2PLZ

Arg-modified human beta-defensin 1 (HBD1)

Summary for 2PLZ

Entry DOI	10.2210/pdb2plz/pdb
Related	2IJU 2IJV
Descriptor	Beta-defensin 1, SULFATE ION (3 entities in total)
Functional Keywords	antimicrobial, chemotactic, defensin, antimicrobial protein
Biological source	Homo sapiens (human)
Cellular location	Secreted: P60022
Total number of polymer chains	1
Total formula weight	4436.91
Authors	Lubkowski, J.,Pazgier, M.,Lu, W. (deposition date: 2007-04-20, release date: 2007-05-29, Last modification date: 2024-04-03)
Primary citation	Zou, G.,de Leeuw, E.,Li, C.,Pazgier, M.,Li, C.,Zeng, P.,Lu, W.Y.,Lubkowski, J.,Lu, W. Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs. J.Biol.Chem., 282:19653-19665, 2007 Cited by PubMed: 17452329 DOI: 10.1074/jbc.M611003200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.36 Å)

Structure validation