Disulfide-Bridged Peptide Heterodimer - hd1 | | 分子名称: | ASP-ASP-LYS-ASP-CYS-ASP-GLU-TYR-CYS-LYS-LYS-THR-LYS-GLU-NH2, GLU-LE1-THR-GLY-HIS-ILE-GLU-GLY-PRO-THR-LE1-THR-LE1-HIS-CYS-LYS-NH2 | | 著者 | Yao, H, Yao, S, Zheng, Y, Moyer, A, Baker, D, Wu, C. | | 登録日 | 2021-07-08 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | De novo design and directed folding of disulfide-bridged peptide heterodimers.
Nat Commun, 13, 2022
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7FBA
 | | De Novo-Designed and Disulfide-Bridged Peptide Heterodimer - hd2 | | 分子名称: | ALA-LE1-CYS-GLU-CYS-GLY-PRO-THR-ARG-GLU-CYS-LYS-NH2, GLU-CYS-ARG-GLU-TYR-GLY-PRO-LE1-LYS-LE1-LE1-ALA-NH2 | | 著者 | Yao, H, Yao, S, Moyer, A, Zheng, Y, Baker, D, Wu, C. | | 登録日 | 2021-07-08 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | De novo design and directed folding of disulfide-bridged peptide heterodimers.
Nat Commun, 13, 2022
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8WPU
 | | Human calcium-sensing receptor(CaSR) bound to cinacalcet in complex with Gq protein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Ling, S.L, Meng, X.Y, Tian, C.L. | | 登録日 | 2023-10-10 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insights into asymmetric activation of the calcium-sensing receptor-G q complex.
Cell Res., 34, 2024
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8WPG
 | | Human calcium-sensing receptor bound with cinacalcet in detergent | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Ling, S.L, Meng, X.Y, Tian, C.L. | | 登録日 | 2023-10-10 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural insights into asymmetric activation of the calcium-sensing receptor-G q complex.
Cell Res., 34, 2024
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7XAT
 | | Structure of somatostatin receptor 2 bound with SST14. | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | | 登録日 | 2022-03-19 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues.
Cell Discov, 8, 2022
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7XAU
 | | Structure of somatostatin receptor 2 bound with octreotide. | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | | 登録日 | 2022-03-19 | | 公開日 | 2022-08-31 | | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | | 主引用文献 | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues.
Cell Discov, 8, 2022
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7X1T
 | | Structure of Thyrotropin-Releasing Hormone Receptor bound with Taltirelin. | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ScFv16, ... | | 著者 | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | | 登録日 | 2022-02-24 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue.
Cell Res., 32, 2022
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7X1U
 | | Structure of Thyrotropin-Releasing Hormone Receptor bound with an Endogenous Peptide Agonist TRH. | | 分子名称: | Endogenous Peptide Agonist TRH, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Yang, F, Zhang, H.H, Meng, X.Y, Li, Y.G, Zhou, Y.X, Ling, S.L, Liu, L, Shi, P, Tian, C.L. | | 登録日 | 2022-02-24 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Structural insights into thyrotropin-releasing hormone receptor activation by an endogenous peptide agonist or its orally administered analogue.
Cell Res., 32, 2022
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7XAV
 | | Structure of somatostatin receptor 2 bound with lanreotide. | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Bo, Q, Yang, F, Li, Y.G, Meng, X.Y, Zhang, H.H, Zhou, Y.X, Ling, S.L, Sun, D.M, Lv, P, Liu, L, Shi, P, Tian, C.L. | | 登録日 | 2022-03-19 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Structural insights into the activation of somatostatin receptor 2 by cyclic SST analogues.
Cell Discov, 8, 2022
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7XHO
 | | Structure of human inner kinetochore CCAN complex | | 分子名称: | CENP-W, Centromere protein C, Centromere protein H, ... | | 著者 | Tian, T, Wang, C.L, Yang, Z.S, Sun, L.F, Zang, J.Y. | | 登録日 | 2022-04-09 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Structural insights into human CCAN complex assembled onto DNA.
Cell Discov, 8, 2022
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7XHN
 | | Structure of human inner kinetochore CCAN-DNA complex | | 分子名称: | CENP-W, Centromere protein C, Centromere protein H, ... | | 著者 | Sun, L.F, Tian, T, Wang, C.L, Yang, Z.S, Zang, J.Y. | | 登録日 | 2022-04-09 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Structural insights into human CCAN complex assembled onto DNA.
Cell Discov, 8, 2022
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7VRD
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7V67
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8Z5J
 | | Beta-catenin Crystal Structure | | 分子名称: | Catenin beta-1 | | 著者 | Tim, F. | | 登録日 | 2024-04-18 | | 公開日 | 2024-05-22 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells.
J.Med.Chem., 67, 2024
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7Y5N
 | | Structure of 1:1 PAPP-A.ProMBP complex(half map) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone marrow proteoglycan, ... | | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | | 登録日 | 2022-06-17 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
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7Y5Q
 | | Structure of 1:1 PAPP-A.STC2 complex(half map) | | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION | | 著者 | Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J. | | 登録日 | 2022-06-17 | | 公開日 | 2023-01-11 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
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8Z61
 | | Human beta-catenin crystal structure | | 分子名称: | Catenin beta-1 | | 著者 | Tim, F. | | 登録日 | 2024-04-18 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting beta-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells.
J.Med.Chem., 67, 2024
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7VV8
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7W8O
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7W8K
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7W8R
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7W96
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7WE3
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7WEI
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