5KJ7
 
 | | Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) - from XFEL diffraction | | 分子名称: | CALCIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... | | 著者 | Lyubimov, A.Y, Uervirojnangkoorn, M, Zhou, Q, Zhao, M, Sauter, N.K, Brewster, A.S, Weis, W.I, Brunger, A.T. | | 登録日 | 2016-06-17 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex.
Elife, 5, 2016
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5KJ8
 | | Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) - from synchrotron diffraction | | 分子名称: | CALCIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... | | 著者 | Lyubimov, A.Y, Uervirojnangkoorn, M, Zhou, Q, Zhao, M, Sauter, N.K, Brewster, A.S, Weis, W.I, Brunger, A.T. | | 登録日 | 2016-06-17 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex.
Elife, 5, 2016
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5KTI
 | | Structure of cow mincle complexed with KMJ1 | | 分子名称: | 2,3-dimethoxybenzoic acid, CALCIUM ION, TRIETHYLENE GLYCOL, ... | | 著者 | Feinberg, H, Rambaruth, N.D.S, Jegouzo, S.A.F, Jacobsen, K.M, Djurhuus, R, Poulsen, T.B, Taylor, M.E, Drickamer, K, Weis, W.I. | | 登録日 | 2016-07-11 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Binding Sites for Acylated Trehalose Analogs of Glycolipid Ligands on an Extended Carbohydrate Recognition Domain of the Macrophage Receptor Mincle.
J.Biol.Chem., 291, 2016
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2FO0
 | | Organization of the SH3-SH2 Unit in Active and Inactive Forms of the c-Abl Tyrosine Kinase | | 分子名称: | 6-(2,6-DICHLOROPHENYL)-2-{[3-(HYDROXYMETHYL)PHENYL]AMINO}-8-METHYLPYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, GLYCEROL, MYRISTIC ACID, ... | | 著者 | Nagar, B, Hantschel, O, Seeliger, M, Davies, J.M, Weis, W.I, Superti-Furga, G, Kuriyan, J. | | 登録日 | 2006-01-12 | | 公開日 | 2006-03-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.
Mol.Cell, 21, 2006
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3UON
 | | Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist | | 分子名称: | (3R)-1-azabicyclo[2.2.2]oct-3-yl hydroxy(diphenyl)acetate, CHLORIDE ION, Human M2 muscarinic acetylcholine, ... | | 著者 | Haga, K, Kruse, A.C, Asada, H, Yurugi-Kobayashi, T, Shiroishi, M, Zhang, C, Weis, W.I, Okada, T, Kobilka, B.K, Haga, T, Kobayashi, T. | | 登録日 | 2011-11-16 | | 公開日 | 2012-02-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Nature, 482, 2012
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3VW7
 | | Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Proteinase-activated receptor 1, ... | | 著者 | Zhang, C, Srinivasan, Y, Arlow, D.H, Fung, J.J, Palmer, D, Zheng, Y, Green, H.F, Pandey, A, Dror, R.O, Shaw, D.E, Weis, W.I, Coughlin, S.R, Kobilka, B.K. | | 登録日 | 2012-08-07 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | High-resolution crystal structure of human protease-activated receptor 1
Nature, 492, 2012
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2KMB
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5DZZ
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5H5M
 | | Crystal structure of HMP-1 M domain | | 分子名称: | Alpha-catenin-like protein hmp-1 | | 著者 | Kang, H, Bang, I, Weis, W.I, Choi, H.J. | | 登録日 | 2016-11-08 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and functional characterization of Caenorhabditis elegans alpha-catenin reveals constitutive binding to beta-catenin and F-actin
J. Biol. Chem., 292, 2017
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4KMB
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3IFQ
 | | Interction of plakoglobin and beta-catenin with desmosomal cadherins | | 分子名称: | E-cadherin, SULFATE ION, plakoglobin | | 著者 | Choi, H.-J, Gross, J.C, Pokutta, S, Weis, W.I. | | 登録日 | 2009-07-24 | | 公開日 | 2009-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Interactions of plakoglobin and beta-catenin with desmosomal cadherins: basis of selective exclusion of alpha- and beta-catenin from desmosomes.
J.Biol.Chem., 284, 2009
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3JQH
 | | Structure of the neck region of the glycan-binding receptor DC-SIGNR | | 分子名称: | C-type lectin domain family 4 member M | | 著者 | Feinberg, H, Tso, C.K.W, Taylor, M.E, Drickamer, K, Weis, W.I. | | 登録日 | 2009-09-06 | | 公開日 | 2009-11-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Segmented helical structure of the neck region of the glycan-binding receptor DC-SIGNR.
J.Mol.Biol., 394, 2009
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3KJ6
 | | Crystal structure of a Methylated beta2 Adrenergic Receptor-Fab complex | | 分子名称: | Beta-2 adrenergic receptor, Fab heavy chain, Fab light chain, ... | | 著者 | Bokoch, M.P, Zou, Y, Rasmussen, S.G.F, Liu, C.W, Nygaard, R, Rosenbaum, D.M, Fung, J.J, Choi, H.-J, Thian, F.S, Kobilka, T.S, Puglisi, J.D, Weis, W.I, Pardo, L, Prosser, S, Mueller, L, Kobilka, B.K. | | 登録日 | 2009-11-02 | | 公開日 | 2010-02-16 | | 最終更新日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature, 463, 2010
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3KQG
 | | Trimeric Structure of Langerin | | 分子名称: | C-type lectin domain family 4 member K, CALCIUM ION | | 著者 | Feinberg, H, Powlesland, A.S, Taylor, M.E, Weis, W.I. | | 登録日 | 2009-11-17 | | 公開日 | 2010-02-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Trimeric structure of langerin.
J.Biol.Chem., 285, 2010
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6DDE
 | | Mu Opioid Receptor-Gi Protein Complex | | 分子名称: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Koehl, A, Hu, H, Maeda, S, Manglik, A, Zhang, Y, Kobilka, B.K, Skiniotis, G, Weis, W.I. | | 登録日 | 2018-05-10 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of the mu-opioid receptor-Giprotein complex.
Nature, 558, 2018
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6DDF
 | | Mu Opioid Receptor-Gi Protein Complex | | 分子名称: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Koehl, A, Hu, H, Maeda, S, Manglik, A, Kobilka, B.K, Skiniotis, G, Weis, W.I. | | 登録日 | 2018-05-10 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of the mu-opioid receptor-Giprotein complex.
Nature, 558, 2018
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5VYB
 | | Structure of the carbohydrate recognition domain of Dectin-2 complexed with a mammalian-type high mannose Man9GlcNAc2 oligosaccharide | | 分子名称: | C-type lectin domain family 6 member A, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Feinberg, H, Jegouzo, S.A.F, Rex, M.J, Drickamer, K, Taylor, M.E, Weis, W.I. | | 登録日 | 2017-05-24 | | 公開日 | 2017-07-05 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mechanism of pathogen recognition by human dectin-2.
J. Biol. Chem., 292, 2017
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5XA5
 | | Crystal structure of HMP-1-HMP-2 complex | | 分子名称: | Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2 | | 著者 | Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J. | | 登録日 | 2017-03-11 | | 公開日 | 2017-08-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface.
J.Biol.Chem., 292, 2017
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5X7D
 | | Structure of beta2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist | | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Liu, X, Ahn, S, Kahsai, A.W, Meng, K.-C, Latorraca, N.R, Pani, B, Venkatakrishnan, A.J, Masoudi, A, Weis, W.I, Dror, R.O, Chen, X, Lefkowitz, R.J, Kobilka, B.K. | | 登録日 | 2017-02-25 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | | 主引用文献 | Mechanism of intracellular allosteric beta 2AR antagonist revealed by X-ray crystal structure.
Nature, 548, 2017
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1I7W
 | | BETA-CATENIN/PHOSPHORYLATED E-CADHERIN COMPLEX | | 分子名称: | BETA-CATENIN, CHLORIDE ION, EPITHELIAL-CADHERIN, ... | | 著者 | Huber, A.H, Weis, W.I. | | 登録日 | 2001-03-10 | | 公開日 | 2001-05-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
Cell(Cambridge,Mass.), 105, 2001
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2OAJ
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1JPP
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2R4S
 | | Crystal structure of the human beta2 adrenoceptor | | 分子名称: | Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ... | | 著者 | Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K. | | 登録日 | 2007-08-31 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Nature, 450, 2007
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2R4R
 | | Crystal structure of the human beta2 adrenoceptor | | 分子名称: | Beta-2 adrenergic receptor, antibody for beta2 adrenoceptor, heavy chain, ... | | 著者 | Rasmussen, S.G.F, Choi, H.J, Rosenbaum, D.M, Kobilka, T.S, Thian, F.S, Edwards, P.C, Burghammer, M, Ratnala, V.R, Sanishvili, R, Fischetti, R.F, Schertler, G.F, Weis, W.I, Kobilka, B.K. | | 登録日 | 2007-08-31 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.
Nature, 450, 2007
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3BCT
 | | THE ARMADILLO REPEAT REGION FROM MURINE BETA-CATENIN | | 分子名称: | BETA-CATENIN, CHLORIDE ION, UREA | | 著者 | Huber, A.H, Nelson, W.J, Weis, W.I. | | 登録日 | 1997-07-31 | | 公開日 | 1997-11-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three-dimensional structure of the armadillo repeat region of beta-catenin.
Cell(Cambridge,Mass.), 90, 1997
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