2K3W

NMR structure of VPS4A-MIT-CHMP6

Summary for 2K3W

Entry DOI	10.2210/pdb2k3w/pdb
Descriptor	Vacuolar protein sorting-associating protein 4A, Charged multivesicular body protein 6 (2 entities in total)
Functional Keywords	esrct-iii, chmp6, mit, atp-binding, membrane, nucleotide-binding, protein transport, transport, coiled coil, endosome, lipoprotein, myristate
Biological source	Homo sapiens (human) More
Cellular location	Prevacuolar compartment membrane; Peripheral membrane protein: Q9UN37 Endomembrane system: Q96FZ7
Total number of polymer chains	2
Total formula weight	11700.34
Authors	Kieffer, C.,Skalicky, J.J.,Morita, E.,De Domini, I.,Ward, D.M.,Kaplan, J.,Sundquist, W.I. (deposition date: 2008-05-19, release date: 2008-10-28, Last modification date: 2024-05-29)
Primary citation	Kieffer, C.,Skalicky, J.J.,Morita, E.,De Domenico, I.,Ward, D.M.,Kaplan, J.,Sundquist, W.I. Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding Dev.Cell, 15:62-73, 2008 Cited by PubMed: 18606141 DOI: 10.1016/j.devcel.2008.05.014 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation