7U0K

IOMA class antibody Fab ACS124

Summary for 7U0K

• Entry DOI: 10.2210/pdb7u0k/pdb
• Descriptor: IOMA Class antibody ACS124 Light chain, IOMA Class antibody ACS124 Heavy chain, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (4 entities in total)
• Functional Keywords: hiv, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47964.71

Authors

Farokhi, E.,Stanfield, R.L.,Wilson, I.A. (deposition date: 2022-02-18, release date: 2022-08-24, Last modification date: 2023-10-18)

• Primary citation: van Schooten, J.,Farokhi, E.,Schorcht, A.,van den Kerkhof, T.L.G.M.,Gao, H.,van der Woude, P.,Burger, J.A.,Meesters, T.G.R.,Bijl, T.,Ghalaiyini, R.,Turner, H.L.,Dorning, J.,van Schaik, B.D.C.,van Kampen, A.H.C.,Labranche, C.C.,Stanfield, R.L.,Sok, D.,Montefiori, D.C.,Burton, D.R.,Seaman, M.S.,Ozorowski, G.,Wilson, I.A.,Sanders, R.W.,Ward, A.B.,van Gils, M.J.; Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein.; Nat Commun, 13:4515-4515, 2022; PubMed: 35922441; DOI: 10.1038/s41467-022-32208-0

Experimental method

X-RAY DIFFRACTION (1.73 Å)