8EFQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8efq by Molmil](/molmil-images/mine/8efq) | DAMGO-bound mu-opioid receptor-Gi complex | 分子名称: | DAMGO, ETHANOLAMINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhuang, Y, Wang, Y, Guo, S, Zhou, X.E, Rao, Q, He, X, He, B, Liu, J, Zhou, Q, Wang, X, Liu, W, Jiang, X, Yang, D, Chen, X, Jiang, Y, Jiang, H, Shen, J, Melcher, K, Wang, M, Xie, X, Xu, H.E. | 登録日 | 2022-09-08 | 公開日 | 2022-11-09 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular recognition of morphine and fentanyl by the human mu-opioid receptor. Cell, 185, 2022
|
|
6Z18
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6z18 by Molmil](/molmil-images/mine/6z18) | Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; R32 form | 分子名称: | RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG | 著者 | Ruszkowski, M, Sekula, B, Mao, S, Haruehanroengra, P, Sheng, J. | 登録日 | 2020-05-12 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA. Nucleic Acids Res., 48, 2020
|
|
4X80
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x80 by Molmil](/molmil-images/mine/4x80) | Crystal Structure of murine 7B4 Fab monoclonal antibody against ADAMTS5 | 分子名称: | IgG1 7B4 FAB Heavy chain, IgG1 7B4 FAB Light Chain | 著者 | Larkin, J, Lohr, T.A, Elefante, L, Shearin, J, Matico, R, Su, J.-L, Xue, Y, Liu, F, Genell, C, Miller, R.E, Tran, P.B, Malfait, A.-M, Maier, C.C, Matheny, C.J. | 登録日 | 2014-12-09 | 公開日 | 2015-04-08 | 最終更新日 | 2015-08-05 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthr. Cartil., 23, 2015
|
|
4X8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x8j by Molmil](/molmil-images/mine/4x8j) | Crystal Structure of murine 12F4 Fab monoclonal antibody against ADAMTS5 | 分子名称: | 12F4 FAB Heavy chain, 12F4 FAB Light chain, NONAETHYLENE GLYCOL, ... | 著者 | Larkin, J, Lohr, T.A, Elefante, L, Shearin, J, Matico, R, Su, J.-L, Xue, Y, Liu, F, Genell, C, Miller, R.E, Tran, P.B, Malfait, A.-M, Maier, C.C, Matheny, C.J. | 登録日 | 2014-12-10 | 公開日 | 2015-04-08 | 最終更新日 | 2015-08-05 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthr. Cartil., 23, 2015
|
|
7OUO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ouo by Molmil](/molmil-images/mine/7ouo) | Crystal structure of RNA duplex [UCGUGCGA]2 in complex with Ba2+ cation | 分子名称: | BARIUM ION, RNA (5'-R(*UP*CP*GP*UP*GP*CP*GP*A)-3') | 著者 | Ruszkowski, M, Mao, S, Zheng, Y.Y, Ruszkowska, A, Sheng, J. | 登録日 | 2021-06-12 | 公開日 | 2022-03-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.212 Å) | 主引用文献 | Structural Insights Into the 5'UG/3'GU Wobble Tandem in Complex With Ba 2+ Cation. Front Mol Biosci, 8, 2021
|
|
6WY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wy2 by Molmil](/molmil-images/mine/6wy2) | Crystal structure of RNA-10mer: CCGG(N4-methyl-C)GCCGG | 分子名称: | MAGNESIUM ION, POTASSIUM ION, RNA-10mer: CCGG(4-methyl-C)GCCGG | 著者 | Sekula, B, Ruszkowski, M, Mao, S, Haruehanroengra, P, Sheng, J. | 登録日 | 2020-05-12 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.928 Å) | 主引用文献 | Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA. Nucleic Acids Res., 48, 2020
|
|
6WY3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wy3 by Molmil](/molmil-images/mine/6wy3) | Crystal structure of RNA-10mer: CCGG(N4,N4-dimethyl-C)GCCGG; P212121 form | 分子名称: | RNA (5'-R(*CP*CP*GP*GP*(LV2)P*GP*CP*CP*GP*G)-3') | 著者 | Sekula, B, Ruszkowski, M, Mao, S, Haruehanroengra, P, Sheng, J. | 登録日 | 2020-05-12 | 公開日 | 2020-09-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.647 Å) | 主引用文献 | Base pairing, structural and functional insights into N4-methylcytidine (m4C) and N4,N4-dimethylcytidine (m42C) modified RNA. Nucleic Acids Res., 48, 2020
|
|
7BV2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bv2 by Molmil](/molmil-images/mine/7bv2) | The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP) | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
|
|
7BV1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7bv1 by Molmil](/molmil-images/mine/7bv1) | Cryo-EM structure of the apo nsp12-nsp7-nsp8 complex | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
|
|
5TDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tdk by Molmil](/molmil-images/mine/5tdk) | RNA decamer duplex with eight 2'-5'-linkages | 分子名称: | RNA (5'-R(*CP*CP*GP*GP*CP*GP*CP*CP*GP*G)-3'), STRONTIUM ION | 著者 | Luo, Z, Sheng, J. | 登録日 | 2016-09-19 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Structural insights into RNA duplexes with multiple 2 -5 -linkages. Nucleic Acids Res., 45, 2017
|
|
5H4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h4b by Molmil](/molmil-images/mine/5h4b) | Crystal structure of Cbln4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-4 | 著者 | Zhong, C, Shen, J, Zhang, H, Ding, J. | 登録日 | 2016-10-31 | 公開日 | 2017-09-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions. Cell Rep, 20, 2017
|
|
5TDJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tdj by Molmil](/molmil-images/mine/5tdj) | RNA decamer duplex with four 2'-5'-linkages | 分子名称: | RNA (5'-R(*CP*CP*GP*GP*CP*GP*CP*CP*GP*G)-3'), STRONTIUM ION | 著者 | Luo, Z, Sheng, J. | 登録日 | 2016-09-19 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insights into RNA duplexes with multiple 2 -5 -linkages. Nucleic Acids Res., 45, 2017
|
|
8JR9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jr9 by Molmil](/molmil-images/mine/8jr9) | Small molecule agonist (PCO371) bound to human parathyroid hormone receptor type 1 (PTH1R) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha-1, ... | 著者 | Zhao, L, He, Q, Yuan, Q, Gu, Y, He, X, Shan, H, Li, J, Wang, K, Li, Y, Hu, W, Wu, K, Shen, J, Xu, H.E. | 登録日 | 2023-06-16 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Conserved class B GPCR activation by a biased intracellular agonist. Nature, 621, 2023
|
|
8AP1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ap1 by Molmil](/molmil-images/mine/8ap1) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with two GTP molecules poised for de novo initiation (IC2) | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | 登録日 | 2022-08-09 | 公開日 | 2023-08-23 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
|
|
8ATV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8atv by Molmil](/molmil-images/mine/8atv) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 5-mer RNA, pppGpGpApApA (IC5) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase, mitochondrial, ... | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | 登録日 | 2022-08-24 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
|
|
8ATW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8atw by Molmil](/molmil-images/mine/8atw) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 6-mer RNA, pppGpGpApApApU (IC6) | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | 登録日 | 2022-08-24 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
|
|
8ATT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8att by Molmil](/molmil-images/mine/8att) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 4-mer RNA, pppGpGpUpA (IC4) | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | 登録日 | 2022-08-24 | 公開日 | 2023-08-30 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
|
|
8QX9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qx9 by Molmil](/molmil-images/mine/8qx9) | TDP-43 amyloid fibrils: Morphology-1a | 分子名称: | TAR DNA-binding protein 43 | 著者 | Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. | 登録日 | 2023-10-24 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
|
|
8QXB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qxb by Molmil](/molmil-images/mine/8qxb) | TDP-43 amyloid fibrils: Morphology-2 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. | 登録日 | 2023-10-24 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | 主引用文献 | Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
|
|
8QXA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8qxa by Molmil](/molmil-images/mine/8qxa) | TDP-43 amyloid fibrils: Morphology-1b | 分子名称: | TAR DNA-binding protein 43 | 著者 | Sharma, K, Shenoy, J, Loquet, A, Schmidt, M, Faendrich, M. | 登録日 | 2023-10-24 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (4.05 Å) | 主引用文献 | Cryo-EM observation of the amyloid key structure of polymorphic TDP-43 amyloid fibrils. Nat Commun, 15, 2024
|
|
4WM7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wm7 by Molmil](/molmil-images/mine/4wm7) | Crystal Structure of Human Enterovirus D68 in Complex with Pleconaril | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, VP1, VP2, ... | 著者 | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2014-10-08 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children. Science, 347, 2015
|
|
4WM8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wm8 by Molmil](/molmil-images/mine/4wm8) | Crystal Structure of Human Enterovirus D68 | 分子名称: | DECANOIC ACID, VP1, VP2, ... | 著者 | Liu, Y, Sheng, J, Fokine, A, Meng, G, Long, F, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2014-10-08 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Virus structure. Structure and inhibition of EV-D68, a virus that causes respiratory illness in children. Science, 347, 2015
|
|
5H48
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h48 by Molmil](/molmil-images/mine/5h48) | Crystal structure of Cbln1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | 著者 | Zhong, C, Shen, J, Zhang, H, Ding, J. | 登録日 | 2016-10-31 | 公開日 | 2017-09-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions. Cell Rep, 20, 2017
|
|
5H4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h4c by Molmil](/molmil-images/mine/5h4c) | Crystal structure of Cbln4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Cbln4 | 著者 | Zhong, C, Shen, J, Zhang, H, Ding, J. | 登録日 | 2016-10-31 | 公開日 | 2017-09-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions. Cell Rep, 20, 2017
|
|
5H49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5h49 by Molmil](/molmil-images/mine/5h49) | Crystal structure of Cbln1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | 著者 | Zhong, C, Shen, J, Zhang, H, Ding, J. | 登録日 | 2016-10-31 | 公開日 | 2017-09-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions. Cell Rep, 20, 2017
|
|