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Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 20 mM Na+ and zero Ca2+
分子名称:	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, CALCIUM ION, ...
著者	Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D.
登録日	2016-01-30
公開日	2016-05-11
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.101 Å)
主引用文献	Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016

5HXE

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 100 mM Na+ and zero Ca2+
分子名称:	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, PENTADECANE, ...
著者	Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D.
登録日	2016-01-30
公開日	2016-05-11
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.288 Å)
主引用文献	Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016

5HXS

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 10mM Sr2+
分子名称:	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, PENTADECANE, ...
著者	Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D.
登録日	2016-01-31
公開日	2016-05-11
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.789 Å)
主引用文献	Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016

5HXR

Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 10mM Ca2+
分子名称:	(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, PENTADECANE, ...
著者	Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D.
登録日	2016-01-31
公開日	2016-05-11
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.463 Å)
主引用文献	Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23, 2016

8JZS

Outward-facing SLC15A4 dimer
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, lysosomal transporter
著者	Zhang, S.S, Chen, X.D, Xie, M.
登録日	2023-07-06
公開日	2023-09-27
最終更新日	2023-12-13
実験手法	ELECTRON MICROSCOPY (2.95 Å)
主引用文献	Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023

8JZU

SLC15A4_TASL complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, TLR adapter,Green fluorescent protein, TSLAA-EGPF tag fusion protein
著者	Zhang, S.S, Chen, X.D, Xie, M.
登録日	2023-07-06
公開日	2023-09-27
最終更新日	2024-06-05
実験手法	ELECTRON MICROSCOPY (3.05 Å)
主引用文献	Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023

8JZR

Outward_facing SLC15A4 monomer
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, lysosomal transporter,ALFA tag
著者	Zhang, S.S, Chen, X.D, Xie, M.
登録日	2023-07-06
公開日	2023-09-27
最終更新日	2023-12-13
実験手法	ELECTRON MICROSCOPY (3.25 Å)
主引用文献	Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023

5KGO

Structure of K. pneumonia MrkH-c-di-GMP complex
分子名称:	9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Flagellar brake protein YcgR
著者	Schumacher, M.
登録日	2016-06-13
公開日	2016-08-17
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	To be published: Structures of K. pneumonia MrkH: dual utilization of the PilZ fold for c-di-GMP and DNA binding by a novel activator of biofilm genes To Be Published

5K58

Structure of the K. pneumonia SlmA-DNA complex bound to the C-terminal of the cell division protein FtsZ
分子名称:	DNA (5'-D(GPTPGPAPGPTPAPCPTPCPAPC)-3'), Nucleoid occlusion factor SlmA, Octapeptide
著者	Schumacher, M.
登録日	2016-05-23
公開日	2016-06-22
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (2.772 Å)
主引用文献	Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ. Proc. Natl. Acad. Sci. U.S.A., 113, 2016

5GP1

Crystal structure of ZIKV NS5 Methyltransferase in complex with GTP and SAH
分子名称:	NICKEL (II) ION, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, RNA-directed RNA polymerase NS5, ...
著者	Zhang, C, Jin, T.
登録日	2016-07-30
公開日	2016-12-07
最終更新日	2017-10-18
実験手法	X-RAY DIFFRACTION (2.444 Å)
主引用文献	Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design Biochem. Biophys. Res. Commun., 492, 2017

5GOZ

Crystal structure of ZIKV NS5 Methyltransferase in complex with GTP and SAH
分子名称:	GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, PYROPHOSPHATE 2-, ...
著者	Zhang, C, Jin, T.
登録日	2016-07-30
公開日	2016-12-07
最終更新日	2017-10-18
実験手法	X-RAY DIFFRACTION (2.049 Å)
主引用文献	Structure of the NS5 methyltransferase from Zika virus and implications in inhibitor design Biochem. Biophys. Res. Commun., 492, 2017

7LFY

Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+
分子名称:	CYCLIC GUANOSINE MONOPHOSPHATE, SODIUM ION, cGMP-gated cation channel alpha-1
著者	Xue, J, Han, Y, Jiang, Y.
登録日	2021-01-19
公開日	2021-03-10
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (3.6 Å)
主引用文献	Structural mechanisms of gating and selectivity of human rod CNGA1 channel. Neuron, 109, 2021

7LFT

Cryo-EM structure of human Apo CNGA1 channel in K+/Ca2+
分子名称:	1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CHOLESTEROL, POTASSIUM ION, ...
著者	Xue, J, Han, Y, Jiang, Y.
登録日	2021-01-18
公開日	2021-03-10
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (2.6 Å)
主引用文献	Structural mechanisms of gating and selectivity of human rod CNGA1 channel. Neuron, 109, 2021

7LFX

Cryo-EM structure of human cGMP-bound open CNGA1 channel in Na+/Ca2+
分子名称:	CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
著者	Xue, J, Han, Y, Jiang, Y.
登録日	2021-01-19
公開日	2021-03-10
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Structural mechanisms of gating and selectivity of human rod CNGA1 channel. Neuron, 109, 2021

7LFW

Cryo-EM structure of human cGMP-bound open CNGA1 channel in K+/Ca2+
分子名称:	CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
著者	Xue, J, Han, Y, Jiang, Y.
登録日	2021-01-18
公開日	2021-03-10
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Structural mechanisms of gating and selectivity of human rod CNGA1 channel. Neuron, 109, 2021

7LG1

Cryo-EM structure of human cGMP-bound CNGA1_E365Q channel in Na+/Ca2+
分子名称:	CALCIUM ION, CYCLIC GUANOSINE MONOPHOSPHATE, cGMP-gated cation channel alpha-1
著者	Xue, J, Han, Y, Jiang, Y.
登録日	2021-01-19
公開日	2021-03-10
最終更新日	2024-03-06
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	Structural mechanisms of gating and selectivity of human rod CNGA1 channel. Neuron, 109, 2021

8SGT

Cryo-EM structure of human NCX1 in Ca2+ bound, activated state (group II in the presence of 0.5 mM Ca2+)
分子名称:	CALCIUM ION, Fab heavy chain, Fab light chain, ...
著者	Xue, J, Jiang, Y.
登録日	2023-04-13
公開日	2023-10-11
最終更新日	2023-11-01
実験手法	ELECTRON MICROSCOPY (3.6 Å)
主引用文献	Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1. Nat Commun, 14, 2023

8SGJ

Cryo-EM structure of human NCX1 in apo inactivated state
分子名称:	CALCIUM ION, Fab heavy chain, Fab light chain, ...
著者	Xue, J, Jiang, Y.
登録日	2023-04-12
公開日	2023-10-11
最終更新日	2023-11-01
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Structural mechanisms of the human cardiac sodium-calcium exchanger NCX1. Nat Commun, 14, 2023

8SGI

Cryo-EM structure of human NCX1 in complex with SEA0400
分子名称:	2-{4-[(2,5-difluorophenyl)methoxy]phenoxy}-5-ethoxyaniline, CALCIUM ION, Fab heavy chain, ...
著者	Xue, J, Jiang, Y.
登録日	2023-04-12
公開日	2024-04-24
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Structural mechanisms of human cardiac sodium calcium exchanger NCX1 To Be Published

6O84

Cryo-EM structure of OTOP3 from xenopus tropicalis
分子名称:	LOC100127796 protein,LOC100127796 protein,OTOP3,LOC100127796 protein,LOC100127796 protein
著者	Chen, Q.F, Bai, X.C, Jiang, Y.X.
登録日	2019-03-08
公開日	2019-04-24
最終更新日	2024-03-20
実験手法	ELECTRON MICROSCOPY (3.92 Å)
主引用文献	Structural and functional characterization of an otopetrin family proton channel. Elife, 8, 2019

6O7C

Crystal structure of the LjCASTOR gating ring in the Ca2+ and K+ state
分子名称:	CALCIUM ION, Ion channel CASTOR, MAGNESIUM ION, ...
著者	Jiang, Y, Kim, S.
登録日	2019-03-07
公開日	2019-09-11
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Ca2+-regulated Ca2+channels with an RCK gating ring control plant symbiotic associations. Nat Commun, 10, 2019

6O7A

Crystal structure of the LjCASTOR gating ring in the Ca2+-free state
分子名称:	Ion channel CASTOR
著者	Jiang, Y, Kim, S.
登録日	2019-03-07
公開日	2019-09-11
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Ca2+-regulated Ca2+channels with an RCK gating ring control plant symbiotic associations. Nat Commun, 10, 2019

6O5B

Monomer of a cation channel
分子名称:	CALCIUM ION, Calcium uniporter protein, mitochondrial, ...
著者	Wang, Y, Bai, X, Jiang, Y.
登録日	2019-03-01
公開日	2019-05-22
最終更新日	2024-03-20
実験手法	ELECTRON MICROSCOPY (3.6 Å)
主引用文献	Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter. Cell, 177, 2019

6PFJ

Structure of S. venezuelae RsiG-WhiG-(ci-di-GMP) complex, P64 crystal form
分子名称:	9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor
著者	Schumacher, M.A.
登録日	2019-06-21
公開日	2019-11-13
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.08 Å)
主引用文献	c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces. Mol.Cell, 77, 2020

6P5R

Structure of T. brucei MERS1-GDP complex
分子名称:	GUANOSINE-5'-DIPHOSPHATE, Mitochondrial edited mRNA stability factor 1
著者	Schumacher, M.A.
登録日	2019-05-30
公開日	2019-11-06
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.45 Å)
主引用文献	Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei. Rna, 26, 2020

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