4G0O
 
 | | Crystal structure of Arabidopsis thaliana AGO5 MID domain | | 分子名称: | Protein argonaute 5, SULFATE ION | | 著者 | Frank, F, Hauver, J, Sonenberg, N, Nagar, B. | | 登録日 | 2012-07-09 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.186 Å) | | 主引用文献 | Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs.
Embo J., 31, 2012
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4G0M
 | | Crystal structure of Arabidopsis thaliana AGO2 MID domain | | 分子名称: | Protein argonaute 2, SULFATE ION | | 著者 | Frank, F, Hauver, J, Sonenberg, N, Nagar, B. | | 登録日 | 2012-07-09 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.306 Å) | | 主引用文献 | Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs.
Embo J., 31, 2012
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4G0Q
 | | Crystal structure of Arabidopsis thaliana AGO1 MID domain in complex with CMP | | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, Protein argonaute 1 | | 著者 | Frank, F, Hauver, J, Sonenberg, N, Nagar, B. | | 登録日 | 2012-07-09 | | 公開日 | 2012-07-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs.
Embo J., 31, 2012
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4HOR
 | | Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligocytidine | | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 5, MAGNESIUM ION, RNA (5'-R(*(CTP)P*CP*CP*CP*C)-3') | | 著者 | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | 登録日 | 2012-10-22 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.861 Å) | | 主引用文献 | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOU
 | | Crystal Structure of N-terminal Human IFIT1 | | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 1 | | 著者 | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | 登録日 | 2012-10-22 | | 公開日 | 2013-01-30 | | 最終更新日 | 2013-02-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOT
 | | Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligoadenine | | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 5, MAGNESIUM ION, RNA (5'-R(*(ATP)P*AP*AP*A)-3') | | 著者 | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | 登録日 | 2012-10-22 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOQ
 | | Crystal Structure of Full-Length Human IFIT5 | | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 5 | | 著者 | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | 登録日 | 2012-10-22 | | 公開日 | 2013-01-23 | | 最終更新日 | 2013-02-27 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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4HOS
 | | Crystal Structure of Full-Length Human IFIT5 with 5`-triphosphate Oligouridine | | 分子名称: | Interferon-induced protein with tetratricopeptide repeats 5, RNA (5'-R(*(UTP)P*UP*UP*U)-3'), SODIUM ION | | 著者 | Abbas, Y.M, Pichlmair, A, Gorna, M.W, Superti-Furga, G, Nagar, B. | | 登録日 | 2012-10-22 | | 公開日 | 2013-01-23 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins.
Nature, 494, 2013
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5UDJ
 | | IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA | | 分子名称: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(G3A))-R(P*AP*AP*A)-3'), ... | | 著者 | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | 登録日 | 2016-12-27 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5U85
 | | Murine saposin-D (SapD), open conformation | | 分子名称: | Saposin-D | | 著者 | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2016-12-13 | | 公開日 | 2018-06-13 | | 最終更新日 | 2019-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of saposin D in an open conformation.
J. Struct. Biol., 204, 2018
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5U84
 | | Acid ceramidase (ASAH1, aCDase) from common minke whale, Cys143Ala, uncleaved | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, ... | | 著者 | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2016-12-13 | | 公開日 | 2018-03-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Structural basis for the activation of acid ceramidase.
Nat Commun, 9, 2018
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5U7Z
 | | Human acid ceramidase (ASAH1, aCDase) self-activated | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid ceramidase, SULFATE ION, ... | | 著者 | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2016-12-13 | | 公開日 | 2018-03-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for the activation of acid ceramidase.
Nat Commun, 9, 2018
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5UDL
 | | IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap) | | 分子名称: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | | 著者 | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | 登録日 | 2016-12-27 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5UDY
 | | Human alkaline sphingomyelinase (alk-SMase, ENPP7, NPP7) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gorelik, A, Liu, F, Illes, K, Nagar, B. | | 登録日 | 2016-12-28 | | 公開日 | 2017-03-22 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the human alkaline sphingomyelinase provides insights into substrate recognition.
J. Biol. Chem., 292, 2017
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5VEM
 | | Human ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ectonucleotide pyrophosphatase/phosphodiesterase family member 5, ... | | 著者 | Gorelik, A, Randriamihaja, A, Illes, K, Nagar, B. | | 登録日 | 2017-04-05 | | 公開日 | 2017-09-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5.
FEBS J., 284, 2017
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5UDK
 | | IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | 登録日 | 2016-12-27 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5U81
 | | Acid ceramidase (ASAH1, aCDase) from naked mole rat, Cys143Ala, uncleaved | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid ceramidase isoform b, CHLORIDE ION, ... | | 著者 | Gebai, A, Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2016-12-13 | | 公開日 | 2018-03-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for the activation of acid ceramidase.
Nat Commun, 9, 2018
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5VEN
 | | Murine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ectonucleotide pyrophosphatase/phosphodiesterase family member 5, ... | | 著者 | Gorelik, A, Randriamihaja, A, Illes, K, Nagar, B. | | 登録日 | 2017-04-05 | | 公開日 | 2017-09-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5.
FEBS J., 284, 2017
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5VEO
 | | Murine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5), inactive (T72A), in complex with AMP | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... | | 著者 | Gorelik, A, Randriamihaja, A, Illes, K, Nagar, B. | | 登録日 | 2017-04-05 | | 公開日 | 2017-09-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5.
FEBS J., 284, 2017
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5W5H
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5W7E
 | | Murine acyloxyacyl hydrolase (AOAH), S262A mutant, with dimyristoyl phosphatidylcholine | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl ditetradecanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acyloxyacyl hydrolase, ... | | 著者 | Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2017-06-19 | | 公開日 | 2018-01-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5W78
 | | Human acyloxyacyl hydrolase (AOAH), proteolytically processed | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acyloxyacyl hydrolase, CALCIUM ION, ... | | 著者 | Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2017-06-19 | | 公開日 | 2018-01-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.271 Å) | | 主引用文献 | Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5W7A
 | | Rabbit acyloxyacyl hydrolase (AOAH), proteolytically processed, S262A mutant, with LPS (low quality saposin domain) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-HYDROXY-TETRADECANOIC ACID, ... | | 著者 | Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2017-06-19 | | 公開日 | 2018-01-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5W7D
 | | Murine acyloxyacyl hydrolase (AOAH), S262A mutant | | 分子名称: | 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gorelik, A, Illes, K, Nagar, B. | | 登録日 | 2017-06-19 | | 公開日 | 2018-01-03 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of the mammalian lipopolysaccharide detoxifier.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5UDI
 | | IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap) | | 分子名称: | CALCIUM ION, Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), ... | | 著者 | Abbas, Y.M, Martinez-Montero, S, Damha, M.J, Nagar, B. | | 登録日 | 2016-12-27 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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