7F8Y
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![BU of 7f8y by Molmil](/molmil-images/mine/7f8y) | Crystal structure of the cholecystokinin receptor CCKAR in complex with devazepide | 分子名称: | N-[(3S)-1-methyl-2-oxidanylidene-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide, fusion protein of Cholecystokinin receptor type A and Endolysin | 著者 | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | 登録日 | 2021-07-02 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8U
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![BU of 7f8u by Molmil](/molmil-images/mine/7f8u) | Crystal structure of the cholecystokinin receptor CCKAR in complex with lintitript | 分子名称: | 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]ethanoic acid, Fusion protein of Cholecystokinin receptor type A and Endolysin | 著者 | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | 登録日 | 2021-07-02 | 公開日 | 2021-10-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8V
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![BU of 7f8v by Molmil](/molmil-images/mine/7f8v) | Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gi | 分子名称: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | 登録日 | 2021-07-02 | 公開日 | 2021-10-13 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8W
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![BU of 7f8w by Molmil](/molmil-images/mine/7f8w) | Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gq | 分子名称: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | 登録日 | 2021-07-02 | 公開日 | 2021-10-13 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8X
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![BU of 7f8x by Molmil](/molmil-images/mine/7f8x) | Crystal structure of the cholecystokinin receptor CCKAR in complex with NN9056 | 分子名称: | ASP-SMF-NLE-GLY-TRP-NLE-OEM-MEA-NH2 (NN9056), Cholecystokinin receptor type A,Endolysin | 著者 | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | 登録日 | 2021-07-02 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7E9G
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![BU of 7e9g by Molmil](/molmil-images/mine/7e9g) | Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu2 | 分子名称: | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one, DN13, ... | 著者 | Lin, S, Han, S, Zhao, Q, Wu, B. | 登録日 | 2021-03-04 | 公開日 | 2021-06-23 | 最終更新日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of G i -bound metabotropic glutamate receptors mGlu2 and mGlu4. Nature, 594, 2021
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7E9H
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![BU of 7e9h by Molmil](/molmil-images/mine/7e9h) | Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu4 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-3, ... | 著者 | Lin, S, Han, S, Zhao, Q, Wu, B. | 登録日 | 2021-03-04 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of G i -bound metabotropic glutamate receptors mGlu2 and mGlu4. Nature, 594, 2021
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7EPC
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![BU of 7epc by Molmil](/molmil-images/mine/7epc) | Cryo-EM structure of inactive mGlu7 homodimer | 分子名称: | Isoform 3 of Metabotropic glutamate receptor 7 | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
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7EPB
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![BU of 7epb by Molmil](/molmil-images/mine/7epb) | Cryo-EM structure of LY354740-bound mGlu2 homodimer | 分子名称: | (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, Anti-RON nanobody, Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
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7EPA
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![BU of 7epa by Molmil](/molmil-images/mine/7epa) | Cryo-EM structure of inactive mGlu2 homodimer | 分子名称: | Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
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7EPF
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![BU of 7epf by Molmil](/molmil-images/mine/7epf) | Crystal structure of mGlu2 bound to NAM597 | 分子名称: | (8~{R})-4-[2,4-bis(fluoranyl)phenyl]-8-methyl-7-[(2-methylpyrazol-3-yl)methyl]-6,8-dihydro-5~{H}-1,7-naphthyridine-2-carboxamide, FLAVIN MONONUCLEOTIDE, Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Lin, S, Han, S, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
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7EPD
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![BU of 7epd by Molmil](/molmil-images/mine/7epd) | Cryo-EM structure of inactive mGlu2-7 heterodimer | 分子名称: | Isoform 3 of Metabotropic glutamate receptor 7, Metabotropic glutamate receptor 2,Peptidylprolyl isomerase | 著者 | Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2021-07-07 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
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7EPE
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![BU of 7epe by Molmil](/molmil-images/mine/7epe) | Crystal structure of mGlu2 bound to NAM563 | 分子名称: | 4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide, FLAVIN MONONUCLEOTIDE, Metabotropic glutamate receptor 2 | 著者 | Du, J, Wang, D, Lin, S, Han, S, Wu, B, Zhao, Q. | 登録日 | 2021-04-26 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature, 594, 2021
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2TIO
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![BU of 2tio by Molmil](/molmil-images/mine/2tio) | LOW PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE | 分子名称: | BENZAMIDINE, CALCIUM ION, HEXANE, ... | 著者 | Huang, Q, Zhu, G, Tang, Q. | 登録日 | 1998-09-23 | 公開日 | 1998-09-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | X-ray studies on two forms of bovine beta-trypsin crystals in neat cyclohexane. Biochim.Biophys.Acta, 1429, 1998
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3I60
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![BU of 3i60 by Molmil](/molmil-images/mine/3i60) | |
8H5Y
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![BU of 8h5y by Molmil](/molmil-images/mine/8h5y) | Crystal structure of RadD- ADP complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative DNA repair helicase RadD, ... | 著者 | Yan, X.X, Tian, L.F. | 登録日 | 2022-10-14 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7001 Å) | 主引用文献 | Biochemical and Structural Analyses Shed Light on the Mechanisms of RadD DNA Binding and Its ATPase from Escherichia coli. Int J Mol Sci, 24, 2023
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3I4B
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![BU of 3i4b by Molmil](/molmil-images/mine/3i4b) | Crystal structure of GSK3b in complex with a pyrimidylpyrrole inhibitor | 分子名称: | Glycogen synthase kinase-3 beta, N-[(1S)-2-hydroxy-1-phenylethyl]-4-[5-methyl-2-(phenylamino)pyrimidin-4-yl]-1H-pyrrole-2-carboxamide | 著者 | Ter Haar, E. | 登録日 | 2009-07-01 | 公開日 | 2010-01-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control. J.Med.Chem., 52, 2009
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8H5Z
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![BU of 8h5z by Molmil](/molmil-images/mine/8h5z) | Crystal structure of RadD/ATP analogue complex | 分子名称: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Putative DNA repair helicase RadD, ZINC ION | 著者 | Yan, X.X, Tian, L.F. | 登録日 | 2022-10-14 | 公開日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.00002718 Å) | 主引用文献 | Biochemical and Structural Analyses Shed Light on the Mechanisms of RadD DNA Binding and Its ATPase from Escherichia coli. Int J Mol Sci, 24, 2023
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3I5Z
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![BU of 3i5z by Molmil](/molmil-images/mine/3i5z) | |
7LT6
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![BU of 7lt6 by Molmil](/molmil-images/mine/7lt6) | |
7LSW
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![BU of 7lsw by Molmil](/molmil-images/mine/7lsw) | |
8F5U
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![BU of 8f5u by Molmil](/molmil-images/mine/8f5u) | Rabbit muscle pyruvate kinase in complex with magnesium, potassium and pyruvate | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | 著者 | Holyoak, T, Fenton, A.W. | 登録日 | 2022-11-15 | 公開日 | 2023-05-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | PYK-SubstitutionOME: an integrated database containing allosteric coupling, ligand affinity and mutational, structural, pathological, bioinformatic and computational information about pyruvate kinase isozymes. Database (Oxford), 2023, 2023
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8F5T
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![BU of 8f5t by Molmil](/molmil-images/mine/8f5t) | Rabbit muscle pyruvate kinase in complex with sodium and magnesium | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... | 著者 | Holyoak, T, Fenton, A.W. | 登録日 | 2022-11-15 | 公開日 | 2023-05-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | PYK-SubstitutionOME: an integrated database containing allosteric coupling, ligand affinity and mutational, structural, pathological, bioinformatic and computational information about pyruvate kinase isozymes. Database (Oxford), 2023, 2023
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8F6M
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![BU of 8f6m by Molmil](/molmil-images/mine/8f6m) | Complex of Rabbit muscle pyruvate kinase with ADP and the phosphonate analogue of PEP mimicking the Michaelis complex. | 分子名称: | (E)-2-METHYL-3-PHOSPHONOACRYLATE, ADENOSINE-5'-DIPHOSPHATE, ALANINE, ... | 著者 | Holyoak, T, Fenton, A.W. | 登録日 | 2022-11-16 | 公開日 | 2023-05-24 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | PYK-SubstitutionOME: an integrated database containing allosteric coupling, ligand affinity and mutational, structural, pathological, bioinformatic and computational information about pyruvate kinase isozymes. Database (Oxford), 2023, 2023
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1Z09
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![BU of 1z09 by Molmil](/molmil-images/mine/1z09) | Solution structure of km23 | 分子名称: | Dynein light chain 2A, cytoplasmic | 著者 | Ilangovan, U, Ding, W, Mulder, K, Hinck, A.P, Zuniga, J, Trbovich, J.A, Demeler, B, Groppe, J.C. | 登録日 | 2005-03-01 | 公開日 | 2005-08-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and Dynamics of the Homodimeric Dynein Light Chain km23. J.Mol.Biol., 352 (2), 2005
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