6EBO

Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Unactivated Form

Summary for 6EBO

• Entry DOI: 10.2210/pdb6ebo/pdb
• Descriptor: Ribonucleoside-diphosphate reductase, beta subunit, CALCIUM ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: ribonucleotide reductase, beta subunit, rnr, r2, class ie, metal-free, oxidoreductase
• Biological source: Aerococcus urinae (strain ACS-120-V-Col10a)
• Total number of polymer chains: 4
• Total formula weight: 163274.39

Authors

Palowitch, G.M.,Alapati, R.B.,Boal, A.K. (deposition date: 2018-08-06, release date: 2018-09-19, Last modification date: 2023-10-11)

• Primary citation: Blaesi, E.J.,Palowitch, G.M.,Hu, K.,Kim, A.J.,Rose, H.R.,Alapati, R.,Lougee, M.G.,Kim, H.J.,Taguchi, A.T.,Tan, K.O.,Laremore, T.N.,Griffin, R.G.,Krebs, C.,Matthews, M.L.,Silakov, A.,Bollinger Jr., J.M.,Allen, B.D.,Boal, A.K.; Metal-free class Ie ribonucleotide reductase from pathogens initiates catalysis with a tyrosine-derived dihydroxyphenylalanine radical.; Proc. Natl. Acad. Sci. U.S.A., 115:10022-10027, 2018; PubMed: 30224458; DOI: 10.1073/pnas.1811993115

Experimental method

X-RAY DIFFRACTION (1.58 Å)