5VYB

Structure of the carbohydrate recognition domain of Dectin-2 complexed with a mammalian-type high mannose Man9GlcNAc2 oligosaccharide

Summary for 5VYB

• Entry DOI: 10.2210/pdb5vyb/pdb
• Descriptor: C-type lectin domain family 6 member A, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: carbohydrate-binding protein; lectin; glycoprotein, sugar binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 18313.18

Authors

Feinberg, H.,Jegouzo, S.A.F.,Rex, M.J.,Drickamer, K.,Taylor, M.E.,Weis, W.I. (deposition date: 2017-05-24, release date: 2017-07-05, Last modification date: 2023-10-04)

• Primary citation: Feinberg, H.,Jegouzo, S.A.F.,Rex, M.J.,Drickamer, K.,Weis, W.I.,Taylor, M.E.; Mechanism of pathogen recognition by human dectin-2.; J. Biol. Chem., 292:13402-13414, 2017; PubMed: 28652405; DOI: 10.1074/jbc.M117.799080

Experimental method

X-RAY DIFFRACTION (2.4 Å)