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5VEO

Murine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5), inactive (T72A), in complex with AMP

Summary for 5VEO
Entry DOI10.2210/pdb5veo/pdb
Related5VEM 5VEN
DescriptorEctonucleotide pyrophosphatase/phosphodiesterase family member 5, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywordshydrolase
Biological sourceMus musculus (Mouse)
Total number of polymer chains1
Total formula weight51967.42
Authors
Gorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B. (deposition date: 2017-04-05, release date: 2017-09-20, Last modification date: 2020-07-29)
Primary citationGorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B.
A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5.
FEBS J., 284:3718-3726, 2017
Cited by
PubMed: 28898552
DOI: 10.1111/febs.14266
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.53 Å)
Structure validation

217705

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