8QXA
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![BU of 8qxa by Molmil](/molmil-images/mine/8qxa) | TDP-43 amyloid fibrils: Morphology-1b | 分子名称: | TAR DNA-binding protein 43 | 著者 | Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. | 登録日 | 2023-10-24 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
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3IQX
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![BU of 3iqx by Molmil](/molmil-images/mine/3iqx) | ADP complex of C.therm. Get3 in closed form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Tail-anchored protein targeting factor Get3, ... | 著者 | Bozkurt, G, Wild, K, Sinning, I. | 登録日 | 2009-08-21 | 公開日 | 2009-12-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proc.Natl.Acad.Sci.USA, 106, 2009
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3IQW
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![BU of 3iqw by Molmil](/molmil-images/mine/3iqw) | AMPPNP complex of C. therm. Get3 | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Tail-anchored protein targeting factor Get3, ... | 著者 | Bozkurt, G, Wild, K, Sinning, I. | 登録日 | 2009-08-21 | 公開日 | 2009-12-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural insights into tail-anchored protein binding and membrane insertion by Get3. Proc.Natl.Acad.Sci.USA, 106, 2009
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3LPZ
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![BU of 3lpz by Molmil](/molmil-images/mine/3lpz) | Crystal structure of C. therm. Get4 | 分子名称: | Uncharacterized protein | 著者 | Bozkurt, G, Wild, K, Sinning, I. | 登録日 | 2010-02-08 | 公開日 | 2010-03-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | The structure of Get4 reveals an alpha-solenoid fold adapted for multiple interactions in tail-anchored protein biogenesis. Febs Lett., 584, 2010
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2RD0
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![BU of 2rd0 by Molmil](/molmil-images/mine/2rd0) | Structure of a human p110alpha/p85alpha complex | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Huang, C, Gabelli, S.B, Amzel, L.M. | 登録日 | 2007-09-20 | 公開日 | 2007-12-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations. Science, 318, 2007
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4PVK
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![BU of 4pvk by Molmil](/molmil-images/mine/4pvk) | Phl p 4 I153V N158H variant, a glucose oxidase | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, ... | 著者 | Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. | 登録日 | 2014-03-17 | 公開日 | 2014-04-02 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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4PVH
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![BU of 4pvh by Molmil](/molmil-images/mine/4pvh) | Phl p 4 N158H variant, a glucose dehydrogenase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Pollen allergen Phl p 4.0202, ... | 著者 | Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. | 登録日 | 2014-03-17 | 公開日 | 2014-04-02 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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4PWB
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![BU of 4pwb by Molmil](/molmil-images/mine/4pwb) | Phl p 4 I153V variant, a glucose oxidase, pressurized with Xenon | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Pollen allergen Phl p 4.0202, ... | 著者 | Zafred, D, Keller, W, Macheroux, P. | 登録日 | 2014-03-19 | 公開日 | 2014-04-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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4PVE
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![BU of 4pve by Molmil](/molmil-images/mine/4pve) | Wild-type Phl p 4.0202, a glucose dehydrogenase | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, ... | 著者 | Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. | 登録日 | 2014-03-17 | 公開日 | 2014-04-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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4PWC
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![BU of 4pwc by Molmil](/molmil-images/mine/4pwc) | Phl p 4 I153V N158H variant, a glucose oxidase, 3.5 M NaBr soak | 分子名称: | BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Pollen allergen Phl p 4.0202, ... | 著者 | Zafred, D, Keller, W, Macheroux, P. | 登録日 | 2014-03-19 | 公開日 | 2014-04-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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4PVJ
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![BU of 4pvj by Molmil](/molmil-images/mine/4pvj) | Phl p 4 I153V variant, a glucose oxidase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Pollen allergen Phl p 4.0202, ... | 著者 | Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. | 登録日 | 2014-03-17 | 公開日 | 2014-04-02 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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1TUP
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![BU of 1tup by Molmil](/molmil-images/mine/1tup) | TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA | 分子名称: | DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR ), ... | 著者 | Cho, Y, Gorina, S, Jeffrey, P.D, Pavletich, N.P. | 登録日 | 1995-07-11 | 公開日 | 1995-07-11 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. Science, 265, 1994
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1RQC
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![BU of 1rqc by Molmil](/molmil-images/mine/1rqc) | Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design | 分子名称: | COBALT (II) ION, formylmethionine deformylase | 著者 | Robien, M.A, Nguyen, K.T, Kumar, A, Hirsh, I, Turley, S, Pei, D, Hol, W.G. | 登録日 | 2003-12-04 | 公開日 | 2004-01-20 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An improved crystal form of Plasmodium falciparum peptide deformylase Protein Sci., 13, 2004
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8DVG
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![BU of 8dvg by Molmil](/molmil-images/mine/8dvg) | Structure of KRAS WT(7-16)-HLA-A*03:01 | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, HLA class I histocompatibility antigen, ... | 著者 | Wright, K.M, Miller, M, Gabelli, S.B. | 登録日 | 2022-07-28 | 公開日 | 2023-07-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | 主引用文献 | Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
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7KGU
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![BU of 7kgu by Molmil](/molmil-images/mine/7kgu) | Structure of 2Q1-Fab, an antibody selective for IDH2R140Q-HLA-B*07:02 | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Miller, M.S, Aytenfisu, T.Y, Wright, K.M, Gabelli, S.B. | 登録日 | 2020-10-18 | 公開日 | 2021-06-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nat Commun, 12, 2021
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7STF
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![BU of 7stf by Molmil](/molmil-images/mine/7stf) | Structure of KRAS G12V/HLA-A*03:01 in complex with antibody fragment V2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | 著者 | Wright, K.M, Gabelli, S.B, Miller, M. | 登録日 | 2021-11-12 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
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5T7F
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![BU of 5t7f by Molmil](/molmil-images/mine/5t7f) | PI3Kdelta in complex with the inhibitor GS-643624 | 分子名称: | 2,4-bis(azanyl)-6-[[(1~{S})-1-[5-chloranyl-3-(5-fluoranyl-4-methyl-pyridin-3-yl)-4-oxidanylidene-quinazolin-2-yl]ethyl]amino]pyrimidine-5-carbonitrile, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 著者 | Somoza, J.R, Villasenor, A. | 登録日 | 2016-09-04 | 公開日 | 2016-12-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Discovery of GS-9901: A Potent, Selective and Metabolically Stable Inhibitor of PI3Kd To Be Published
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5T8I
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![BU of 5t8i by Molmil](/molmil-images/mine/5t8i) | PI3Kdelta in complex with the inhibitor GS-9901 | 分子名称: | 2,4-diamino-6-{[(S)-[5-chloro-8-fluoro-4-oxo-3-(pyridin-3-yl)-3,4-dihydroquinazolin-2-yl](cyclopropyl)methyl]amino}pyrimidine-5-carbonitrile, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 著者 | Somoza, J.R, Villasenor, A. | 登録日 | 2016-09-07 | 公開日 | 2016-12-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The Discovery of GS-9901: A Potent, Selective and Metabolically Stable Inhibitor of PI3Kd To Be Published
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