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STRUCTURE OF THE ANTI-HIV ANTIBODY DH501 THAT BINDS GP120 V3 GLYCAN AND THE BASE OF V3 WITH FREE MAN9 GLYCAN
分子名称:	CALCIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose, antibody DH501 Fab heavy chain, ...
著者	Nicely, N.I, Haynes, B.F.
登録日	2016-08-30
公開日	2017-03-08
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.991 Å)
主引用文献	Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates. Cell Rep, 18, 2017

5U0U

Crystal Structure of DH270.1 (unliganded, single-chain Fv) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
分子名称:	DH270.1 single-chain variable fragment
著者	Fera, D, Harrison, S.C.
登録日	2016-11-27
公開日	2017-03-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3.428 Å)
主引用文献	Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017

5U3J

Crystal Structure of DH511.1 Fab in Complex with HIV-1 gp41 MPER Peptide
分子名称:	DH511.1 Heavy Chain, DH511.1 Light Chain, gp41 MPER peptide
著者	Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
登録日	2016-12-02
公開日	2017-02-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.74 Å)
主引用文献	Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

5U3P

Crystal Structure of DH511.4 Fab
分子名称:	DH511.4 Fab Heavy Chain, DH511.4 Fab Light Chain
著者	Nicely, N.I, Williams, L.D, Ofek, G, Haynes, B.F.
登録日	2016-12-02
公開日	2017-02-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

5U15

Crystal Structure of DH270.UCA3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
分子名称:	DH270.UCA3 heavy chain, DH270.UCA3 light chain
著者	Fera, D, Harrison, S.C.
登録日	2016-11-27
公開日	2017-03-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.26 Å)
主引用文献	Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017

5TQA

Crystal Structure of DH270.6 (unliganded) from the DH270 Broadly Neutralizing N332-Glycan Dependent Lineage
分子名称:	DH270.6 Fab heavy chain, DH270.6 Fab light chain
著者	Fera, D, Harrison, S.C.
登録日	2016-10-23
公開日	2017-03-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.723 Å)
主引用文献	Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017

5U3L

Crystal Structure of DH511.2 Fab in Complex with HIV-1 gp41 MPER 670-683 Peptide
分子名称:	DH511.2 Fab Heavy Chain, DH511.2 Fab Light Chain, gp41 MPER peptide
著者	Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
登録日	2016-12-02
公開日	2017-02-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.165 Å)
主引用文献	Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

5TRP

Crystal Structure of the Unliganded DH270 Cooperating Lineage Member DH272
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DH272 Fab heavy chain, DH272 Fab light chain, ...
著者	Fera, D, Harrison, S.C.
登録日	2016-10-27
公開日	2017-03-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.692 Å)
主引用文献	Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017

5TPP

Crystal Structure of DH270.5 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
分子名称:	CITRIC ACID, DH270.5 Fab heavy chain, DH270.5 Fab light chain, ...
著者	Fera, D, Harrison, S.C.
登録日	2016-10-20
公開日	2017-03-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017

5U3K

Crystal Structure of DH511.2 Fab in Complex with HIV-1 gp41 MPER 662-683 Peptide
分子名称:	CALCIUM ION, CHLORIDE ION, DH511.2 Fab Heavy Chain, ...
著者	Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
登録日	2016-12-02
公開日	2017-02-15
最終更新日	2019-12-11
実験手法	X-RAY DIFFRACTION (2.637 Å)
主引用文献	Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

5U3O

Crystal Structure of DH511.2_K3 Fab in Complex with HIV-1 gp41 MPER Peptide
分子名称:	DH511.2_K3 Fab Heavy Chain, DH511.2_K3 Fab Light Chain, gp41 MPER peptide
著者	Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
登録日	2016-12-02
公開日	2017-02-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.761 Å)
主引用文献	Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

5U0R

Crystal Structure of DH270.UCA1 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
分子名称:	DH270.UCA1 heavy chain, DH270.UCA1 light chain, SULFATE ION
著者	Fera, D, Harrison, S.C.
登録日	2016-11-26
公開日	2017-03-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (3.295 Å)
主引用文献	Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017

5U3N

Crystal Structure of DH511.12P Fab in Complex with HIV-1 gp41 MPER Peptide
分子名称:	DH511.12P Fab Heavy Chain, DH511.12P Fab Light Chain, gp41 MPER peptide
著者	Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
登録日	2016-12-02
公開日	2017-02-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

5TPL

Crystal Structure of DH270.3 (unliganded) from the DH270 Broadly Neutralizing N332-glycan Dependent Lineage
分子名称:	DH270.3 Fab heavy chain, DH270.3 Fab light chain
著者	Fera, D, Harrison, S.C.
登録日	2016-10-20
公開日	2017-03-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med, 9, 2017

5U3M

Crystal Structure of DH511.11P Fab in Complex with HIV-1 gp41 MPER Peptide
分子名称:	DH511.11P Fab Heavy Chain, DH511.11P Fab Light Chain, gp41 MPER peptide
著者	Ofek, G, Wu, L, Lougheed, C.S, Williams, L.D, Nicely, N.I, Haynes, B.F.
登録日	2016-12-02
公開日	2017-02-15
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.418 Å)
主引用文献	Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Sci Immunol, 2, 2017

5UKN

Structure of unliganded anti-gp120 CD4bs antibody DH522UCA Fab
分子名称:	CHLORIDE ION, DH522UCA Fab fragment heavy chain, DH522UCA Fab fragment light chain
著者	Nicely, N.I.
登録日	2017-01-23
公開日	2017-12-06
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017

5UKP

Structure of unliganded anti-gp120 CD4bs antibody DH522.1 Fab
分子名称:	DH522.1 Fab fragment heavy chain, DH522.1 Fab fragment light chain
著者	Nicely, N.I.
登録日	2017-01-23
公開日	2017-12-06
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017

5UKR

Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab in complex with a gp120 core
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Chimeric B.YU2 gp120 core derived from HIV-1 Env, DH522.2 Fab fragment heavy chain, ...
著者	Nicely, N.I.
登録日	2017-01-23
公開日	2017-12-06
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.712 Å)
主引用文献	Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017

5UIX

Crystal Structure of the DH576 CD4bs Fab (unliganded) from the RV305 HIV Vaccine Trial
分子名称:	DH576 Fab heavy chain, DH576 Fab light chain
著者	Fera, D, Harrison, S.C.
登録日	2017-01-15
公開日	2017-03-08
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.501 Å)
主引用文献	Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial. PLoS Pathog., 13, 2017

5UKO

Structure of unliganded anti-gp120 CD4bs antibody DH522IA Fab
分子名称:	DH522IA Fab fragment heavy chain, DH522IA Fab fragment light chain
著者	Nicely, N.I.
登録日	2017-01-23
公開日	2017-12-06
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017

5UKQ

Structure of unliganded anti-gp120 CD4bs antibody DH522.2 Fab
分子名称:	DH522.2 Fab fragment heavy chain, DH522.2 Fab fragment light chain, GLYCEROL
著者	Nicely, N.I.
登録日	2017-01-23
公開日	2017-12-06
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nat Commun, 8, 2017

7U04

IOMA class antibody ACS101
分子名称:	GLYCEROL, IOMA class antibody ACS101 heavy chain, IOMA class antibody ACS101 light chain
著者	Farokhi, E, Stanfield, R.L, Wilson, I.A.
登録日	2022-02-17
公開日	2022-08-24
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.31 Å)
主引用文献	Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nat Commun, 13, 2022

7TLC

Down-state locked, S2 stabilized rS2d-HexaPro SARS-CoV-2 spike ectodomain in the RBD-down conformation, State 1
分子名称:	Spike glycoprotein
著者	Henderson, R, Acharya, P.
登録日	2022-01-18
公開日	2022-02-02
最終更新日	2023-04-12
実験手法	ELECTRON MICROSCOPY (2.83 Å)
主引用文献	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

7TLA

Down-state locked rS2d SARS-CoV-2 spike ectodomain in the RBD-down conformation, State 1
分子名称:	Spike glycoprotein
著者	Henderson, R, Acharya, P.
登録日	2022-01-18
公開日	2022-02-02
最終更新日	2023-04-12
実験手法	ELECTRON MICROSCOPY (3.13 Å)
主引用文献	Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82, 2022

7U0K

IOMA class antibody Fab ACS124
分子名称:	2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, IOMA Class antibody ACS124 Heavy chain, IOMA Class antibody ACS124 Light chain
著者	Farokhi, E, Stanfield, R.L, Wilson, I.A.
登録日	2022-02-18
公開日	2022-08-24
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (1.73 Å)
主引用文献	Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein. Nat Commun, 13, 2022

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