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7VUE
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BU of 7vue by Molmil
Structural insight of the molecular mechanism of cilofexor bound to FXR
分子名称: 2-[3-[4-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-2-chloranyl-phenyl]-3-oxidanyl-azetidin-1-yl]pyridine-4-carboxylic acid, Bile acid receptor, Peptide from Nuclear receptor coactivator 2
著者Jiang, L, Chen, Y.C.
登録日2021-11-02
公開日2022-03-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Structural insight into the molecular mechanism of cilofexor binding to the farnesoid X receptor.
Biochem.Biophys.Res.Commun., 595, 2022
1DSW
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BU of 1dsw by Molmil
THE SOLUTION STRUCTURE OF A MONOMERIC, REDUCED FORM OF HUMAN COPPER, ZINC SUPEROXIDE DISMUTASE BEARING THE SAME CHARGE AS THE NATIVE PROTEIN
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE (CU-ZN), ZINC ION
著者Banci, L, Bertini, I, Del Conte, R, Fadin, R, Mangani, S, Viezzoli, M.S.
登録日2000-01-10
公開日2000-03-22
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献The solution structure of a monomeric, reduced form of human copper,zinc superoxide dismutase bearing the same charge as the native protein.
J.Biol.Inorg.Chem., 4, 1999
7VFB
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BU of 7vfb by Molmil
the complex of SARS-CoV2 3cl and NB2B4
分子名称: 3C-like proteinase, nb2b4
著者Geng, Y, Sun, Z.C, Wang, L.
登録日2021-09-11
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An extended conformation of SARS-CoV-2 main protease reveals allosteric targets.
Proc.Natl.Acad.Sci.USA, 119, 2022
1DXK
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BU of 1dxk by Molmil
Metallo-beta-lactamase from Bacillus cereus 569/H/9 C168S mutant
分子名称: BICARBONATE ION, CLASS B BETA-LACTAMASE, ZINC ION
著者Chantalat, L, Duee, E, Dideberg, O.
登録日2000-01-10
公開日2000-08-25
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase.
Protein Sci., 9, 2000
7V8G
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BU of 7v8g by Molmil
Crystal structure of HOIP RING1 domain bound to IpaH1.4 LRR domain
分子名称: E3 ubiquitin-protein ligase RNF31, RING-type E3 ubiquitin transferase, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-23
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8E
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BU of 7v8e by Molmil
Crystal structure of IpaH1.4 LRR domain bound to HOIL-1L UBL domain.
分子名称: RING-type E3 ubiquitin transferase, RanBP-type and C3HC4-type zinc finger-containing protein 1
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
7V8F
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BU of 7v8f by Molmil
Crystal structure of UBE2L3 bound to HOIP RING1 domain.
分子名称: E3 ubiquitin-protein ligase RNF31, Ubiquitin-conjugating enzyme E2 L3, ZINC ION
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-22
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
1E1G
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BU of 1e1g by Molmil
Human prion protein variant M166V
分子名称: PRION PROTEIN
著者Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K.
登録日2000-05-04
公開日2000-07-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR Structures of Three Single-Residue Variants of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
7VFA
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the complex of SARS-CoV2 3CL and NB1A2
分子名称: 3C-like proteinase, NB1A2, SULFATE ION
著者Sun, Z.C, Wang, L, Geng, Y.
登録日2021-09-11
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献An extended conformation of SARS-CoV-2 main protease reveals allosteric targets.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VPN
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BU of 7vpn by Molmil
Crystal Structure of the dioxygenase CcTet from Coprinopsis cinereain in complex with Mn(II) and N-Oxalylglycine
分子名称: CcTet molecule, MANGANESE (II) ION, N-OXALYLGLYCINE
著者Mu, Y.J, Zhang, L, Zhang, L.
登録日2021-10-17
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A fungal dioxygenase CcTet serves as a eukaryotic 6mA demethylase on duplex DNA.
Nat.Chem.Biol., 18, 2022
7V8H
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BU of 7v8h by Molmil
Crystal structure of LRR domain from Shigella flexneri IpaH1.4
分子名称: RING-type E3 ubiquitin transferase
著者Liu, J, Wang, Y, Pan, L.
登録日2021-08-23
公開日2022-03-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
Proc.Natl.Acad.Sci.USA, 119, 2022
1DOL
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BU of 1dol by Molmil
MONOCYTE CHEMOATTRACTANT PROTEIN 1, I-FORM
分子名称: MONOCYTE CHEMOATTRACTANT PROTEIN 1
著者Lubkowski, J, Bujacz, G, Boque, L, Wlodawer, A.
登録日1996-11-22
公開日1997-03-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions.
Nat.Struct.Biol., 4, 1997
1DQ1
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BU of 1dq1 by Molmil
Calcium;Calcium concanavalin A
分子名称: CALCIUM ION, Concanavalin-Br
著者Bouckaert, J, Dewallef, Y, Poortmans, F, Wyns, L, Loris, R.
登録日1999-12-29
公開日2000-01-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structural features of concanavalin A governing non-proline peptide isomerization
J.Biol.Chem., 275, 2000
1DZQ
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BU of 1dzq by Molmil
LECTIN UEA-II COMPLEXED WITH GALACTOSE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, LECTIN II, ...
著者Loris, R, De Greve, H, Dao-Thi, M.-H, Messens, J, Imberty, A, Wyns, L.
登録日2000-03-07
公開日2000-06-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Basis of Carbohydrate Recognition by Lectin II from Ulex Europaeus, a Protein with a Promiscuous Carbohydrate Binding Site
J.Mol.Biol., 301, 2000
1E1U
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BU of 1e1u by Molmil
Human prion protein variant R220K
分子名称: PRION PROTEIN
著者Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K.
登録日2000-05-11
公開日2000-07-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR Structures of Three Single-Residue Variants of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
1DYP
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BU of 1dyp by Molmil
1,3-ALPHA-1,4-BETA-D-GALACTOSE-4-SULFATE-3,6-ANHYDRO-D-GALACTOSE 4 GALACTOHYDROLASE
分子名称: CADMIUM ION, CHLORIDE ION, KAPPA-CARRAGEENASE
著者Michel, G, Chantalat, L, Dideberg, O.
登録日2000-02-04
公開日2001-01-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献The Kappa-Carrageenase of P. Carrageenovora Features a Tunnel-Shaped Active Site: A Novel Insight in the Evolution of Clan-B Glycoside Hydrolases
Structure, 9, 2001
1E1P
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Human prion protein variant S170N
分子名称: PRION PROTEIN
著者Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K.
登録日2000-05-09
公開日2000-07-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR Structures of Three Single-Residue Variants of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
1DTH
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BU of 1dth by Molmil
METALLOPROTEASE
分子名称: 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, ATROLYSIN C, CALCIUM ION, ...
著者Botos, I, Scapozza, L, Zhang, D, Liotta, L.A, Meyer, E.F.
登録日1996-02-12
公開日1997-02-12
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding.
Proc.Natl.Acad.Sci.USA, 93, 1996
7FFT
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BU of 7fft by Molmil
The crystal structure of a domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica
分子名称: Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Wang, L, Bu, T, Bai, X.
登録日2021-07-23
公開日2021-09-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica.
Acta Crystallogr D Struct Biol, 78, 2022
7FFW
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The crystal structure of a domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, METHOXYETHANE, ...
著者Wang, L, Bu, T, Bai, X.
登録日2021-07-23
公開日2021-09-15
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the domain-swapped dimeric maltodextrin-binding protein MalE from Salmonella enterica.
Acta Crystallogr D Struct Biol, 78, 2022
1DO9
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BU of 1do9 by Molmil
SOLUTION STRUCTURE OF OXIDIZED MICROSOMAL RABBIT CYTOCHROME B5. FACTORS DETERMINING THE HETEROGENEOUS BINDING OF THE HEME.
分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Banci, L, Bertini, I, Rosato, A, Scacchieri, S.
登録日1999-12-20
公開日2000-01-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of oxidized microsomal rabbit cytochrome b5. Factors determining the heterogeneous binding of the heme.
Eur.J.Biochem., 267, 2000
1DT1
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THERMUS THERMOPHILUS CYTOCHROME C552 SYNTHESIZED BY ESCHERICHIA COLI
分子名称: CYTOCHROME C552, HEME C
著者Fee, J.A, Chen, Y, Hill, M.J, Gomez-Moran, E, Loehr, T, Ai, J, Thony-Meyer, L, Williams, P.A, Stura, E, Sridhar, V, McRee, D.E.
登録日2000-01-10
公開日2000-02-18
最終更新日2021-03-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Integrity of thermus thermophilus cytochrome c552 synthesized by Escherichia coli cells expressing the host-specific cytochrome c maturation genes, ccmABCDEFGH: biochemical, spectral, and structural characterization of the recombinant protein.
Protein Sci., 9, 2000
1DZ5
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The NMR structure of the 38KDa U1A protein-PIE RNA complex reveals the basis of cooperativity in regulation of polyadenylation by human U1A protein
分子名称: PIE, RNA (5'-R(*GP*AP*GP*AP*CP*AP*UP*UP*GP*CP*AP*CP*CP* CP*GP*GP*AP*GP*UP*CP*UP*C)-3'), U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
著者Varani, L, Gunderson, S.I, Mattaj, I.W, Kay, L.E, Neuhaus, D, Varani, G.
登録日2000-02-16
公開日2000-03-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The NMR Structure of the 38kDa U1A Protein-Pie RNA Complex Reveals the Basis of Cooperativity in Regulation of Polyadenylation by Human U1A Protein
Nat.Struct.Biol., 7, 2000
1E1J
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Human prion protein variant M166V
分子名称: PRION PROTEIN
著者Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K.
登録日2000-05-09
公開日2000-07-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR Structures of Three Single-Residue Variants of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
1G37
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CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN COMPLEXED WITH BCH-10556 AND EXOSITE-DIRECTED PEPTIDE
分子名称: 3-(4-AMINO-CYCLOHEXYL)-2-HYDROXY-3-[(4-OXO-2-PHENYLMETHANESULFONYL-1,2,3,4-TETRAHYDRO-PYRROLO[1,2-A]PYRAZINE-6-CARBONYL)-AMINO]-PROPIONIC ACID BUTYL ESTER, ALPHA THROMBIN, THROMBIN NONAPEPTIDE INHIBITOR
著者Bachand, B, Tarazi, M, St-Denis, Y, Edmunds, J.J, Winocour, P.D, Leblond, L, Siddiqui, M.A.
登録日2000-10-23
公開日2001-04-21
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Potent and selective bicyclic lactam inhibitors of thrombin. Part 4: transition state inhibitors.
Bioorg.Med.Chem.Lett., 11, 2001

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