5U84

Acid ceramidase (ASAH1, aCDase) from common minke whale, Cys143Ala, uncleaved

Summary for 5U84

• Entry DOI: 10.2210/pdb5u84/pdb
• Related: 5U7Z 5U81
• Descriptor: Acid ceramidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: ceramidase, ceramide, ntn-hydrolase, hydrolase
• Biological source: Balaenoptera acutorostrata (minke whale)
• Total number of polymer chains: 2
• Total formula weight: 98634.37

Authors

Gebai, A.,Gorelik, A.,Illes, K.,Nagar, B. (deposition date: 2016-12-13, release date: 2018-03-28, Last modification date: 2020-07-29)

• Primary citation: Gebai, A.,Gorelik, A.,Li, Z.,Illes, K.,Nagar, B.; Structural basis for the activation of acid ceramidase.; Nat Commun, 9:1621-1621, 2018; PubMed: 29692406; DOI: 10.1038/s41467-018-03844-2

Experimental method

X-RAY DIFFRACTION (2.34 Å)