1GXP
 
 | | PhoB effector domain in complex with pho box DNA. | | 分子名称: | 5'-D(*CP*CP*CP*GP*TP*GP*AP*CP*AP*AP* CP*TP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*T)-3', 5'-D(*GP*AP*GP*CP*TP*GP*TP*CP*AP*TP* AP*AP*AP*GP*TP*TP*GP*TP*CP*AP*CP*GP*G)-3', PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN | | 著者 | Blanco, A.G, Sola, M, Gomis-Ruth, F.X, Coll, M. | | 登録日 | 2002-04-08 | | 公開日 | 2002-04-29 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Tandem DNA Recognition by Two-Component Signal Transduction Transcriptional Activator Phob
Structure, 10, 2002
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2IYN
 | | The co-factor-induced pre-active conformation in PhoB | | 分子名称: | MAGNESIUM ION, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB | | 著者 | Sola, M, Drew, D.L, Blanco, A.G, Gomis-Ruth, F.X, Coll, M. | | 登録日 | 2006-07-19 | | 公開日 | 2006-08-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | The Cofactor-Induced Pre-Active Conformation in Phob.
Acta Crystallogr.,Sect.D, 62, 2006
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2IWB
 | | MecR1 unbound extracellular antibiotic-sensor domain. | | 分子名称: | GLYCEROL, METHICILLIN RESISTANCE MECR1 PROTEIN, NICKEL (II) ION, ... | | 著者 | Marrero, A, Mallorqui-Fernandez, G, Guevara, T, Garcia-Castellanos, R, Gomis-Ruth, F.X. | | 登録日 | 2006-06-27 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance.
J.Mol.Biol., 361, 2006
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2IWC
 | | Benzylpenicilloyl-acylated MecR1 extracellular antibiotic-sensor domain. | | 分子名称: | METHICILLIN RESISTANCE MECR1 PROTEIN, OPEN FORM - PENICILLIN G | | 著者 | Marrero, A, Mallorqui-Fernandez, G, Guevara, T, Garcia-Castellanos, R, Gomis-Ruth, F.X. | | 登録日 | 2006-06-27 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance.
J.Mol.Biol., 361, 2006
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2IWA
 | | Unbound glutaminyl cyclotransferase from Carica papaya. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLUTAMINE CYCLOTRANSFERASE, ... | | 著者 | Guevara, T, Mallorqui-Fernandez, N, Garcia-Castellanos, R, Petersen, G.E, Lauritzen, C, Pedersen, J, Arnau, J, Gomis-Ruth, F.X, Sola, M. | | 登録日 | 2006-06-27 | | 公開日 | 2006-07-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Papaya Glutamine Cyclotransferase Shows a Singular Five-Fold Beta-Propeller Architecture that Suggests a Novel Reaction Mechanism.
Biol.Chem., 387, 2006
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2IWD
 | | Oxacilloyl-acylated MecR1 extracellular antibiotic-sensor domain. | | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Methicillin resistance mecR1 protein | | 著者 | Marrero, A, Mallorqui-Fernandez, G, Guevara, T, Garcia-Castellanos, R, Gomis-Ruth, F.X. | | 登録日 | 2006-06-27 | | 公開日 | 2006-07-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Unbound and Acylated Structures of the Mecr1 Extracellular Antibiotic-Sensor Domain Provide Insights Into the Signal-Transduction System that Triggers Methicillin Resistance.
J.Mol.Biol., 361, 2006
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4YTB
 | | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) in complex with dipeptide Asp-Gln. | | 分子名称: | ASPARTIC ACID, AZIDE ION, CHLORIDE ION, ... | | 著者 | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | | 登録日 | 2015-03-17 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
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4YU5
 | | Crystal structure of selenomethionine variant of Bacillus anthracis immune inhibitor A2 peptidase zymogen | | 分子名称: | 3-(1-methylpiperidinium-1-yl)propane-1-sulfonate, CALCIUM ION, GLYCEROL, ... | | 著者 | Arolas, J.L, Goulas, T, Gomis-Ruth, F.X. | | 登録日 | 2015-03-18 | | 公開日 | 2015-10-28 | | 最終更新日 | 2016-01-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome.
Structure, 24, 2016
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4YTG
 | | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) mutant C351A in complex with dipeptide Met-Arg. | | 分子名称: | ARGININE, AZIDE ION, CHLORIDE ION, ... | | 著者 | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | | 登録日 | 2015-03-17 | | 公開日 | 2015-07-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
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4YT9
 | | Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase (PPAD) substrate-unbound. | | 分子名称: | GLYCEROL, Peptidylarginine deiminase, SODIUM ION | | 著者 | Goulas, T, Mizgalska, D, Garcia-Ferrer, I, Kantyka, T, Guevara, T, Szmigielski, B, Sroka, A, Millan, C, Uson, I, Veillard, F, Potempa, B, Mydel, P, Sola, M, Potempa, J, Gomis-Ruth, F.X. | | 登録日 | 2015-03-17 | | 公開日 | 2015-07-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase.
Sci Rep, 5, 2015
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4YU6
 | | Crystal structure of Bacillus anthracis immune inhibitor A2 peptidase zymogen | | 分子名称: | ACETONITRILE, CALCIUM ION, Immune inhibitor A, ... | | 著者 | Arolas, J.L, Goulas, T, Gomis-Ruth, F.X. | | 登録日 | 2015-03-18 | | 公開日 | 2015-10-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural Basis for Latency and Function of Immune Inhibitor A Metallopeptidase, a Modulator of the Bacillus anthracis Secretome.
Structure, 24, 2016
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4HX3
 | | Crystal structure of Streptomyces caespitosus sermetstatin in complex with S. caespitosus snapalysin | | 分子名称: | Extracellular small neutral protease, GLYCEROL, Neutral proteinase inhibitor ScNPI, ... | | 著者 | Trillo-Muyo, S, Martinez-Rodriguez, S, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2012-11-09 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
CHEM SCI, 4, 2013
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4IJA
 | | Structure of S. aureus methicillin resistance factor MecR2 | | 分子名称: | GLYCEROL, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Arede, P, Botelho, T, Guevara, T, Uson, I, Oliveira, D.C, Gomis-Ruth, F.X. | | 登録日 | 2012-12-21 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Function Studies of the Staphylococcal Methicillin Resistance Antirepressor MecR2.
J.Biol.Chem., 288, 2013
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4JIX
 | | Crystal structure of the metallopeptidase zymogen of Methanocaldococcus jannaschii jannalysin | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Lopez-Pelegrin, M, Cerda-Costa, N, Martinez-Jimenez, F, Cintas-Pedrola, A, Canals, A, Peinado, J.R, Marti-Renom, M.A, Lopez-Otin, C, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2013-03-07 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases
J.Biol.Chem., 288, 2013
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4JIU
 | | Crystal structure of the metallopeptidase zymogen of Pyrococcus abyssi abylysin | | 分子名称: | GLYCEROL, Proabylysin, ZINC ION | | 著者 | Lopez-Pelegrin, M, Cerda-Costa, N, Martinez-Jimenez, F, Cintas-Pedrola, A, Canals, A, Peinado, J.R, Marti-Renom, M.A, Lopez-Otin, C, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2013-03-07 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | A novel family of soluble minimal scaffolds provides structural insight into the catalytic domains of integral membrane metallopeptidases
J.Biol.Chem., 288, 2013
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4HE5
 | | Crystal structure of the selenomethionine variant of the C-terminal domain of Geobacillus thermoleovorans putative U32 peptidase | | 分子名称: | Peptidase family U32, SULFATE ION | | 著者 | Trillo-Muyo, S, Jasilionis, A, Domagalski, M.J, Chruszcz, M, Minor, W, Kuisiene, N, Arolas, J.L, Sola, M, Gomis-Ruth, F.X. | | 登録日 | 2012-10-03 | | 公開日 | 2012-11-14 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Ultratight crystal packing of a 10 kDa protein.
Acta Crystallogr.,Sect.D, 69, 2013
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4GWM
 | | Crystal structure of human promeprin beta | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. | | 登録日 | 2012-09-03 | | 公開日 | 2012-09-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane
Proc.Natl.Acad.Sci.USA, 109, 2012
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4HX2
 | | Crystal structure of Streptomyces caespitosus sermetstatin in complex with Bacillus licheniformis subtilisin | | 分子名称: | (2R,2'R)-3,3'-oxydipropane-1,2-diol, ACETATE ION, CACODYLATE ION, ... | | 著者 | Trillo-Muyo, S, Martinez-Rodriguez, S, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2012-11-09 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
CHEM SCI, 4, 2013
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4HWX
 | | Crystal structure of Streptomyces caespitosus sermetstatin | | 分子名称: | ACETATE ION, GLYCEROL, Neutral proteinase inhibitor ScNPI | | 著者 | Trillo-Muyo, S, Martinez-Rodriguez, S, Arolas, J.L, Gomis-Ruth, F.X. | | 登録日 | 2012-11-09 | | 公開日 | 2012-12-05 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes
CHEM SCI, 4, 2013
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4GWN
 | | Crystal structure of human mature meprin beta | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Arolas, J.L, Broder, C, Jefferson, T, Guevara, T, Sterchi, E.E, Bode, W, Stocker, W, Becker-Pauly, C, Gomis-Ruth, F.X. | | 登録日 | 2012-09-03 | | 公開日 | 2012-09-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for the sheddase function of human meprin beta metalloproteinase at the plasma membrane
Proc.Natl.Acad.Sci.USA, 109, 2012
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4IEF
 | | Complex of Porphyromonas gingivalis RgpB pro- and mature domains | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BARIUM ION, CALCIUM ION, ... | | 著者 | de Diego, I, Veillard, F.T, Guevara, T, Potempa, B, Sztukowska, M, Potempa, J, Gomis-Ruth, F.X. | | 登録日 | 2012-12-13 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases.
J.Biol.Chem., 288, 2013
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4HE6
 | | Crystal structure of the C-terminal domain of Geobacillus thermoleovorans putative U32 peptidase | | 分子名称: | ACETATE ION, Peptidase family U32, UNKNOWN ATOM OR ION | | 著者 | Trillo-Muyo, S, Jasilionis, A, Domagalski, M.J, Chruszcz, M, Minor, W, Kuisiene, N, Arolas, J.L, Sola, M, Gomis-Ruth, F.X. | | 登録日 | 2012-10-03 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Ultratight crystal packing of a 10 kDa protein.
Acta Crystallogr.,Sect.D, 69, 2013
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3AIG
 | | ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL656 | | 分子名称: | (3R)-2-[N-(furan-2-ylcarbonyl)-L-leucyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid, ADAMALYSIN II, CALCIUM ION, ... | | 著者 | Gomis-Rueth, F.X, Meyer, E.F, Kress, L.F, Politi, V. | | 登録日 | 1997-10-12 | | 公開日 | 1998-04-15 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor alpha convertase inhibitors.
Protein Sci., 7, 1998
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2AIG
 | | ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL647 | | 分子名称: | ADAMALYSIN II, CALCIUM ION, N-(furan-2-ylcarbonyl)-L-leucyl-L-tryptophan, ... | | 著者 | Gomis-Rueth, F.X, Meyer, E.F, Kress, L.F, Politi, V. | | 登録日 | 1997-10-12 | | 公開日 | 1998-04-15 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor alpha convertase inhibitors.
Protein Sci., 7, 1998
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2CPG
 | | TRANSCRIPTIONAL REPRESSOR COPG | | 分子名称: | CHLORIDE ION, TRANSCRIPTIONAL REPRESSOR COPG | | 著者 | Gomis-Rueth, F.X, Sola, M, Acebo, P, Parraga, A, Guasch, A, Eritja, R, Gonzalez, A, Espinosa, M, del Solar, G, Coll, M. | | 登録日 | 1999-11-15 | | 公開日 | 1999-11-19 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator.
EMBO J., 17, 1998
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