5HXR
Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 2.5 mM Na+ and 10mM Ca2+
Summary for 5HXR
Entry DOI | 10.2210/pdb5hxr/pdb |
Related | 5HWX 5HWY 5HXC 5HXE 5HXH 5HXS 5HYA |
Descriptor | sodium,calcium exchanger, CALCIUM ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... (6 entities in total) |
Functional Keywords | na+/ca2+ exchange, calcium signalling, membrane transporter, induced conformational change, membrane protein |
Biological source | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) |
Cellular location | Cell membrane ; Multi-pass membrane protein : Q57556 |
Total number of polymer chains | 1 |
Total formula weight | 34884.28 |
Authors | Liao, J.,Jiang, Y.X.,Faraldo-Gomez, J.D. (deposition date: 2016-01-31, release date: 2016-05-11, Last modification date: 2023-11-08) |
Primary citation | Liao, J.,Marinelli, F.,Lee, C.,Huang, Y.,Faraldo-Gomez, J.D.,Jiang, Y. Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger Nat.Struct.Mol.Biol., 23:590-599, 2016 Cited by PubMed: 27183196DOI: 10.1038/nsmb.3230 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.463 Å) |
Structure validation
Download full validation report