5U81
Acid ceramidase (ASAH1, aCDase) from naked mole rat, Cys143Ala, uncleaved
Summary for 5U81
Entry DOI | 10.2210/pdb5u81/pdb |
Related | 5U7Z 5U84 |
Descriptor | Acid ceramidase isoform b, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | ceramidase, ceramide, ntn-hydrolase, hydrolase |
Biological source | Heterocephalus glaber (Naked mole rat) |
Total number of polymer chains | 1 |
Total formula weight | 47237.30 |
Authors | Gebai, A.,Gorelik, A.,Illes, K.,Nagar, B. (deposition date: 2016-12-13, release date: 2018-03-28, Last modification date: 2020-07-29) |
Primary citation | Gebai, A.,Gorelik, A.,Li, Z.,Illes, K.,Nagar, B. Structural basis for the activation of acid ceramidase. Nat Commun, 9:1621-1621, 2018 Cited by PubMed: 29692406DOI: 10.1038/s41467-018-03844-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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