5VEM
Human ectonucleotide pyrophosphatase / phosphodiesterase 5 (ENPP5, NPP5)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000210 | molecular_function | NAD+ diphosphatase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007154 | biological_process | cell communication |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000210 | molecular_function | NAD+ diphosphatase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007154 | biological_process | cell communication |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000210 | molecular_function | NAD+ diphosphatase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0007154 | biological_process | cell communication |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016020 | cellular_component | membrane |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:28898552, ECO:0007744|PDB:5VEM |
| Chain | Residue | Details |
| A | THR72 | |
| B | THR72 | |
| C | THR72 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28898552, ECO:0007744|PDB:5VEM |
| Chain | Residue | Details |
| A | ASP36 | |
| B | ASP191 | |
| B | HIS195 | |
| B | ASP238 | |
| B | HIS239 | |
| B | HIS339 | |
| C | ASP36 | |
| C | THR72 | |
| C | ASP191 | |
| C | HIS195 | |
| C | ASP238 | |
| A | THR72 | |
| C | HIS239 | |
| C | HIS339 | |
| A | ASP191 | |
| A | HIS195 | |
| A | ASP238 | |
| A | HIS239 | |
| A | HIS339 | |
| B | ASP36 | |
| B | THR72 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN101 | |
| B | ASN158 | |
| B | ASN292 | |
| B | ASN329 | |
| B | ASN362 | |
| B | ASN369 | |
| B | ASN382 | |
| B | ASN389 | |
| C | ASN101 | |
| C | ASN158 | |
| C | ASN292 | |
| A | ASN158 | |
| C | ASN329 | |
| C | ASN362 | |
| C | ASN369 | |
| C | ASN382 | |
| C | ASN389 | |
| A | ASN292 | |
| A | ASN329 | |
| A | ASN362 | |
| A | ASN369 | |
| A | ASN382 | |
| A | ASN389 | |
| B | ASN101 |
