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6VU8
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BU of 6vu8 by Molmil
Structure of G-alpha-i bound to its chaperone Ric-8A
分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans)
著者Seven, A.B, Hilger, D.
登録日2020-02-14
公開日2020-03-18
最終更新日2020-03-25
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structures of G alpha Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.
Cell Rep, 30, 2020
7MTQ
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BU of 7mtq by Molmil
CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495
分子名称: 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2
著者Seven, A.B, Barros-Alvarez, X, Skiniotis, G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献G-protein activation by a metabotropic glutamate receptor.
Nature, 595, 2021
7MTR
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BU of 7mtr by Molmil
CryoEM Structure of Full-Length mGlu2 Bound to Ago-PAM ADX55164 and Glutamate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine, GLUTAMIC ACID, ...
著者Seven, A.B, Barros-Alvarez, X, Skiniotis, G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-09-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献G-protein activation by a metabotropic glutamate receptor.
Nature, 595, 2021
7MTS
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BU of 7mts by Molmil
CryoEM Structure of mGlu2 - Gi Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-methoxy-6-propyl-N-(2-{4-[(1H-tetrazol-5-yl)methoxy]phenyl}ethyl)thieno[2,3-d]pyrimidin-4-amine, GLUTAMIC ACID, ...
著者Seven, A.B, Barros-Alvarez, X, Skiniotis, G.
登録日2021-05-13
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献G-protein activation by a metabotropic glutamate receptor.
Nature, 595, 2021
8E0G
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BU of 8e0g by Molmil
Re-refined model of active mu-opioid receptor (PDB 5c1m) as an adduct with BU72
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3S,3aR,5aR,6R,11bR,11cS)-3a-methoxy-3,14-dimethyl-2-phenyl-2,3,3a,6,7,11c-hexahydro-1H-6,11b-(epiminoethano)-3,5a-methanonaphtho[2,1-g]indol-10-ol, CHOLESTEROL, ...
著者Munro, T.A.
登録日2022-08-09
公開日2023-10-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Reanalysis of a mu opioid receptor crystal structure reveals a covalent adduct with BU72.
Bmc Biol., 21, 2023
4PNJ
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BU of 4pnj by Molmil
Recombinant Sperm Whale P6 Myoglobin Solved with Single Pulse Free Electron Laser Data
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Cohen, A, Gonzalez, A, Lam, W, Lyubimov, A, Sauter, N, Tsai, Y, Uervirojnangkoorn, M, Brunger, A, Soltis, M.
登録日2014-05-23
公開日2014-11-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 111, 2014
7RKY
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BU of 7rky by Molmil
Binding mode of US27-Gi-scFv16 in OCL-state
分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, GUANOSINE-5'-DIPHOSPHATE, ...
著者Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKN
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BU of 7rkn by Molmil
Structure of CX3CL1-US28-Gi-scFv16 in OC-state
分子名称: Antibody fragment scFv16, Fractalkine, G-protein coupled receptor homolog US28, ...
著者Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKX
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BU of 7rkx by Molmil
Structure of US27-Gi-scFv16 in CL-state
分子名称: Antibody fragment scFv16, G-protein coupled receptor homolog US27, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Tsutsumi, N, Jude, K.M, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
7RKM
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BU of 7rkm by Molmil
Structure of CX3CL1-US28-Gi-scFv16 in C-state
分子名称: Antibody fragment scFv16, CHOLESTEROL, Fractalkine, ...
著者Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C.
登録日2021-07-22
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins
Sci Adv, 8, 2022
5D6K
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BU of 5d6k by Molmil
PepT - CIM
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Di-or tripeptide:H+ symporter, ...
著者Ma, P, Caffrey, M.
登録日2015-08-12
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The cubicon method for concentrating membrane proteins in the cubic mesophase.
Nat Protoc, 12, 2017
5D6L
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BU of 5d6l by Molmil
beta2AR-T4L - CIM
分子名称: (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, ACETAMIDE, ...
著者Ma, P, Caffrey, M.
登録日2015-08-12
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The cubicon method for concentrating membrane proteins in the cubic mesophase.
Nat Protoc, 12, 2017
5D6I
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BU of 5d6i by Molmil
DgkA - CIM
分子名称: Diacylglycerol kinase
著者Ma, P, Caffrey, M.
登録日2015-08-12
公開日2016-08-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.091 Å)
主引用文献The cubicon method for concentrating membrane proteins in the cubic mesophase.
Nat Protoc, 12, 2017
8GHV
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BU of 8ghv by Molmil
Cannabinoid Receptor 1-G Protein Complex
分子名称: (5Z,8Z,11Z,13S,14Z)-N-[(2R)-1-hydroxypropan-2-yl]-13-methylicosa-5,8,11,14-tetraenamide, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Krishna Kumar, K, Robertson, M.J, Skiniotis, G, Kobilka, B.K.
登録日2023-03-12
公開日2023-05-24
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for activation of CB1 by an endocannabinoid analog.
Nat Commun, 14, 2023
8UO3
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BU of 8uo3 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class S)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNM
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BU of 8unm by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class B)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNQ
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BU of 8unq by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class F)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNV
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BU of 8unv by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class K)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNZ
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BU of 8unz by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class O)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UO4
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BU of 8uo4 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class T)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNP
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BU of 8unp by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class E)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNU
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BU of 8unu by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class J)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UO0
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BU of 8uo0 by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class P)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNL
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BU of 8unl by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class A)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024
8UNR
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BU of 8unr by Molmil
CryoEM structure of beta-2-adrenergic receptor in complex with GTP-bound Gs heterotrimer (Class G)
分子名称: (5R,6R)-6-(methylamino)-5,6,7,8-tetrahydronaphthalene-1,2,5-triol, Beta-2 adrenergic receptor, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papasergi-Scott, M.M, Skiniotis, G.
登録日2023-10-19
公開日2024-03-06
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Time-resolved cryo-EM of G-protein activation by a GPCR.
Nature, 629, 2024

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