7E9G

Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu2

Summary for 7E9G

• Entry DOI: 10.2210/pdb7e9g/pdb
• EMDB information: 31031
• Descriptor: Metabotropic glutamate receptor 2, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (8 entities in total)
• Functional Keywords: mglu2, gpcr, cryo-em, complex, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 322899.27

Authors

Lin, S.,Han, S.,Zhao, Q.,Wu, B. (deposition date: 2021-03-04, release date: 2021-06-23, Last modification date: 2021-08-04)

• Primary citation: Lin, S.,Han, S.,Cai, X.,Tan, Q.,Zhou, K.,Wang, D.,Wang, X.,Du, J.,Yi, C.,Chu, X.,Dai, A.,Zhou, Y.,Chen, Y.,Zhou, Y.,Liu, H.,Liu, J.,Yang, D.,Wang, M.W.,Zhao, Q.,Wu, B.; Structures of G i -bound metabotropic glutamate receptors mGlu2 and mGlu4.; Nature, 594:583-588, 2021; PubMed: 34135510; DOI: 10.1038/s41586-021-03495-2

Experimental method

ELECTRON MICROSCOPY (3.5 Å)