5VEM
Human ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5)
Summary for 5VEM
| Entry DOI | 10.2210/pdb5vem/pdb |
| Related | 5VEN 5VEO |
| Descriptor | Ectonucleotide pyrophosphatase/phosphodiesterase family member 5, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
| Functional Keywords | hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 148997.91 |
| Authors | Gorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B. (deposition date: 2017-04-05, release date: 2017-09-20, Last modification date: 2020-07-29) |
| Primary citation | Gorelik, A.,Randriamihaja, A.,Illes, K.,Nagar, B. A key tyrosine substitution restricts nucleotide hydrolysis by the ectoenzyme NPP5. FEBS J., 284:3718-3726, 2017 Cited by PubMed: 28898552DOI: 10.1111/febs.14266 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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