8GHV

Cannabinoid Receptor 1-G Protein Complex

Summary for 8GHV

• Entry DOI: 10.2210/pdb8ghv/pdb
• EMDB information: 40052 40057 40058
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• Functional Keywords: gpcr, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 5
• Total formula weight: 169786.29

Authors

Krishna Kumar, K.,Robertson, M.J.,Skiniotis, G.,Kobilka, B.K. (deposition date: 2023-03-12, release date: 2023-05-24)

• Primary citation: Krishna Kumar, K.,Robertson, M.J.,Thadhani, E.,Wang, H.,Suomivuori, C.M.,Powers, A.S.,Ji, L.,Nikas, S.P.,Dror, R.O.,Inoue, A.,Makriyannis, A.,Skiniotis, G.,Kobilka, B.; Structural basis for activation of CB1 by an endocannabinoid analog.; Nat Commun, 14:2672-2672, 2023; PubMed: 37160876; DOI: 10.1038/s41467-023-37864-4

Experimental method

ELECTRON MICROSCOPY (2.8 Å)