4N9X
| Crystal Structure of the OCTAPRENYL-METHYL-METHOXY-BENZQ MOLECULE from Erwina carotovora subsp. atroseptica strain SCRI 1043 / ATCC BAA-672, Northeast Structural Genomics Consortium (NESG) Target EwR161 | 分子名称: | Putative monooxygenase | 著者 | Kuzin, A, Chen, Y, Lew, S, Seetharaman, J, Mao, L, Xiao, R, Owens, L.A, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-10-21 | 公開日 | 2013-11-20 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Crystal Structure of the OCTAPRENYL-METHYL-METHOXY-BENZQ MOLECULE from Erwina carotovora subsp. atroseptica strain SCRI 1043 / ATCC BAA-672, Northeast Structural Genomics Consortium (NESG) Target EwR161 To be Published
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1M6X
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3GWB
| Crystal structure of peptidase M16 inactive domain from Pseudomonas fluorescens. Northeast Structural Genomics target PlR293L | 分子名称: | Peptidase M16 inactive domain family protein | 著者 | Seetharaman, J, Chen, Y, Fang, F, Xiao, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-03-31 | 公開日 | 2009-05-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of peptidase M16 inactive domain from Pseudomonas fluorescens. Northeast Structural Genomics target PlR293L To be Published
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4NT9
| Crystal structure of an L,D-carboxypeptidase DacB from Streptococcus pneumonia | 分子名称: | ACETATE ION, GLYCEROL, Putative uncharacterized protein, ... | 著者 | Yang, Y.H, Zhang, J, Jiang, Y.L, Zhou, C.Z, Chen, Y. | 登録日 | 2013-12-02 | 公開日 | 2014-11-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.705 Å) | 主引用文献 | Crystal structure of an L,D-carboxypeptidase DacB from Streptococcus pneumonia To be Published
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3EVI
| Crystal structure of the thioredoxin-fold domain of human phosducin-like protein 2 | 分子名称: | DI(HYDROXYETHYL)ETHER, Phosducin-like protein 2, SODIUM ION | 著者 | Lou, X, Bao, R, Zhou, C, Chen, Y. | 登録日 | 2008-10-13 | 公開日 | 2009-03-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the thioredoxin-fold domain of human phosducin-like protein 2 Acta Crystallogr.,Sect.F, 65, 2009
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3ESH
| Crystal structure of a probable metal-dependent hydrolase from Staphylococcus aureus. Northeast Structural Genomics target ZR314 | 分子名称: | Protein similar to metal-dependent hydrolase | 著者 | Seetharaman, J, Chen, Y, Wang, H, Janjua, H, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-10-06 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a probable metal-dependent hydrolase from
Staphylococcus aureus. Northeast Structural Genomics target ZR314 To be Published
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1MN9
| NDP kinase mutant (H122G) complex with RTP | 分子名称: | MAGNESIUM ION, NDP kinase, RIBAVIRIN TRIPHOSPHATE | 著者 | Gallois-montbrun, S, Chen, Y, Dutartre, H, Morera, S, Guerreiro, C, Mulard, L, Schneider, B, Janin, J, Canard, B, Veron, M, Deville-bonne, D. | 登録日 | 2002-09-05 | 公開日 | 2003-03-18 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets MOL.PHARMACOL., 63, 2003
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1MN7
| NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP | 分子名称: | 3'-AZIDO-3'-DEOXY-THYMIDINE-5'-ALPHA BORANO TRIPHOSPHATE, MAGNESIUM ION, NDP kinase | 著者 | gallois-montbrun, s, schneider, b, chen, y, giacomoni-fernandes, v, mulard, l, morera, s, janin, j, deville-bonne, d, veron, m. | 登録日 | 2002-09-05 | 公開日 | 2002-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation J.BIOL.CHEM., 277, 2002
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3GQQ
| Crystal structure of the human retinal protein 4 (unc-119 homolog A). Northeast Structural Genomics Consortium target HR3066a | 分子名称: | Protein unc-119 homolog A, UNKNOWN LIGAND | 著者 | Vorobiev, S.M, Chen, Y, Seetharaman, J, Shastry, R, Foote, E.L, Ciccosanti, C, Sahdev, S, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-03-24 | 公開日 | 2009-04-07 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | 主引用文献 | Crystal structure of the human retinal protein 4 (unc-119 homolog A). To be Published
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2QYK
| Crystal structure of PDE4A10 in complex with inhibitor NPV | 分子名称: | 4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid, Cyclic AMP-specific phosphodiesterase HSPDE4A10, MAGNESIUM ION, ... | 著者 | Wang, H, Peng, M, Chen, Y, Geng, J, Robinson, H, Houslay, M. | 登録日 | 2007-08-15 | 公開日 | 2008-04-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of the four subfamilies of phosphodiesterase-4 provide insight into the selectivity of their inhibitors. Biochem.J., 408, 2007
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7CH1
| The overall structure of SLC26A9 | 分子名称: | CHLORIDE ION, SODIUM ION, Solute carrier family 26 member 9 | 著者 | Chi, X.M, Chen, Y, Li, X.R, Zhang, Y.Y, Zhou, Q. | 登録日 | 2020-07-03 | 公開日 | 2020-08-26 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence. Cell Discov, 6, 2020
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4KWE
| GDP-bound, double-stranded, curved FtsZ protofilament structure | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE | 著者 | Li, Y, Hsin, J, Zhao, L, Cheng, Y, Shang, W, Huang, K.C, Wang, H.W, Ye, S. | 登録日 | 2013-05-23 | 公開日 | 2013-07-31 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | FtsZ protofilaments use a hinge-opening mechanism for constrictive force generation Science, 341, 2013
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4JZA
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7F4H
| Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein, Nb35 and scFv16 | 分子名称: | Afamelanotide, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | 登録日 | 2021-06-18 | 公開日 | 2021-09-08 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor. Cell Res., 31, 2021
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7F4D
| Cryo-EM structure of alpha-MSH-bound melanocortin-1 receptor in complex with Gs protein and Nb35 | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | 登録日 | 2021-06-18 | 公開日 | 2021-09-08 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor. Cell Res., 31, 2021
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7F4F
| Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein and scFv16 | 分子名称: | Afamelanotide, CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | 登録日 | 2021-06-18 | 公開日 | 2021-09-08 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor. Cell Res., 31, 2021
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7F4I
| Cryo-EM structure of SHU9119-bound melanocortin-1 receptor in complex with Gs protein and Nb35 | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Ma, S, Chen, Y, Dai, A, Yin, W, Guo, J, Yang, D, Zhou, F, Jiang, Y, Wang, M.-W, Xu, H.E. | 登録日 | 2021-06-18 | 公開日 | 2021-09-08 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor. Cell Res., 31, 2021
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7F3S
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7F4E
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7F5M
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7F51
| Crystal structure of Hst2 in complex with 2'-O-Benzoyl ADP Ribose | 分子名称: | NAD-dependent protein deacetylase HST2, ZINC ION, [(2R,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] benzoate | 著者 | Wang, D, Yan, F, Chen, Y. | 登録日 | 2021-06-21 | 公開日 | 2022-03-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Global profiling of regulatory elements in the histone benzoylation pathway. Nat Commun, 13, 2022
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7D6C
| Crystal structure of CcmM N-terminal domain in complex with CcmN | 分子名称: | Carbon dioxide concentrating mechanism protein CcmM, Carboxysome assembly protein CcmN | 著者 | Sun, H, Cui, N, Han, S.J, Chen, Z.P, Xia, L.Y, Chen, Y, Jiang, Y.L, Zhou, C.Z. | 登録日 | 2020-09-30 | 公開日 | 2021-08-04 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Complex structure reveals CcmM and CcmN form a heterotrimeric adaptor in beta-carboxysome. Protein Sci., 30, 2021
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7DTY
| Structural basis of ligand selectivity conferred by the human glucose-dependent insulinotropic polypeptide receptor | 分子名称: | CHOLESTEROL, Gastric inhibitory polypeptide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, F.H, Zhang, C, Zhou, Q.T, Hang, K.N, Zou, X.Y, Chen, Y, Wu, F, Rao, Q.D, Dai, A.T, Yin, W.C, Shen, D.D, Zhang, Y, Xia, T, Stevens, R.C, Xu, H.E, Yang, D.H, Zhao, L.H, Wang, M.W. | 登録日 | 2021-01-06 | 公開日 | 2021-08-04 | 最終更新日 | 2021-08-11 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor. Elife, 10, 2021
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7EBL
| Bacterial STING in complex with c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), STING | 著者 | Ko, T.-P, Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2021-03-10 | 公開日 | 2021-09-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Crystal structure and functional implication of bacterial STING. Nat Commun, 13, 2022
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7EBD
| Bacterial STING in complex with c-di-GMP | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, TIR-like domain-containing protein | 著者 | Ko, T.-P, Wang, Y.-C, Yang, C.-S, Hou, M.-H, Chen, Y. | 登録日 | 2021-03-09 | 公開日 | 2021-09-15 | 最終更新日 | 2022-01-19 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure and functional implication of bacterial STING. Nat Commun, 13, 2022
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