5U3O

Crystal Structure of DH511.2_K3 Fab in Complex with HIV-1 gp41 MPER Peptide

Summary for 5U3O

• Entry DOI: 10.2210/pdb5u3o/pdb
• Related: 5U3J 5U3K 5U3L 5U3M 5U3N 5U3P
• Descriptor: DH511.2_K3 Fab Heavy Chain, DH511.2_K3 Fab Light Chain, gp41 MPER peptide, ... (4 entities in total)
• Functional Keywords: hiv-1, neutralizing, antibody, gp41, mper, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 52153.68

Authors

Ofek, G.,Wu, L.,Lougheed, C.S.,Williams, L.D.,Nicely, N.I.,Haynes, B.F. (deposition date: 2016-12-02, release date: 2017-02-15, Last modification date: 2023-10-04)

• Primary citation: Williams, L.D.,Ofek, G.,Schatzle, S.,McDaniel, J.R.,Lu, X.,Nicely, N.I.,Wu, L.,Lougheed, C.S.,Bradley, T.,Louder, M.K.,McKee, K.,Bailer, R.T.,O'Dell, S.,Georgiev, I.S.,Seaman, M.S.,Parks, R.J.,Marshall, D.J.,Anasti, K.,Yang, G.,Nie, X.,Tumba, N.L.,Wiehe, K.,Wagh, K.,Korber, B.,Kepler, T.B.,Munir Alam, S.,Morris, L.,Kamanga, G.,Cohen, M.S.,Bonsignori, M.,Xia, S.M.,Montefiori, D.C.,Kelsoe, G.,Gao, F.,Mascola, J.R.,Moody, M.A.,Saunders, K.O.,Liao, H.X.,Tomaras, G.D.,Georgiou, G.,Haynes, B.F.; Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.; Sci Immunol, 2:-, 2017; PubMed: 28783671; DOI: 10.1126/sciimmunol.aal2200

Experimental method

X-RAY DIFFRACTION (1.761 Å)