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6W6K
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30S-Activated-high-Mg2+
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Jahagirdar, D, Jha, V, Basu, B, Gomez-Blanco, J, Vargas, J, Ortega, J.
登録日2020-03-17
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy.
Rna, 26, 2020
2L38
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R29Q Sticholysin II mutant
分子名称: Sticholysin-2
著者Castrillo, I, Alegre-Cebollada, J, Martinez-del-Pozo, A, Gavilanes, J, Bruix, M.
登録日2010-09-10
公開日2010-09-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Structure of StnIIR29Q, a defective lipid binding mutant of the sea anemone actinoporin Sticholysin II
To be Published
2F77
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Solution structure of the R55F mutant of M-PMV matrix protein (p10)
分子名称: Core protein p10
著者Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R.
登録日2005-11-30
公開日2006-12-05
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein.
Proc.Natl.Acad.Sci.USA, 105, 2008
2LJR
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GLUTATHIONE TRANSFERASE APO-FORM FROM HUMAN
分子名称: GLUTATHIONE S-TRANSFERASE
著者Rossjohn, J, Mckinstry, W.J, Oakley, A.J, Verger, D, Flanagan, J, Chelvanayagam, G, Tan, K.L, Board, P.G, Parker, M.W.
登録日1998-03-08
公開日1999-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site.
Structure, 6, 1998
2F76
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BU of 2f76 by Molmil
Solution structure of the M-PMV wild type matrix protein (p10)
分子名称: Core protein p10
著者Vlach, J, Lipov, J, Veverka, V, Lang, J, Srb, P, Rumlova, M, Hunter, E, Ruml, T, Hrabal, R.
登録日2005-11-30
公開日2006-12-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein.
Proc.Natl.Acad.Sci.USA, 105, 2008
2K7P
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Filamin A Ig-like domains 16-17
分子名称: Filamin-A
著者Heikkinen, O.K, Kilpelainen, I, Koskela, H, Permi, P, Heikkinen, S, Ylanne, J.
登録日2008-08-19
公開日2009-07-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin
J.Biol.Chem., 284, 2009
2K7Q
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Filamin A Ig-like domains 18-19
分子名称: Filamin-A
著者Heikkinen, O.K, Kilpelainen, I, Koskela, H, Permi, P, Heikkinen, S, Ylanne, J.
登録日2008-08-19
公開日2009-07-07
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin
J.Biol.Chem., 284, 2009
2J3S
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BU of 2j3s by Molmil
Crystal structure of the human filamin A Ig domains 19 to 21
分子名称: 1,4-DIETHYLENE DIOXIDE, BROMIDE ION, FILAMIN-A, ...
著者Kiema, T.-R, Ylanne, J.
登録日2006-08-23
公開日2007-10-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Three Tandem Filamin Domains Reveals Auto-Inhibition of Ligand-Binding.
Embo J., 26, 2007
6QI5
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BU of 6qi5 by Molmil
Near Atomic Structure of an Atadenovirus Shows a possible gene duplication event and Intergenera Variations in Cementing Proteins
分子名称: Hexon protein, PIIIa, Penton protein, ...
著者Condezo, G.N, Marabini, R, Gomez-Blanco, J, SanMartin, C.
登録日2019-01-17
公開日2020-08-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Near-atomic structure of an atadenovirus reveals a conserved capsid-binding motif and intergenera variations in cementing proteins.
Sci Adv, 7, 2021
4J29
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Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR258.
分子名称: Engineered Protein OR258
著者Vorobiev, S, Su, M, Koga, R, Seetharaman, J, Koga, N, Mao, L, Xiao, R, Kohan, E, Castelllanos, J, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2013-02-04
公開日2013-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Engineered Protein OR258.
To be Published
6ZYY
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BU of 6zyy by Molmil
Outer Dynein Arm-Shulin complex - Dyh3 motor region (Tetrahymena thermophila)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Mali, G.R, Abid Ali, F, Lau, C.K, Begum, F, Boulanger, J, Howe, J.D, Chen, Z.A, Rappsilber, J, Skehel, M, Carter, A.P.
登録日2020-08-03
公開日2021-02-03
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Shulin packages axonemal outer dynein arms for ciliary targeting.
Science, 371, 2021
8C89
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BU of 8c89 by Molmil
SARS-CoV-2 spike in complex with the 17T2 neutralizing antibody Fab fragment (local refinement of RBD and Fab)
分子名称: 17T2 Fab heavy chain, 17T2 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Modrego, A, Carlero, D, Bueno-Carrasco, M.T, Santiago, C, Carolis, C, Arranz, R, Blanco, J, Magri, G.
登録日2023-01-19
公開日2024-01-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.41 Å)
主引用文献A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity.
Nat Commun, 15, 2024
4MGX
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BU of 4mgx by Molmil
Crystal structure of human filamin C domains 4-5 and GPIB alpha cytoplasmic domain complex
分子名称: Filamin-C, Platelet glycoprotein Ib alpha chain
著者Sethi, R, Ylanne, J.
登録日2013-08-29
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献A Novel Structural Unit in the N-terminal Region of Filamins.
J.Biol.Chem., 289, 2014
4M9P
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Crystal structure of the human filamin A Ig-like domains 3-5
分子名称: Filamin-A
著者Seppala, J, Pentikainen, U, Ylanne, J.
登録日2013-08-15
公開日2014-02-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献A Novel Structural Unit in the N-terminal Region of Filamins.
J.Biol.Chem., 289, 2014
7UCX
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BU of 7ucx by Molmil
LRP8 11H1 Fab complexed to a cyclized CR1 peptide
分子名称: 11H1 Fab Heavy chain, 11H1 Fab Light chain, Cyclized CR1 peptide, ...
著者Argiriadi, M.A, Deng, K, Egan, D, Gao, L, Gizatullin, F, Harlan, J, Karaoglu, D, Qiu, W, Goodearl, A.
登録日2022-03-17
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献The use of cyclic peptide antigens to generate LRP8 specific antibodies
Front Drug Discov (Lausanne), 2, 2023
2JF1
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BU of 2jf1 by Molmil
CRYSTAL STRUCTURE OF THE FILAMIN A REPEAT 21 COMPLEXED WITH THE INTEGRIN BETA2 CYTOPLASMIC TAIL PEPTIDE
分子名称: FILAMIN-A, GLYCEROL, INTEGRIN BETA-2 SUBUNIT
著者Kiema, T, Ylanne, J.
登録日2007-01-25
公開日2008-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.
Blood, 112, 2008
2K3W
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BU of 2k3w by Molmil
NMR structure of VPS4A-MIT-CHMP6
分子名称: Charged multivesicular body protein 6, Vacuolar protein sorting-associating protein 4A
著者Kieffer, C, Skalicky, J.J, Morita, E, De Domini, I, Ward, D.M, Kaplan, J, Sundquist, W.I.
登録日2008-05-19
公開日2008-10-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding
Dev.Cell, 15, 2008
2K3T
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BU of 2k3t by Molmil
Solution Structure of IG-Like Domain 23 from Human Filamin A
分子名称: Filamin-A
著者Heikkinen, O.K, Ylanne, J, Kilpelainen, I, Kupiainen, O.
登録日2008-05-16
公開日2009-03-31
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Molecular basis of filamin A-FilGAP interaction and its impairment in congenital disorders associated with filamin A mutations
Plos One, 4, 2009
2NQC
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BU of 2nqc by Molmil
Crystal structure of ig-like domain 23 from human filamin C
分子名称: Filamin-C, GLYCEROL, IMIDAZOLE, ...
著者Sjekloca, L, Pudas, R, Sjoeblom, B, Konarev, P, Carugo, O, Rybin, V, Kiema, T.R, Svergun, D, Ylanne, J, Djinovic-Carugo, K.
登録日2006-10-31
公開日2007-09-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of human filamin C domain 23 and small angle scattering model for filamin C 23-24 dimer
J.Mol.Biol., 368, 2007
2KDG
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Solution Structure of the 1st Ig domain of Myotilin
分子名称: Myotilin
著者Heikkinen, O, Kilpelainen, I, Permi, P, Koskela, H, Ylanne, J, Carpen, O.
登録日2009-01-08
公開日2009-07-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the first immunoglobulin domain of human myotilin
J.Biomol.Nmr, 44, 2009
3LJR
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BU of 3ljr by Molmil
GLUTATHIONE TRANSFERASE (THETA CLASS) FROM HUMAN IN COMPLEX WITH THE GLUTATHIONE CONJUGATE OF 1-MENAPHTHYL SULFATE
分子名称: 1-MENAPHTHYL GLUTATHIONE CONJUGATE, GLUTATHIONE S-TRANSFERASE, SULFATE ION
著者Rossjohn, J, Mckinstry, W.J, Oakley, A.J, Verger, D, Flanagan, J, Chelvanayagam, G, Tan, K.L, Board, P.G, Parker, M.W.
登録日1998-03-08
公開日1999-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Human theta class glutathione transferase: the crystal structure reveals a sulfate-binding pocket within a buried active site.
Structure, 6, 1998
3J3I
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BU of 3j3i by Molmil
Penicillium chrysogenum virus (PcV) capsid structure
分子名称: Capsid protein
著者Luque, D, Gomez-Blanco, J, Garriga, D, Brilot, A, Gonzalez, J.M, Havens, W.H, Carrascosa, J.L, Trus, B.L, Verdaguer, N, Grigorieff, N, Ghabrial, S.A, Caston, J.R.
登録日2013-03-08
公開日2014-05-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM near-atomic structure of a dsRNA fungal virus shows ancient structural motifs preserved in the dsRNA viral lineage.
Proc.Natl.Acad.Sci.USA, 111, 2014
1NHZ
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Crystal Structure of the Antagonist Form of Glucocorticoid Receptor
分子名称: 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, GLUCOCORTICOID RECEPTOR, HEXANE-1,6-DIOL
著者Kauppi, B, Jakob, C, Farnegardh, M, Yang, J, Ahola, H, Alarcon, M, Calles, K, Engstrom, O, Harlan, J, Muchmore, S, Ramqvist, A.-K, Thorell, S, Ohman, L, Greer, J, Gustafsson, J.-A, Carlstedt-Duke, J, Carlquist, M.
登録日2002-12-20
公開日2003-05-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain: RU-486 INDUCES A TRANSCONFORMATION THAT LEADS TO ACTIVE ANTAGONISM.
J.Biol.Chem., 278, 2003
2XNB
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Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents
分子名称: 3,4-DIMETHYL-5-(2-{[(1Z)-4-PIPERAZIN-1-YLCYCLOHEXA-2,4-DIEN-1-YLIDENE]AMINO}PYRIMIDIN-4-YL)-1,3-THIAZOL-2(3H)-ONE, CELL DIVISION PROTEIN KINASE 2
著者Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M.
登録日2010-08-01
公開日2010-11-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010
2XMY
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Discovery and Characterisation of 2-Anilino-4-(thiazol-5-yl) pyrimidine Transcriptional CDK Inhibitors as Anticancer Agents
分子名称: 4-[4-(3,4-DIMETHYL-2-OXO-2,3-DIHYDRO-THIAZOL-5-YL)-PYRIMIDIN-2-YLAMINO]-N-(2-METHOXY-ETHYL)-BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2
著者Wang, S, Griffiths, G, Midgley, C.A, Barnett, A.L, Cooper, M, Grabarek, J, Ingram, L, Jackson, W, Kontopidis, G, McClue, S.J, McInnes, C, McLachlan, J, Meades, C, Mezna, M, Stuart, I, Thomas, M.P, Zheleva, D.I, Lane, D.P, Jackson, R.C, Glover, D.M, Blake, D.G, Fischer, P.M.
登録日2010-07-29
公開日2010-11-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery and Characterisation of 2-Anilino-4-(Thiazol-5-Yl)Pyrimidine Transcriptional Cdk Inhibitors as Anticancer Agents
Chem.Biol., 17, 2010

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