2YGO
 
 | | WIF domain-EGF-like domain 1 of human Wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | | 著者 | Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y. | | 登録日 | 2011-04-19 | | 公開日 | 2011-07-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1
Nat.Struct.Mol.Biol., 18, 2011
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2YGN
 | | WIF domain of human Wnt inhibitory factor 1 in complex with 1,2- dipalmitoylphosphatidylcholine | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | | 著者 | Malinauskas, T, Aricescu, A.R, Lu, W, Siebold, C, Jones, E.Y. | | 登録日 | 2011-04-19 | | 公開日 | 2011-07-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Modular Mechanism of Wnt Signaling Inhibition by Wnt Inhibitory Factor 1
Nat.Struct.Mol.Biol., 18, 2011
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1F3M
 | | CRYSTAL STRUCTURE OF HUMAN SERINE/THREONINE KINASE PAK1 | | 分子名称: | IODIDE ION, SERINE/THREONINE-PROTEIN KINASE PAK-ALPHA | | 著者 | Lei, M, Lu, W, Meng, W, Parrini, M.-C, Eck, M.J, Mayer, B.J, Harrison, S.C. | | 登録日 | 2000-06-05 | | 公開日 | 2000-06-29 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch.
Cell(Cambridge,Mass.), 102, 2000
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1CT4
 | | CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-VAL18I IN COMPLEX WITH SGPB | | 分子名称: | OVOMUCOID INHIBITOR, PROTEINASE B | | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 1999-08-18 | | 公開日 | 2000-01-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB.
Protein Sci., 9, 2000
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1CSO
 | | CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-ILE18I IN COMPLEX WITH SGPB | | 分子名称: | OVOMUCOID INHIBITOR, PROTEINASE B | | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 1999-08-18 | | 公開日 | 2000-01-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB.
Protein Sci., 9, 2000
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1CT0
 | | CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-SER18I IN COMPLEX WITH SGPB | | 分子名称: | OVOMUCOID INHIBITOR, PROTEINASE B | | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 1999-08-18 | | 公開日 | 2000-01-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB.
Protein Sci., 9, 2000
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1CT2
 | | CRYSTAL STRUCTURE OF THE OMTKY3 P1 VARIANT OMTKY3-THR18I IN COMPLEX WITH SGPB | | 分子名称: | OVOMUCOID INHIBITOR, PROTEINASE B | | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N. | | 登録日 | 1999-08-18 | | 公開日 | 2000-01-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Deleterious effects of beta-branched residues in the S1 specificity pocket of Streptomyces griseus proteinase B (SGPB): crystal structures of the turkey ovomucoid third domain variants Ile18I, Val18I, Thr18I, and Ser18I in complex with SGPB.
Protein Sci., 9, 2000
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1DS3
 | | CRYSTAL STRUCTURE OF OMTKY3-CH2-ASP19I | | 分子名称: | OVOMUCOID | | 著者 | Bateman, K.S, Huang, K, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 2000-01-06 | | 公開日 | 2001-01-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
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1DS2
 | | CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I | | 分子名称: | OVOMUCOID, PROTEINASE B (SGPB) | | 著者 | Bateman, K.S, Huang, K, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | | 登録日 | 2000-01-06 | | 公開日 | 2001-01-31 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I
J.Mol.Biol., 305, 2001
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2PM1
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2PM5
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2PLZ
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2PM4
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1ZMK
 | | Crystal structure of human alpha-defensin-2 (variant Gly16-> D-ALA), P 42 21 2 space group | | 分子名称: | CHLORIDE ION, GLYCEROL, Neutrophil defensin 2 | | 著者 | Lubkowski, J, Prahl, A, Lu, W. | | 登録日 | 2005-05-10 | | 公開日 | 2005-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
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1ZMI
 | | Crystal structure of human alpha_defensin-2 (variant GLY16->D-ALA), P 32 2 1 space group ) | | 分子名称: | GLYCEROL, Neutrophil defensin 2, SULFATE ION | | 著者 | Lubkowski, J, Prahl, A, Lu, W. | | 登録日 | 2005-05-10 | | 公開日 | 2005-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
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1ONJ
 | | Crystal structure of Atratoxin-b from Chinese cobra venom of Naja atra | | 分子名称: | Cobrotoxin b, SULFATE ION | | 著者 | Lou, X, Tu, X, Pan, G, Xu, C, Fan, R, Lu, W, Deng, W, Rao, P, Teng, M, Niu, L. | | 登録日 | 2003-02-28 | | 公開日 | 2004-02-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.555 Å) | | 主引用文献 | Purification, N-terminal sequencing, crystallization and preliminary structural determination of atratoxin-b, a short-chain alpha-neurotoxin from Naja atra venom.
Acta Crystallogr.,Sect.D, 59, 2003
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5DOX
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Hygromycin-A at 3.1A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N. | | 登録日 | 2015-09-11 | | 公開日 | 2015-12-30 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
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1ZMH
 | | Crystal structure of human neutrophil peptide 2, HNP-2 (variant Gly16-> D-Ala) | | 分子名称: | GLYCEROL, HEXAETHYLENE GLYCOL, Neutrophil defensin 2, ... | | 著者 | Lubkowski, J, Prahl, A, Lu, W. | | 登録日 | 2005-05-10 | | 公開日 | 2005-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.
J.Biol.Chem., 280, 2005
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1NR2
 | | High resolution crystal structures of thymus and activation-regulated chemokine | | 分子名称: | Thymus and activation-regulated chemokine | | 著者 | Asojo, O.A, Boulegue, C, Hoover, D.M, Lu, W, Lubkowski, J. | | 登録日 | 2003-01-23 | | 公開日 | 2003-08-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structures of thymus and activation-regulated chemokine (TARC).
Acta Crystallogr.,Sect.D, 59, 2003
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1NR4
 | | High resolution crystal structures of thymus and activation-regulated chemokine | | 分子名称: | SULFATE ION, Thymus and activation-regulated chemokine | | 著者 | Asojo, O.A, Boulegue, C, Hoover, D.M, Lu, W, Lubkowski, J. | | 登録日 | 2003-01-23 | | 公開日 | 2003-08-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Structures of thymus and activation-regulated chemokine (TARC).
Acta Crystallogr.,Sect.D, 59, 2003
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3LNJ
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5SVR
 | | Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-{[(3-phenoxyphenyl)methyl][(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}benzene-1,2,4-tricarboxylic acid, MAGNESIUM ION, ... | | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | | 登録日 | 2016-08-07 | | 公開日 | 2016-10-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
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5SVK
 | | Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, open state | | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | | 登録日 | 2016-08-06 | | 公開日 | 2016-09-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
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5SVT
 | | Anomalous Cs+ signal reveals the site of Na+ ion entry to the channel pore of the human P2X3 ion channel through the extracellular fenestrations | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, P2X purinoceptor 3, ... | | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | | 登録日 | 2016-08-07 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.794 Å) | | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
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5SVP
 | | Anomalous sulfur signal reveals the position of agonist 2-methylthio-ATP bound to the ATP-gated human P2X3 ion channel in the desensitized state | | 分子名称: | 1,2-ETHANEDIOL, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Mansoor, S.E, Lu, W, Oosterheert, W, Shekhar, M, Tajkhorshid, E, Gouaux, E. | | 登録日 | 2016-08-07 | | 公開日 | 2016-09-28 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.298 Å) | | 主引用文献 | X-ray structures define human P2X3 receptor gating cycle and antagonist action.
Nature, 538, 2016
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