8JNP
Crystal structure of cytochrome P450 CftA from Streptomyces torulosus NRRL B-3889, in complex with the substrate ikarugamycin
Summary for 8JNP
Entry DOI | 10.2210/pdb8jnp/pdb |
Descriptor | Cytochrome P450 CftA, (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total) |
Functional Keywords | actinomadura viridis, hydrolase, lobophorin, deglycosylation, oxidoreductase |
Biological source | Streptomyces torulosus |
Total number of polymer chains | 1 |
Total formula weight | 45183.75 |
Authors | Jiang, P.,Zhang, L.P.,Zhang, C.S. (deposition date: 2023-06-06, release date: 2023-11-15, Last modification date: 2023-12-20) |
Primary citation | Jiang, P.,Jin, H.,Zhang, G.,Zhang, W.,Liu, W.,Zhu, Y.,Zhang, C.,Zhang, L. A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62:e202310728-e202310728, 2023 Cited by PubMed: 37917570DOI: 10.1002/anie.202310728 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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