5VEO
Murine ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5), inactive (T72A), in complex with AMP
Summary for 5VEO
Entry DOI | 10.2210/pdb5veo/pdb |
Related | 5VEM 5VEN |
Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total) |
Functional Keywords | hydrolase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 51967.42 |
Authors | Gorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B. (deposition date: 2017-04-05, release date: 2017-09-20, Last modification date: 2020-07-29) |
Primary citation | Gorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B. A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5. FEBS J., 284:3718-3726, 2017 Cited by PubMed: 28898552DOI: 10.1111/febs.14266 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.53 Å) |
Structure validation
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