7EBL

Bacterial STING in complex with c-di-GMP

Summary for 7EBL

Entry DOI	10.2210/pdb7ebl/pdb
Descriptor	STING, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) (3 entities in total)
Functional Keywords	second messenger, complex, cyclic dinucleotide, antiviral pathway, signaling protein
Biological source	Myroides sp. ZB35
Total number of polymer chains	2
Total formula weight	39057.01
Authors	Ko, T.-P.,Wang, Y.-C.,Yang, C.-S.,Hou, M.-H.,Chen, Y. (deposition date: 2021-03-10, release date: 2021-09-15, Last modification date: 2023-11-29)
Primary citation	Ko, T.-P.,Wang, Y.-C.,Yang, C.-S.,Hou, M.-H.,Chen, C.-J.,Chiu, Y.-F.,Chen, Y. Crystal structure and functional implication of bacterial STING. Nat Commun, 13:26-26, 2022 Cited by PubMed: 35013136 DOI: 10.1038/s41467-021-26583-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.17 Å)

Structure validation