2CM6
| crystal structure of the C2B domain of rabphilin3A | 分子名称: | CALCIUM ION, PHOSPHATE ION, RABPHILIN-3A | 著者 | Schlicker, C, Montaville, P, Sheldrick, G.M, Becker, S. | 登録日 | 2006-05-04 | 公開日 | 2006-12-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The C2A-C2B Linker Defines the High Affinity Ca2+ Binding Mode of Rabphilin-3A. J.Biol.Chem., 282, 2007
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2CA7
| Conkunitzin-S1 Is The First Member Of A New Kunitz-Type Neurotoxin Family- Structural and Functional Characterization | 分子名称: | CONKUNITZIN-S1 | 著者 | Bayrhuber, M, Vijayan, V, Ferber, M, Graf, R, Korukottu, J, Imperial, J, Garrett, J.E, Olivera, B.M, Terlau, H, Zweckstetter, M, Becker, S. | 登録日 | 2005-12-19 | 公開日 | 2006-01-05 | 最終更新日 | 2020-01-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization. J. Biol. Chem., 280, 2005
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2CM5
| crystal structure of the C2B domain of rabphilin | 分子名称: | CALCIUM ION, RABPHILIN-3A | 著者 | Schlicker, C, Montaville, P, Sheldrick, G.M, Becker, S. | 登録日 | 2006-05-04 | 公開日 | 2006-12-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | The C2A-C2B Linker Defines the High Affinity Ca2+ Binding Mode of Rabphilin-3A. J.Biol.Chem., 282, 2007
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6R99
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6V5D
| EROS3 RDC and NOE Derived Ubiquitin Ensemble | 分子名称: | Ubiquitin | 著者 | Lange, O.F, Lakomek, N.A, Smith, C.A, Griesinger, C, de Groot, B.L. | 登録日 | 2019-12-04 | 公開日 | 2020-01-01 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Enhancing NMR derived ensembles with kinetics on multiple timescales. J.Biomol.Nmr, 74, 2020
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6QD8
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6QCU
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4YXS
| CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITH PKI-5-24 | 分子名称: | N-BENZYL-9H-PURIN-6-AMINE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | 著者 | Schiffer, A, Wendt, K.U. | 登録日 | 2015-03-23 | 公開日 | 2015-05-20 | 最終更新日 | 2015-06-03 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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4YXR
| CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH inhibitor. | 分子名称: | 3-methyl-2H-indazole, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | 著者 | Schiffer, A, Wendt, K.U. | 登録日 | 2015-03-23 | 公開日 | 2015-05-27 | 最終更新日 | 2015-06-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
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6QD7
| EM structure of a EBOV-GP bound to 3T0331 neutralizing antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, Envelope glycoprotein,Virion spike glycoprotein,EBOV-GP1, ... | 著者 | Diskin, R, Cohen-Dvashi, H. | 登録日 | 2019-01-01 | 公開日 | 2019-10-02 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV. Nat. Med., 25, 2019
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1H2C
| Ebola virus matrix protein VP40 N-terminal domain in complex with RNA (High-resolution VP40[55-194] variant). | 分子名称: | 5'-R(*UP*GP*AP)-3', MATRIX PROTEIN VP40 | 著者 | Gomis-Ruth, F.X, Dessen, A, Bracher, A, Klenk, H.D, Weissenhorn, W. | 登録日 | 2002-08-05 | 公開日 | 2003-04-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Matrix Protein Vp40 from Ebola Virus Octamerizes Into Pore-Like Structures with Specific RNA Binding Properties Structure, 11, 2003
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1H2D
| Ebola virus matrix protein VP40 N-terminal domain in complex with RNA (Low-resolution VP40[31-212] variant). | 分子名称: | 5'-R(*UP*GP*AP)-3', CHLORIDE ION, MATRIX PROTEIN VP40 | 著者 | Gomis-Ruth, F.X, Dessen, A, Bracher, A, Klenk, H.D, Weissenhorn, W. | 登録日 | 2002-08-06 | 公開日 | 2003-04-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Matrix Protein Vp40 from Ebola Virus Octamerizes Into Pore-Like Structures with Specific RNA Binding Properties Structure, 11, 2003
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7NXZ
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6Y2G
| Crystal structure (orthorhombic form) of the complex resulting from the reaction between SARS-CoV-2 (2019-nCoV) main protease and tert-butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate (alpha-ketoamide 13b) | 分子名称: | 3C-like proteinase nsp5, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | 著者 | Zhang, L, Lin, D, Sun, X, Hilgenfeld, R. | 登録日 | 2020-02-15 | 公開日 | 2020-03-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved alpha-ketoamide inhibitors. Science, 368, 2020
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6Y2F
| Crystal structure (monoclinic form) of the complex resulting from the reaction between SARS-CoV-2 (2019-nCoV) main protease and tert-butyl (1-((S)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate (alpha-ketoamide 13b) | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | 著者 | Zhang, L, Lin, D, Sun, X, Hilgenfeld, R. | 登録日 | 2020-02-15 | 公開日 | 2020-03-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved alpha-ketoamide inhibitors. Science, 368, 2020
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6Y7M
| Crystal structure of the complex resulting from the reaction between the SARS-CoV main protease and tert-butyl (1-((S)-3-cyclohexyl-1-(((S)-4-(cyclopropylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclohexyl-1-[[(2~{S},3~{R})-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | 著者 | Zhang, L, Lin, D, Hilgenfeld, R. | 登録日 | 2020-03-01 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved alpha-ketoamide inhibitors. Science, 368, 2020
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6Y2E
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4ZG4
| Myosin Vc Pre-powerstroke | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ropars, V, Pylypenko, O, Sweeney, L, Houdusse, A. | 登録日 | 2015-04-22 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Force-producing ADP state of myosin bound to actin. Proc.Natl.Acad.Sci.USA, 113, 2016
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7QI2
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6HYI
| Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.4 A resolution in complex with inosine | 分子名称: | INOSINE, Protein kinase A regulatory subunit | 著者 | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | 登録日 | 2018-10-22 | 公開日 | 2019-11-13 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.39944851 Å) | 主引用文献 | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12, 2024
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6H4G
| Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant bound to cAMP in the A site | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, INOSINE, Protein kinase A regulatory subunit | 著者 | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | 登録日 | 2018-07-21 | 公開日 | 2019-08-14 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.143517 Å) | 主引用文献 | Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens. Elife, 12, 2024
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7JZJ
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7JZT
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1GIB
| MU-CONOTOXIN GIIIB, NMR | 分子名称: | MU-CONOTOXIN GIIIB | 著者 | Hill, J.M, Alewood, P.F, Craik, D.J. | 登録日 | 1996-04-17 | 公開日 | 1996-11-08 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of mu-conotoxin GIIIB, a specific blocker of skeletal muscle sodium channels. Biochemistry, 35, 1996
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2LGC
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