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2AIX
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BU of 2aix by Molmil
X-ray structure of the GLUR2 ligand-binding core (S1S2J) in complex with (s)-thio-atpa at 2.2 a resolution.
分子名称: (S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-YL) PROPRIONIC ACID, Glutamate receptor 2
著者Kastrup, J.S.
登録日2005-08-01
公開日2005-08-09
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Distinct kinetics of ionotropic glutamate receptor 2 splice variants characterized by fast agonist application and crystallization of a receptor-ligand complex.
To be Published
7U1Z
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BU of 7u1z by Molmil
Crystal structure of the DRBD and CROPs of TcdA
分子名称: SULFATE ION, Toxin A
著者Baohua, C, Peng, C, Kay, P, Rongsheng, J.
登録日2022-02-22
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Structure and conformational dynamics of Clostridioides difficile toxin A.
Life Sci Alliance, 5, 2022
7U2P
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BU of 7u2p by Molmil
Structure of TcdA GTD in complex with RhoA
分子名称: GUANOSINE-5'-DIPHOSPHATE, Glucosyltransferase TcdA, MAGNESIUM ION, ...
著者Baohua, C, Zheng, L, Kay, P, Rongsheng, J.
登録日2022-02-24
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition.
Sci Rep, 12, 2022
7UBX
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BU of 7ubx by Molmil
Structure of a pore forming fragment of Clostridium difficile toxin A in complex with VHH AA6
分子名称: Nanobody VHH AA6, Toxin A
著者Chen, B, Rongsheng, J, Kay, P.
登録日2022-03-15
公開日2022-11-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies.
Front Immunol, 13, 2022
1XHY
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BU of 1xhy by Molmil
X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution
分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor, SULFATE ION
著者Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S.
登録日2004-09-21
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.
Mol.Pharmacol., 67, 2005
7UBY
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BU of 7uby by Molmil
Structure of the GTD domain of Clostridium difficile toxin A in complex with VHH AH3
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Glucosyltransferase TcdA, ...
著者Chen, B, Rongsheng, J, Kay, P.
登録日2022-03-15
公開日2022-11-16
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies.
Front Immunol, 13, 2022
6O9U
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BU of 6o9u by Molmil
KirBac3.1 at a resolution of 2 Angstroms
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3,3',3''-phosphoryltripropanoic acid, BARIUM ION, ...
著者Gulbis, J.M, Clarke, O.B.
登録日2019-03-15
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun, 11, 2020
6O9T
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BU of 6o9t by Molmil
KirBac3.1 mutant at a resolution of 4.1 Angstroms
分子名称: 2,3,5,6-tetramethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, Inward rectifier potassium channel Kirbac3.1, POTASSIUM ION
著者Gulbis, J.M, Black, K.A, Miller, D.M.
登録日2019-03-15
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun, 11, 2020
6O9V
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BU of 6o9v by Molmil
KirBac3.1 mutant at a resolution of 3.1 Angstroms
分子名称: 1,1-Methanediyl Bismethanethiosulfonate, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Inward rectifier potassium channel Kirbac3.1, ...
著者Gulbis, J.M, Black, K.A, Miller, D.M.
登録日2019-03-15
公開日2020-05-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.094 Å)
主引用文献A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun, 11, 2020
7S0Z
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BU of 7s0z by Molmil
Structures of TcdB in complex with R-Ras
分子名称: 1,2-ETHANEDIOL, ACETATE ION, AMMONIUM ION, ...
著者Zheng, L, Rongsheng, J, Peng, C.
登録日2021-08-31
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Sci Adv, 7, 2021
7S0Y
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BU of 7s0y by Molmil
Structures of TcdB in complex with Cdc42
分子名称: Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Zheng, L, Rongsheng, J, Peng, C.
登録日2021-08-31
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural basis for selective modification of Rho and Ras GTPases by Clostridioides difficile toxin B.
Sci Adv, 7, 2021
3H6H
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BU of 3h6h by Molmil
Crystal structure of the GluR6 amino terminal domain dimer assembly MPD form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Glutamate receptor, ...
著者Kumar, J, Mayer, M.L.
登録日2009-04-23
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献The N-terminal domain of GluR6-subtype glutamate receptor ion channels.
Nat.Struct.Mol.Biol., 16, 2009
3H6G
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BU of 3h6g by Molmil
Crystal structure of the GluR6 amino terminal domain dimer assembly
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Glutamate receptor, ...
著者Kumar, J, Mayer, M.L.
登録日2009-04-23
公開日2009-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.697 Å)
主引用文献The N-terminal domain of GluR6-subtype glutamate receptor ion channels.
Nat.Struct.Mol.Biol., 16, 2009
8WRH
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BU of 8wrh by Molmil
SARS-CoV-2 XBB.1.5.70 in complex with ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S2'
著者Feng, L.L, Feng, L.L.
登録日2023-10-14
公開日2023-11-29
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.
Plos Pathog., 19, 2023
8WRL
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BU of 8wrl by Molmil
XBB.1.5 RBD in complex with ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1
著者Feng, L.L, Feng, L.L.
登録日2023-10-15
公開日2023-11-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.
Plos Pathog., 19, 2023
8WRO
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BU of 8wro by Molmil
XBB.1.5.10 spike protein in complex with ACE2
分子名称: Processed angiotensin-converting enzyme 2, Spike glycoprotein,Spike glycoprotein,Spike glycoprotein,Fusion protein
著者Feng, L.L, Feng, L.L.
登録日2023-10-15
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.
Plos Pathog., 19, 2023
8WRM
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BU of 8wrm by Molmil
XBB.1.5 spike protein in complex with ACE2
分子名称: Processed angiotensin-converting enzyme 2, Spike glycoprotein
著者Feng, L.L, Feng, L.L.
登録日2023-10-15
公開日2023-12-06
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.34 Å)
主引用文献Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.
Plos Pathog., 19, 2023
8WTJ
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BU of 8wtj by Molmil
XBB.1.5.70 spike protein in complex with ACE2
分子名称: Processed angiotensin-converting enzyme 2, Spike glycoprotein
著者Feng, L.L, Feng, L.L.
登録日2023-10-18
公開日2023-12-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.64 Å)
主引用文献Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.
Plos Pathog., 19, 2023
8WTD
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BU of 8wtd by Molmil
XBB.1.5.10 RBD in complex with ACE2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S2'
著者Feng, L.L, Feng, L.L.
登録日2023-10-18
公開日2023-12-13
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding.
Plos Pathog., 19, 2023
1FTJ
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BU of 1ftj by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH GLUTAMATE AT 1.9 RESOLUTION
分子名称: GLUTAMATE RECEPTOR SUBUNIT 2, GLUTAMIC ACID, ZINC ION
著者Armstrong, N, Gouaux, E.
登録日2000-09-12
公開日2000-11-01
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
8XRY
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BU of 8xry by Molmil
Cryo-EM structure of OSCA3.1-1.1ver(Y367N-G454S-Y458I)-open/open state
分子名称: CSC1-like protein ERD4
著者Zhang, Y, Han, Y.
登録日2024-01-08
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XNG
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BU of 8xng by Molmil
Cryo-EM structure of OSCA1.2-liposome-inside-out closed state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2023-12-29
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XW3
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BU of 8xw3 by Molmil
Cryo-EM structure of OSCA1.2-DOPC-1:50-expanded state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.63 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XS4
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BU of 8xs4 by Molmil
Cryo-EM structure of OSCA1.2-DOPC-1:20-contracted1 state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2024-01-08
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XW1
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Cryo-EM structure of OSCA1.2-V335W-DDM state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.49 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024

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