7XQ0

Structure of hSLC19A1+3'3'-CDA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Reduced folate transporter	polymer	544	60556.1	1	UniProt (P41440) Pfam (PF01770)	Homo sapiens (human)	FOLT,Intestinal folate carrier 1,IFC-1,Placental folate transporter,Reduced folate carrier protein,RFC,hRFC,Reduced folate transporter 1,RFT-1,Solute carrier family 19 member 1,hSLC19A1
2	B, C (A)	(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide	non-polymer		658.4	2	Chemie (2BA)

Sequence modifications

A: 1 - 506 (UniProt: P41440)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag
Lys 507	-	expression tag
Leu 508	-	expression tag
Gly 509	-	expression tag
Ser 510	-	expression tag
Glu 511	-	expression tag
Asn 512	-	expression tag
Leu 513	-	expression tag
Tyr 514	-	expression tag
Leu 515	-	expression tag
Glu 516	-	expression tag
Val 517	-	expression tag
Leu 518	-	expression tag
Phe 519	-	expression tag
Gln 520	-	expression tag
Gly 521	-	expression tag
Pro 522	-	expression tag
Phe 523	-	expression tag
Gln 524	-	expression tag
Gly 525	-	expression tag
Gly 526	-	expression tag
Ser 527	-	expression tag
Gly 528	-	expression tag
Gly 529	-	expression tag
Ser 530	-	expression tag
Gly 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	60556.1
Non-Polymers*	Number of molecules	2
	Total formula weight	1316.8
All*	Total formula weight	61872.9

*Water molecules are not included.