6R0G
| Getah virus macro domain in complex with ADPr, pose 2 | 分子名称: | ACETATE ION, ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural polyprotein | 著者 | Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B. | 登録日 | 2019-03-12 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0P
| Getah virus macro domain in complex with ADPr in double open conformation | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Non-structural polyprotein, ... | 著者 | Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B. | 登録日 | 2019-03-13 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0F
| Getah virus macro domain in complex with ADPr, pose 1 | 分子名称: | Non-structural polyprotein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | 著者 | Sulzenbacher, G, Ferreira Ramos, A.S, Coutard, B. | 登録日 | 2019-03-12 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0T
| Getah virus macro domain in complex with ADPr in open conformation | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Non-structural polyprotein, ... | 著者 | Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B. | 登録日 | 2019-03-13 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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6R0R
| Getah virus macro domain in complex with ADPr covalently bond to Cys34 | 分子名称: | 1,2-ETHANEDIOL, Non-structural polyprotein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-2,3,4,5-tetrakis(oxidanyl)pentyl] hydrogen phosphate | 著者 | Ferreira Ramos, A.S, Sulzenbacher, G, Coutard, B. | 登録日 | 2019-03-13 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Snapshots of ADP-ribose bound to Getah virus macro domain reveal an intriguing choreography. Sci Rep, 10, 2020
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2FAV
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6S3A
| Coxsackie B3 2C protein in complex with S-Fluoxetine | 分子名称: | (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 2C protein, CHLORIDE ION, ... | 著者 | El Kazzi, P, Papageorgiou, N, Ferron, F.P, Bauer, L, van Kuppeveld, F, Coutard, B. | 登録日 | 2019-06-24 | 公開日 | 2021-01-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex. Sci Adv, 8, 2022
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6T3W
| Coxsackie B3 2C protein in complex with S-Fluoxetine | 分子名称: | (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 2C protein, SODIUM ION, ... | 著者 | El Kazzi, P, Papageorgiou, N, Ferron, F.P, Bauer, L, van Kuppeveld, F, Coutard, B. | 登録日 | 2019-10-11 | 公開日 | 2020-11-18 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex. Sci Adv, 8, 2022
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5M5B
| Crystal structure of Zika virus NS5 methyltransferase | 分子名称: | CHLORIDE ION, GLYCEROL, NS5 methyltransferase, ... | 著者 | Barral, K, Ortiz Lombardia, M, Coutard, B, Decroly, E, Lichiere, J. | 登録日 | 2016-10-21 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives. J. Virol., 91, 2017
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3ELU
| Wesselsbron virus Methyltransferase in complex with AdoMet | 分子名称: | Methyltransferase, S-ADENOSYLMETHIONINE, SULFATE ION | 著者 | Bollati, M, Ricagno, S, Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2008-09-23 | 公開日 | 2008-11-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol., 385, 2009
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3EMD
| Wesselsbron virus Methyltransferase in complex with Sinefungin and 7MeGpppA | 分子名称: | P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, SINEFUNGIN, SULFATE ION, ... | 著者 | Bollati, M, Milani, M, Ricagno, S, Mastrangelo, E, Bolognesi, M. | 登録日 | 2008-09-24 | 公開日 | 2008-11-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol., 385, 2009
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3EMB
| Wesselsbron virus Methyltransferase in complex with AdoMet and 7MeGpppG | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Methyltransferase, S-ADENOSYLMETHIONINE, ... | 著者 | Bollati, M, Ricagno, S, Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2008-09-24 | 公開日 | 2008-11-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol., 385, 2009
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3ELY
| Wesselsbron virus Methyltransferase in complex with AdoHcy | 分子名称: | DI(HYDROXYETHYL)ETHER, Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Bollati, M, Milani, M, Ricagno, S, Mastrangelo, E, Bolognesi, M. | 登録日 | 2008-09-23 | 公開日 | 2008-11-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol., 385, 2009
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3ELW
| Wesselsbron virus Methyltransferase in complex with AdoMet and GpppG | 分子名称: | DIGUANOSINE-5'-TRIPHOSPHATE, Methyltransferase, S-ADENOSYLMETHIONINE, ... | 著者 | Bollati, M, Ricagno, S, Milani, M, Mastrangelo, E, Bolognesi, M. | 登録日 | 2008-09-23 | 公開日 | 2008-11-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol., 385, 2009
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6SX8
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6SY8
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6T2A
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6T6L
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3ELD
| Wesselsbron methyltransferase in complex with Sinefungin | 分子名称: | Methyltransferase, SINEFUNGIN, SULFATE ION | 著者 | Bollati, M, Milani, M, Mastrangelo, E, Ricagno, S, Bolognesi, M. | 登録日 | 2008-09-22 | 公開日 | 2008-11-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Recognition of RNA Cap in the Wesselsbron Virus NS5 Methyltransferase Domain: Implications for RNA-Capping Mechanisms in Flavivirus J.Mol.Biol., 385, 2009
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7P27
| NMR solution structure of Chikungunya virus macro domain | 分子名称: | Polyprotein P1234 | 著者 | Lykouras, M.V, Tsika, A.C, Papageorgiou, N, Canard, B, Coutard, B, Bentrop, D, Spyroulias, G.A. | 登録日 | 2021-07-04 | 公開日 | 2022-07-13 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Binding Adaptation of GS-441524 Diversifies Macro Domains and Downregulates SARS-CoV-2 de-MARylation Capacity. J.Mol.Biol., 434, 2022
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5MQX
| NMR solution structure of macro domain from Venezuelan equine encephalitis virus(VEEV) in complex with ADP-ribose | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein3 | 著者 | Makrynitsa, G.I, Ntonti, D, Marousis, K.D, Matsoukas, M.T, Papageorgiou, N, Coutard, B, Bentrop, D, Spyroulias, G.A. | 登録日 | 2016-12-21 | 公開日 | 2018-07-04 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformational plasticity of the VEEV macro domain is important for binding of ADP-ribose. J.Struct.Biol., 206, 2019
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2HFZ
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2HCS
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2HCN
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2P3L
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