8XNG

Cryo-EM structure of OSCA1.2-liposome-inside-out closed state

Summary for 8XNG

Entry DOI	10.2210/pdb8xng/pdb
EMDB information	38503
Descriptor	Calcium permeable stress-gated cation channel 1 (1 entity in total)
Functional Keywords	osca/tmem63 channel, mechanosensitive channel, plant protein
Biological source	Arabidopsis thaliana (thale cress)
Total number of polymer chains	2
Total formula weight	178007.33
Authors	Zhang, Y.,Han, Y. (deposition date: 2023-12-29, release date: 2024-04-10, Last modification date: 2024-04-17)
Primary citation	Han, Y.,Zhou, Z.,Jin, R.,Dai, F.,Ge, Y.,Ju, X.,Ma, X.,He, S.,Yuan, L.,Wang, Y.,Yang, W.,Yue, X.,Chen, Z.,Sun, Y.,Corry, B.,Cox, C.D.,Zhang, Y. Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 2024 Cited by PubMed: 38570680 DOI: 10.1038/s41586-024-07256-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.56 Å)

Structure validation