7XQ0

Structure of hSLC19A1+3'3'-CDA

Summary for 7XQ0

• Entry DOI: 10.2210/pdb7xq0/pdb
• EMDB information: 33387
• Descriptor: Reduced folate transporter, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide (2 entities in total)
• Functional Keywords: hslc19a1+3'3'-cda complex, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 61872.91

Authors

Zhang, Q.X.,Zhang, X.Y.,Zhu, Y.L.,Sun, P.P.,Gao, A.,Zhang, L.G.,Gao, P. (deposition date: 2022-05-06, release date: 2022-10-05, Last modification date: 2022-12-14)

• Primary citation: Zhang, Q.,Zhang, X.,Zhu, Y.,Sun, P.,Zhang, L.,Ma, J.,Zhang, Y.,Zeng, L.,Nie, X.,Gao, Y.,Li, Z.,Liu, S.,Lou, J.,Gao, A.,Zhang, L.,Gao, P.; Recognition of cyclic dinucleotides and folates by human SLC19A1.; Nature, 612:170-176, 2022; PubMed: 36265513; DOI: 10.1038/s41586-022-05452-z

Experimental method

ELECTRON MICROSCOPY (3 Å)