7XQ1
 
 | | Structure of hSLC19A1+2'3'-CDAS | | 分子名称: | (1~{R},3~{S},6~{R},8~{R},9~{R},10~{S},12~{S},15~{R},17~{R},18~{R})-8,17-bis(6-aminopurin-9-yl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13,16-hexaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.2.1.0^{6,10}]octadecane-9,18-diol, Reduced folate transporter | | 著者 | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | | 登録日 | 2022-05-06 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
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7XPZ
 | | Structure of Apo-hSLC19A1 | | 分子名称: | Reduced folate transporter | | 著者 | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | | 登録日 | 2022-05-06 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
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7XQ0
 | | Structure of hSLC19A1+3'3'-CDA | | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Reduced folate transporter | | 著者 | Zhang, Q.X, Zhang, X.Y, Zhu, Y.L, Sun, P.P, Gao, A, Zhang, L.G, Gao, P. | | 登録日 | 2022-05-06 | | 公開日 | 2022-10-05 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Recognition of cyclic dinucleotides and folates by human SLC19A1.
Nature, 612, 2022
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3PVR
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3PVY
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8JNQ
 | | Crystal structure of cytochrome P450 CftA from Streptomyces torulosus NRRL B-3889, in complex with a substrate compound c | | 分子名称: | (1Z,3E,5E,7S,8R,10S,11R,13R,15R,16E,18E,25S)-11-ethyl-2,7-dihydroxy-10-methyl-21,26-diazatetracyclo[23.2.1.09,13.08,15]octacosa-1(2),3,5,16,18-pentaene-20,27,28-trione, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Jiang, P, Zhang, L.P, Zhang, C.S. | | 登録日 | 2023-06-06 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
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8JNP
 | | Crystal structure of cytochrome P450 CftA from Streptomyces torulosus NRRL B-3889, in complex with the substrate ikarugamycin | | 分子名称: | (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione, Cytochrome P450 CftA, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Jiang, P, Zhang, L.P, Zhang, C.S. | | 登録日 | 2023-06-06 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates.
Angew.Chem.Int.Ed.Engl., 62, 2023
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6F5M
 | | Crystal structure of highly glycosylated human leukocyte elastase in complex with a thiazolidinedione inhibitor | | 分子名称: | 5-[[4-[[(2~{S})-4-methyl-1-oxidanylidene-1-[(2-propylphenyl)amino]pentan-2-yl]carbamoyl]phenyl]methyl]-2-oxidanylidene-1,3-thiazol-1-ium-4-olate, ACETATE ION, Neutrophil elastase, ... | | 著者 | Hochscherf, J, Pietsch, M, Tieu, W, Kuan, K, Hautmann, S, Abell, A, Guetschow, M, Niefind, K. | | 登録日 | 2017-12-01 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of highly glycosylated human leukocyte elastase in complex with an S2' site binding inhibitor.
Acta Crystallogr F Struct Biol Commun, 74, 2018
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7BET
 | | Structure of Ribonucleotide reductase R2 from Escherichia coli collected by femtosecond serial crystallography on a COC membrane | | 分子名称: | FE (III) ION, Ribonucleoside-diphosphate reductase 1 subunit beta | | 著者 | Aurelius, O, John, J, Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Hogbom, M, Wang, M, Pedrini, B. | | 登録日 | 2020-12-24 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published
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1ORD
 | | CRYSTALLOGRAPHIC STRUCTURE OF A PLP-DEPENDENT ORNITHINE DECARBOXYLASE FROM LACTOBACILLUS 30A TO 3.1 ANGSTROMS RESOLUTION | | 分子名称: | ORNITHINE DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Hackert, M.L, Momany, C, Ernst, S, Ghosh, R. | | 登録日 | 1995-02-08 | | 公開日 | 1995-09-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystallographic structure of a PLP-dependent ornithine decarboxylase from Lactobacillus 30a to 3.0 A resolution.
J.Mol.Biol., 252, 1995
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8H2T
 | | Cryo-EM structure of IadD/E dioxygenase bound with IAA | | 分子名称: | 1H-INDOL-3-YLACETIC ACID, Aromatic-ring-hydroxylating dioxygenase beta subunit, FE (III) ION, ... | | 著者 | Yu, G, Li, Z, Zhang, H. | | 登録日 | 2022-10-07 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-01-03 | | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | | 主引用文献 | Structural and biochemical characterization of the key components of an auxin degradation operon from the rhizosphere bacterium Variovorax.
Plos Biol., 21, 2023
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7AT6
 | | Structure of thaumatin collected by femtosecond serial crystallography on a COC membrane | | 分子名称: | L(+)-TARTARIC ACID, R-1,2-PROPANEDIOL, SODIUM ION, ... | | 著者 | Martiel, I, Marsh, M, Vera, L, Huang, C.Y, Olieric, V, Leonarski, P, Nass, K, Padeste, C, Karpik, A, Wang, M, Pedrini, B. | | 登録日 | 2020-10-29 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Commissioning results from the SwissMX instrument for fixed target macromolecular crystallography at SwissFEL
To Be Published
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2FIV
 | | Crystal structure of feline immunodeficiency virus protease complexed with a substrate | | 分子名称: | ACE-ALN-VAL-STA-GLU-ALN-NH2, FELINE IMMUNODEFICIENCY VIRUS PROTEASE, SULFATE ION | | 著者 | Schalk-Hihi, C, Lubkowski, J, Zdanov, A, Wlodawer, A, Gustchina, A. | | 登録日 | 1997-07-21 | | 公開日 | 1997-11-12 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor.
Biochemistry, 36, 1997
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6UMJ
 | | Crystal structure of erenumab Fab-c | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,3-BUTANEDIOL, erenumab Fab heavy chain, ... | | 著者 | Mohr, C. | | 登録日 | 2019-10-09 | | 公開日 | 2020-02-12 | | 最終更新日 | 2020-02-26 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab).
Cell Rep, 30, 2020
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6UMG
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3ROK
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4XXI
 | | Crystal structure of the Bilin-binding domain of phycobilisome core-membrane linker ApcE | | 分子名称: | PHYCOCYANOBILIN, Phycobiliprotein ApcE | | 著者 | Tang, K, Ding, W.-L, Hoppner, A, Gartner, W, Zhao, K.-H. | | 登録日 | 2015-01-30 | | 公開日 | 2015-12-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The terminal phycobilisome emitter, LCM: A light-harvesting pigment with a phytochrome chromophore
Proc.Natl.Acad.Sci.USA, 112, 2015
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7ECW
 | | The Csy-AcrIF14-dsDNA complex | | 分子名称: | 54-MER DNA, AcrIF14, CRISPR type I-F/YPEST-associated protein Csy2, ... | | 著者 | Zhang, L.X, Feng, Y. | | 登録日 | 2021-03-13 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Insights into the dual functions of AcrIF14 during the inhibition of type I-F CRISPR-Cas surveillance complex.
Nucleic Acids Res., 49, 2021
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7ECV
 | | The Csy-AcrIF14 complex | | 分子名称: | AcrIF14, CRISPR type I-F/YPEST-associated protein Csy2, CRISPR-associated protein Csy3, ... | | 著者 | Zhang, L.X, Feng, Y. | | 登録日 | 2021-03-13 | | 公開日 | 2021-11-17 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.43 Å) | | 主引用文献 | Insights into the dual functions of AcrIF14 during the inhibition of type I-F CRISPR-Cas surveillance complex.
Nucleic Acids Res., 49, 2021
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7DZ9
 | | MbnABC complex | | 分子名称: | FE (III) ION, MbnA, MbnB, ... | | 著者 | Chao, D, Dan, Z, Yijun, G, Wei, C. | | 登録日 | 2021-01-25 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis.
Cell Res., 32, 2022
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3ROQ
 | | Crystal structure of human CD38 in complex with compound CZ-46 | | 分子名称: | (2R,3R,4S,5S)-4-fluoro-3,5-dihydroxytetrahydrofuran-2-yl 2-phenylethyl hydrogen (S)-phosphate, ADP-ribosyl cyclase 1 | | 著者 | Zhang, H, Lee, H.C, Hao, Q. | | 登録日 | 2011-04-26 | | 公開日 | 2011-12-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Catalysis-based inhibitors of the calcium signaling function of CD38.
Biochemistry, 51, 2012
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4XXU
 | | ModA - chromate bound | | 分子名称: | Chromate, Molybdate-binding periplasmic protein | | 著者 | He, C, Karpus, J, Ajiboye, I. | | 登録日 | 2015-01-30 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structure of chromate bound ModA from E.coli at 1.43 Angstroms resolution.
To Be Published
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8DKG
 | | Structure of PYCR1 Thr171Met variant complexed with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Isoform 3 of Pyrroline-5-carboxylate reductase 1, mitochondrial, ... | | 著者 | Meeks, K.R, Tanner, J.J. | | 登録日 | 2022-07-05 | | 公開日 | 2023-02-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Functional Impact of a Cancer-Related Variant in Human Delta 1 -Pyrroline-5-Carboxylate Reductase 1.
Acs Omega, 8, 2023
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4XXK
 | | Crystal structure of the Semet-derivative of the Bilin-binding domain of phycobilisome core-membrane linker ApcE | | 分子名称: | PHYCOCYANOBILIN, Phycobiliprotein ApcE | | 著者 | Tang, K, Ding, W.-L, Hoppner, A, Gartner, W, Zhao, K.-H. | | 登録日 | 2015-01-30 | | 公開日 | 2015-12-16 | | 最終更新日 | 2016-01-13 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | The terminal phycobilisome emitter, LCM: A light-harvesting pigment with a phytochrome chromophore.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6N7P
 | | S. cerevisiae spliceosomal E complex (UBC4) | | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Nuclear cap-binding protein complex subunit 1, Nuclear cap-binding protein subunit 2, ... | | 著者 | Liu, S, Li, X, Zhou, Z.H, Zhao, R. | | 登録日 | 2018-11-27 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | A unified mechanism for intron and exon definition and back-splicing.
Nature, 573, 2019
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