1ZMI
Crystal structure of human alpha_defensin-2 (variant GLY16->D-ALA), P 32 2 1 space group )
Summary for 1ZMI
Entry DOI | 10.2210/pdb1zmi/pdb |
Related | 1DFN 1ZMH 1ZMK 1ZMM 1ZMP 1ZMQ |
Descriptor | Neutrophil defensin 2, GLYCEROL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | alpha-defensin, antimicrobial, d-amino acid substitution, antimicrobial protein |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P59666 |
Total number of polymer chains | 4 |
Total formula weight | 14236.80 |
Authors | Lubkowski, J.,Prahl, A.,Lu, W. (deposition date: 2005-05-10, release date: 2005-08-16, Last modification date: 2023-08-23) |
Primary citation | Xie, C.,Prahl, A.,Ericksen, B.,Wu, Z.,Zeng, P.,Li, X.,Lu, W.Y.,Lubkowski, J.,Lu, W. Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids. J.Biol.Chem., 280:32921-32929, 2005 Cited by PubMed: 15894545DOI: 10.1074/jbc.M503084200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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