1UEL
 
 | | Solution structure of ubiquitin-like domain of hHR23B complexed with ubiquitin-interacting motif of proteasome subunit S5a | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 4, UV excision repair protein RAD23 homolog B | | 著者 | Fujiwara, K, Tenno, T, Jee, J.G, Sugasawa, K, Ohki, I, Kojima, C, Tochio, H, Hiroaki, H, Hanaoka, H, Shirakawa, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-05-19 | | 公開日 | 2004-02-10 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Ubiquitin-interacting Motif of S5a Bound to the Ubiquitin-like Domain of HR23B
J.Biol.Chem., 279, 2004
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6AHS
 | | Mouse Kallikrein 7 in complex with imidazolinylindole derivative | | 分子名称: | 1-[(2-chlorophenyl)sulfonyl]-5-methyl-3-[(4R)-2-methyl-4,5-dihydro-1H-imidazol-4-yl]-1H-indole, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Sugawara, H. | | 登録日 | 2018-08-20 | | 公開日 | 2019-01-02 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors.
Bioorg. Med. Chem. Lett., 29, 2019
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2SFA
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3WHB
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3WHC
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8GYH
 | | Crystal structure of Fic25 (apo form) from Streptomyces ficellus | | 分子名称: | DegT/DnrJ/EryC1/StrS family aminotransferase, GLYCEROL, IMIDAZOLE | | 著者 | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | | 登録日 | 2022-09-22 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis.
Acs Chem.Biol., 18, 2023
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8WWY
 | | Crystal structure of mouse TIFA/TIFAB heterodimer | | 分子名称: | (2R,5R)-hexane-2,5-diol, TRAF-interacting protein with FHA domain-containing protein A, TRAF-interacting protein with FHA domain-containing protein B | | 著者 | Nakamura, T. | | 登録日 | 2023-10-27 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA.
Proc.Natl.Acad.Sci.USA, 121, 2024
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2E2R
 | | Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol A | | 分子名称: | 4,4'-PROPANE-2,2-DIYLDIPHENOL, Estrogen-related receptor gamma, GLYCEROL | | 著者 | Matsushima, A, Kakuta, Y, Teramoto, T, Koshiba, T, Kimura, M, Shimohigashi, Y. | | 登録日 | 2006-11-16 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERR{gamma}
J.Biochem.(Tokyo), 142, 2007
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1BON
 | | THREE-DIMENSIONAL STRUCTURE OF BOMBYXIN-II, AN INSULIN-RELATED BRAIN-SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX MORI: COMPARISON WITH INSULIN AND RELAXIN | | 分子名称: | BOMBYXIN-II,BOMBYXIN A-2, BOMBYXIN-II,BOMBYXIN A-6 | | 著者 | Nagata, K, Hatanaka, H, Kohda, D, Inagaki, F, Structural Proteomics in Europe (SPINE) | | 登録日 | 1994-07-21 | | 公開日 | 1995-01-26 | | 最終更新日 | 2019-12-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J.Mol.Biol., 253, 1995
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3NG5
 | | Crystal Structure of V30M transthyretin complexed with (-)-epigallocatechin gallate (EGCG) | | 分子名称: | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, GLYCEROL, Transthyretin | | 著者 | Miyata, M, Nakamura, T, Ikemizu, S, Chirifu, M, Yamagata, Y, Kai, H. | | 登録日 | 2010-06-11 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of green tea polyphenol(-)-epigallocatechin gallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site
Biochemistry, 2010
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1BOM
 | | THREE-DIMENSIONAL STRUCTURE OF BOMBYXIN-II, AN INSULIN-RELATED BRAIN-SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX MORI: COMPARISON WITH INSULIN AND RELAXIN | | 分子名称: | BOMBYXIN-II,BOMBYXIN A-2, BOMBYXIN-II,BOMBYXIN A-6 | | 著者 | Nagata, K, Hatanaka, H, Kohda, D, Inagaki, F. | | 登録日 | 1994-07-21 | | 公開日 | 1994-11-01 | | 最終更新日 | 2019-12-25 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J.Mol.Biol., 253, 1995
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2CZQ
 | | A novel cutinase-like protein from Cryptococcus sp. | | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, cutinase-like protein | | 著者 | Masaki, K, Kamini, N.R, Ikeda, H, Iefuji, H, Kondo, H, Suzuki, M, Tsuda, S. | | 登録日 | 2005-07-14 | | 公開日 | 2006-07-14 | | 最終更新日 | 2012-06-13 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Crystal structure and enhanced activity of a cutinase-like enzyme from Cryptococcus sp. strain S-2
Proteins, 77, 2009
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1EHL
 | | 64M-2 ANTIBODY FAB COMPLEXED WITH D(5HT)(6-4)T | | 分子名称: | 5'-(D(5HT)P*(6-4)T)-3', ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (HEAVY CHAIN), ANTI-(6-4) PHOTOPRODUCT ANTIBODY 64M-2 FAB (LIGHT CHAIN) | | 著者 | Yokoyama, H, Mizutani, R, Satow, Y, Komatsu, Y, Ohtsuka, E, Nikaido, O. | | 登録日 | 2000-02-21 | | 公開日 | 2001-02-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation.
J.Mol.Biol., 299, 2000
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3ORN
 | | Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4987655 and MgAMP-PNP | | 分子名称: | 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-5-[(3-oxo-1,2-oxazinan-2-yl)methyl]benzamide, Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, ... | | 著者 | Lukacs, C.M, Janson, C, Schuck, V, Belunis, C. | | 登録日 | 2010-09-07 | | 公開日 | 2011-03-02 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent.
Bioorg.Med.Chem.Lett., 21, 2011
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3OS3
 | | Mitogen-activated protein kinase kinase 1 (MEK1) in complex with CH4858061 and MgATP | | 分子名称: | 2-[(4-ethynyl-2-fluorophenyl)amino]-3,4-difluoro-N-(2-hydroxyethoxy)-5-{[(2-hydroxyethoxy)imino]methyl}benzamide, ADENOSINE-5'-TRIPHOSPHATE, Dual specificity mitogen-activated protein kinase kinase 1, ... | | 著者 | Lukacs, C.M, Janson, C, Schuck, V, Belunis, C. | | 登録日 | 2010-09-08 | | 公開日 | 2011-07-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent.
Bioorg.Med.Chem.Lett., 21, 2011
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1TFA
 | | OVOTRANSFERRIN, N-TERMINAL LOBE, APO FORM | | 分子名称: | PROTEIN (OVOTRANSFERRIN), SULFATE ION | | 著者 | Mizutani, K, Yamashita, H, Mikami, B, Hirose, M. | | 登録日 | 1999-01-07 | | 公開日 | 1999-01-13 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Alternative structural state of transferrin. The crystallographic analysis of iron-loaded but domain-opened ovotransferrin N-lobe.
J.Biol.Chem., 274, 1999
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6JNO
 | | RXRa structure complexed with CU-6PMN | | 分子名称: | 7-oxidanyl-2-oxidanylidene-6-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)chromene-3-carboxylic acid, Retinoic acid receptor RXR-alpha | | 著者 | Kawasaki, M, Nakano, S, Motoyama, T, Yamada, S, Watanabe, M, Takamura, Y, Fujihara, M, Tokiwa, H, Kakuta, H, Ito, S. | | 登録日 | 2019-03-17 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening.
J.Med.Chem., 62, 2019
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1HMK
 | | RECOMBINANT GOAT ALPHA-LACTALBUMIN | | 分子名称: | CALCIUM ION, PROTEIN (ALPHA-LACTALBUMIN) | | 著者 | Horii, K, Matsushima, M, Tsumoto, K, Kumagai, I. | | 登録日 | 1998-11-26 | | 公開日 | 1999-11-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Effect of the extra n-terminal methionine residue on the stability and folding of recombinant alpha-lactalbumin expressed in Escherichia coli.
J.Mol.Biol., 285, 1999
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6E5F
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6E5D
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8GYI
 | | Crystal structure of Fic25 (holo form) from Streptomyces ficellus | | 分子名称: | DegT/DnrJ/EryC1/StrS family aminotransferase, GLYCEROL, IMIDAZOLE, ... | | 著者 | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | | 登録日 | 2022-09-22 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis.
Acs Chem.Biol., 18, 2023
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8GYJ
 | | Crystal structure of Fic25 complexed with PLP-(5S,6S)-N2-acetyl-DADH adduct from Streptomyces ficellus | | 分子名称: | (2~{S},5~{S},6~{S})-2-acetamido-6-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-5,7-bis(oxidanyl)heptanoic acid, DegT/DnrJ/EryC1/StrS family aminotransferase, GLYCEROL, ... | | 著者 | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | | 登録日 | 2022-09-22 | | 公開日 | 2023-02-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis.
Acs Chem.Biol., 18, 2023
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2YQS
 | | Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the product-binding form | | 分子名称: | GLYCEROL, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Miki, K, Maruyama, D, Nishitani, Y, Nonaka, T, Kita, A. | | 登録日 | 2007-03-30 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism
J.Biol.Chem., 282, 2007
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2YQJ
 | | Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the reaction-completed form | | 分子名称: | GLYCEROL, MAGNESIUM ION, SULFATE ION, ... | | 著者 | Miki, K, Maruyama, D, Nishitani, Y, Nonaka, T, Kita, A. | | 登録日 | 2007-03-30 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism
J.Biol.Chem., 282, 2007
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2YQC
 | | Crystal Structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the apo-like form | | 分子名称: | GLYCEROL, MAGNESIUM ION, UDP-N-acetylglucosamine pyrophosphorylase | | 著者 | Miki, K, Maruyama, D, Nishitani, Y, Nonaka, T, Kita, A. | | 登録日 | 2007-03-30 | | 公開日 | 2007-05-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism
J.Biol.Chem., 282, 2007
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