5VYB
Structure of the carbohydrate recognition domain of Dectin-2 complexed with a mammalian-type high mannose Man9GlcNAc2 oligosaccharide
Summary for 5VYB
Entry DOI | 10.2210/pdb5vyb/pdb |
Descriptor | C-type lectin domain family 6 member A, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | carbohydrate-binding protein; lectin; glycoprotein, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 18313.18 |
Authors | Feinberg, H.,Jegouzo, S.A.F.,Rex, M.J.,Drickamer, K.,Taylor, M.E.,Weis, W.I. (deposition date: 2017-05-24, release date: 2017-07-05, Last modification date: 2023-10-04) |
Primary citation | Feinberg, H.,Jegouzo, S.A.F.,Rex, M.J.,Drickamer, K.,Weis, W.I.,Taylor, M.E. Mechanism of pathogen recognition by human dectin-2. J. Biol. Chem., 292:13402-13414, 2017 Cited by PubMed: 28652405DOI: 10.1074/jbc.M117.799080 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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