5U84

Acid ceramidase (ASAH1, aCDase) from common minke whale, Cys143Ala, uncleaved

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005764	cellular_component	lysosome
A	0006631	biological_process	fatty acid metabolic process
A	0006665	biological_process	sphingolipid metabolic process
A	0016787	molecular_function	hydrolase activity
A	0017040	molecular_function	N-acylsphingosine amidohydrolase activity
A	0017064	molecular_function	fatty acid amide hydrolase activity
B	0005576	cellular_component	extracellular region
B	0005764	cellular_component	lysosome
B	0006631	biological_process	fatty acid metabolic process
B	0006665	biological_process	sphingolipid metabolic process
B	0016787	molecular_function	hydrolase activity
B	0017040	molecular_function	N-acylsphingosine amidohydrolase activity
B	0017064	molecular_function	fatty acid amide hydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000269|PubMed:29692406

Chain	Residue	Details
A	ALA143
B	ALA143

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site_id	SWS_FT_FI2
Number of Residues	6
Details	SITE: Important for catalytic activity => ECO:0000250|UniProtKB:Q13510

Chain	Residue	Details
A	ASP162
A	ASN320
A	ARG333
B	ASP162
B	ASN320
B	ARG333

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site_id	SWS_FT_FI3
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:29692406, ECO:0007744|PDB:5U84

Chain	Residue	Details
A	ASN173
A	ASN259
B	ASN173
B	ASN259

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site_id	SWS_FT_FI4
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN342
A	ASN348
B	ASN342
B	ASN348

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