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8GTM
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BU of 8gtm by Molmil
Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL
分子名称: 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1
著者Cho, H.S, Kim, H.
登録日2022-09-08
公開日2023-09-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
8GTG
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BU of 8gtg by Molmil
Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-I-152 by XFEL
分子名称: 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N},~{N}-bis(2-methoxyethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1
著者Cho, H.S, Kim, H.
登録日2022-09-08
公開日2023-09-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser.
Exp.Mol.Med., 55, 2023
5D50
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BU of 5d50 by Molmil
Crystal structure of Rep-Ant complex from Salmonella-temperate phage
分子名称: Anti-repressor protein, Repressor
著者Son, S.H, Yoon, H.J, Ryu, S, Lee, H.H.
登録日2015-08-10
公開日2016-04-27
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Noncanonical DNA-binding mode of repressor and its disassembly by antirepressor
Proc.Natl.Acad.Sci.USA, 113, 2016
4W79
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BU of 4w79 by Molmil
Crystal Structure of Human Protein N-terminal Glutamine Amidohydrolase
分子名称: 1,2-ETHANEDIOL, CARBONATE ION, Protein N-terminal glutamine amidohydrolase, ...
著者Bitto, E, Bingman, C.A, McCoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG)
登録日2014-08-21
公開日2014-09-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway.
Plos One, 9, 2014
3NIQ
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BU of 3niq by Molmil
Crystal structure of Pseudomonas aeruginosa guanidinopropionase
分子名称: 3-guanidinopropionase, GLYCEROL, MANGANESE (II) ION
著者Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Jang, J.Y, Im, H, An, D, Suh, S.W.
登録日2010-06-16
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Crystal structures of Pseudomonas aeruginosa guanidinobutyrase and guanidinopropionase, members of the ureohydrolase superfamily
J.Struct.Biol., 175, 2011
3NIO
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BU of 3nio by Molmil
Crystal structure of Pseudomonas aeruginosa guanidinobutyrase
分子名称: Guanidinobutyrase, MANGANESE (II) ION
著者Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Jang, J.Y, Im, H, An, D, Suh, S.W.
登録日2010-06-16
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of Pseudomonas aeruginosa guanidinobutyrase and guanidinopropionase, members of the ureohydrolase superfamily
J.Struct.Biol., 175, 2011
3NIP
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BU of 3nip by Molmil
Crystal structure of Pseudomonas aeruginosa guanidinopropionase complexed with 1,6-diaminohexane
分子名称: 3-guanidinopropionase, HEXANE-1,6-DIAMINE
著者Lee, S.J, Kim, H.S, Kim, D.J, Yoon, H.J, Kim, K.H, Yoon, J.Y, Jang, J.Y, Im, H, An, D, Suh, S.W.
登録日2010-06-16
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of Pseudomonas aeruginosa guanidinobutyrase and guanidinopropionase, members of the ureohydrolase superfamily
J.Struct.Biol., 175, 2011
6EBO
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BU of 6ebo by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Unactivated Form
分子名称: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ...
著者Palowitch, G.M, Alapati, R.B, Boal, A.K.
登録日2018-08-06
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EBQ
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BU of 6ebq by Molmil
Crystal Structure of the Flavoprotein NrdI from Aerococcus urinae in Oxidized Form
分子名称: FLAVIN MONONUCLEOTIDE, Protein NrdI
著者Palowitch, G.M, Alapati, R.B, Boal, A.K.
登録日2018-08-06
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EBZ
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BU of 6ebz by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form with Thiocyanate Bound
分子名称: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ...
著者Palowitch, G.M, Boal, A.K.
登録日2018-08-07
公開日2018-09-19
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6EBP
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BU of 6ebp by Molmil
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form
分子名称: CALCIUM ION, GLYCEROL, Ribonucleoside-diphosphate reductase, ...
著者Palowitch, G.M, Boal, A.K.
登録日2018-08-06
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3F3M
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BU of 3f3m by Molmil
Six Crystal Structures of Two Phosphopantetheine Adenylyltransferases Reveal an Alternative Ligand Binding Mode and an Associated Structural Change
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, Phosphopantetheine adenylyltransferase
著者Lee, H.H, Yoon, H.J, Suh, S.W.
登録日2008-10-31
公開日2009-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3'-phosphoadenosine 5'-phosphosulfate reveals a new ligand-binding mode
Acta Crystallogr.,Sect.F, 65, 2009
6XI8
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BU of 6xi8 by Molmil
Yeast TFIIK (Kin28/Ccl1/Tfb3) Complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Cyclin CCL1, ...
著者van Eeuwen, T, Murakami, K, Li, T, Tsai, K.L.
登録日2020-06-19
公開日2021-04-28
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structure of TFIIK for phosphorylation of CTD of RNA polymerase II.
Sci Adv, 7, 2021
6MIH
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BU of 6mih by Molmil
Crystal structure of host-guest complex with PC hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*(1WA)P*CP*(DB)P*T)-3'), DNA (5'-D(P*AP*(DS)P*GP*(1W5)P*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIG
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BU of 6mig by Molmil
Crystal structure of host-guest complex with PB hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), Gag-Pol polyprotein
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6MIK
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BU of 6mik by Molmil
Crystal structure of host-guest complex with PP hachimoji DNA
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(DS))-3'), DNA (5'-D(P*(DB)P*(1W5)P*(1W5)P*AP*TP*AP*AP*G)-3'), N-terminal fragment of MMLV reverse transcriptase
著者Georgiadis, M.M.
登録日2018-09-19
公開日2019-02-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Hachimoji DNA and RNA: A genetic system with eight building blocks.
Science, 363, 2019
6B1Q
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BU of 6b1q by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(CJ1)P*(CJ1)P*(CJ1))-3'), DNA (5'-D(P*(1AP)P*(1AP)P*(1AP)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
6B1S
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BU of 6b1s by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*AP*(CGY)P*(CGY)P*TP*TP*TP*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
5CSS
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BU of 5css by Molmil
Crystal structure of triosephosphate isomerase from Thermoplasma acidophilum with glycerol 3-phosphate
分子名称: CHLORIDE ION, SN-GLYCEROL-3-PHOSPHATE, Triosephosphate isomerase
著者Park, S.H, Kim, H.S, Song, M.K, Kim, K.R, Park, J.S, Han, B.W.
登録日2015-07-23
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure and Stability of the Dimeric Triosephosphate Isomerase from the Thermophilic Archaeon Thermoplasma acidophilum.
Plos One, 10, 2015
6B1R
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BU of 6b1r by Molmil
Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
分子名称: DNA (5'-D(*CP*TP*TP*AP*TP*(1WA)P*(1WA)P*(1WA))-3'), DNA (5'-D(P*(IGU)P*(IGU)P*(IGU)P*AP*TP*AP*AP*G)-3'), Reverse transcriptase
著者Singh, I, Georgiadis, M.M.
登録日2017-09-18
公開日2018-09-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献"Skinny" and "Fat" DNA: Two New Double Helices.
J. Am. Chem. Soc., 140, 2018
5WQ0
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BU of 5wq0 by Molmil
Receiver domain of Spo0A from Paenisporosarcina sp. TG-14
分子名称: MAGNESIUM ION, Stage 0 sporulation protein
著者Lee, J.H, Lee, C.W.
登録日2016-11-22
公開日2017-03-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Crystal structure of the inactive state of the receiver domain of Spo0A from Paenisporosarcina sp. TG-14, a psychrophilic bacterium isolated from an Antarctic glacier
J. Microbiol., 55, 2017
5C7U
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BU of 5c7u by Molmil
5'-monophosphate wt Guanine Riboswitch bound to hypoxanthine.
分子名称: 5'-monophosphate wt guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE
著者Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A.
登録日2015-06-24
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
5CSR
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BU of 5csr by Molmil
Crystal structure of triosephosphate isomerase from Thermoplasma acidophilium
分子名称: CHLORIDE ION, GLYCEROL, Triosephosphate isomerase
著者Park, S.H, Kim, H.S, Song, M.K, Park, H.S, Han, B.W.
登録日2015-07-23
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure and Stability of the Dimeric Triosephosphate Isomerase from the Thermophilic Archaeon Thermoplasma acidophilum.
Plos One, 10, 2015
5C7W
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BU of 5c7w by Molmil
5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine.
分子名称: 5'-monophosphate Z:P guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE
著者Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A.
登録日2015-06-25
公開日2015-08-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair.
Angew.Chem.Int.Ed.Engl., 54, 2015
7YC5
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BU of 7yc5 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with K202.B bispecific antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from K202.B, bispecific antibody, ...
著者Yoo, Y, Cho, H.S.
登録日2022-06-30
公開日2023-07-05
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants.
Antiviral Res., 212, 2023

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