2JP7
 
 | | NMR structure of the Mex67 UBA domain | | 分子名称: | mRNA export factor MEX67 | | 著者 | Hobeika, M, Brockmann, C, Iglesias, N, Gwizdek, C, Neuhaus, D, Stutz, F, Stewart, M, Divita, G, Dargemont, C. | | 登録日 | 2007-04-26 | | 公開日 | 2007-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Coordination of Hpr1 and ubiquitin binding by the UBA domain of the mRNA export factor Mex67
Mol.Cell.Biol., 18, 2007
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2JPS
 | | NAB2 N-terminal domain | | 分子名称: | Nuclear polyadenylated RNA-binding protein NAB2 | | 著者 | Grant, R, Marshall, N.J, Yang, J, Fasken, M, Kelly, S, Harreman, M.T, Neuhaus, D, Corbett, A.H, Stewart, M. | | 登録日 | 2007-05-23 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the N-terminal Mlp1-binding domain of the Saccharomyces cerevisiae mRNA-binding protein, Nab2
J.Mol.Biol., 376, 2008
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2KHH
 | | Structural requirements for the UBA domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation Tho complex component Hpr1 and nucleoporin FxFG repeats | | 分子名称: | FxFG, mRNA export factor MEX67 | | 著者 | Hobeika, M, Brockmann, C, Gruessing, F, Neuhaus, D, Divita, G, Stewart, M, Dargemont, C. | | 登録日 | 2009-04-06 | | 公開日 | 2009-05-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural requirements for the ubiquitin-associated domain of the mRNA export factor Mex67 to bind its specific targets, the transcription elongation THO complex component Hpr1 and nucleoporin FXFG repeats
J.Biol.Chem., 284, 2009
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2K0A
 | | 1H, 15N and 13C chemical shift assignments for Rds3 protein | | 分子名称: | Pre-mRNA-splicing factor RDS3, ZINC ION | | 著者 | Loening, N, van Roon, A, Yang, J, Nagai, K, Neuhaus, D. | | 登録日 | 2008-01-31 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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6RH6
 | | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of NECAP1 PHear domain with phosphorylated AP2 mu2 148-163 | | 分子名称: | AP-2 complex subunit mu, Adaptin ear-binding coat-associated protein 1 | | 著者 | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | | 登録日 | 2019-04-18 | | 公開日 | 2019-09-04 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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6S53
 | | Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... | | 著者 | Kiss, L, Boland, A, Neuhaus, D, James, L.C. | | 登録日 | 2019-06-30 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
Nat Commun, 10, 2019
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5TXS
 | | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-15 alpha chain, ... | | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | | 登録日 | 2016-11-17 | | 公開日 | 2017-11-29 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
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6TL0
 | | Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of VPS29 with VARP 687-747 | | 分子名称: | Ankyrin repeat domain-containing protein 27, Vacuolar protein sorting-associated protein 29, ZINC ION | | 著者 | Owen, D.J, Neuhaus, D, Yang, J.-C, Crawley-Snowdon, H. | | 登録日 | 2019-11-29 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.
Nat Commun, 11, 2020
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6RH5
 | | Solution structure and 1H, 13C and 15N chemical shift assignments for NECAP1 PHear domain | | 分子名称: | Adaptin ear-binding coat-associated protein 1 | | 著者 | Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T. | | 登録日 | 2019-04-18 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
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5VZ5
 | | Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Toor, J, Rao, A.A, Salama, S, Tripathi, S, Haussler, D, Sgourakis, N.G. | | 登録日 | 2017-05-26 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5901 Å) | | 主引用文献 | A Recurrent Mutation in Anaplastic Lymphoma Kinase with Distinct Neoepitope Conformations.
Front Immunol, 9, 2018
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4JEH
 | | Crystal Structure of Munc18a and Syntaxin1 lacking N-peptide complex | | 分子名称: | Syntaxin-1A, Syntaxin-binding protein 1 | | 著者 | Colbert, K.N, Hattendorf, D.A, Weiss, T.M, Burkhardt, P, Fasshauer, D, Weis, W.I. | | 登録日 | 2013-02-27 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JEU
 | | Crystal Structure of Munc18a and Syntaxin1 with native N-terminus complex | | 分子名称: | Syntaxin-1A, Syntaxin-binding protein 1 | | 著者 | Colbert, K.N, Hattendorf, D.A, Weiss, T.M, Burkhardt, P, Fasshauer, D, Weis, W.I. | | 登録日 | 2013-02-27 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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7C2O
 | | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, R-specific carbonyl reductase, ... | | 著者 | Vinaykumar, K, KanalElamparithi, B, Chaudhury, D, Gunasekaran, K, Chadha, A. | | 登録日 | 2020-05-08 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the R-specific Carbonyl Reductase from Candida parapsilosis ATCC 7330 without DTT
To Be Published
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6CSJ
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2FB8
 | | Structure of the B-Raf kinase domain bound to SB-590885 | | 分子名称: | (1Z)-5-(2-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-PYRIDIN-4-YL-1H-IMIDAZOL-4-YL)INDAN-1-ONE OXIME, B-Raf proto-oncogene serine/threonine-protein kinase | | 著者 | Lougheed, J.C, Lee, J, Chau, D.C, Stout, T.J. | | 登録日 | 2005-12-08 | | 公開日 | 2006-12-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
Cancer Res., 66, 2006
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6TVH
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6TX2
 | | Human HPF1 | | 分子名称: | Histone PARylation factor 1, SODIUM ION | | 著者 | Suskiewicz, M.J, Ahel, I. | | 登録日 | 2020-01-13 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation.
Nature, 579, 2020
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5O7N
 | | Beta-lactamase VIM-2 in complex with (2R)-1-(2-Benzyl-3-mercaptopropanoyl)piperidine-2-carboxylic acid | | 分子名称: | (2~{R})-1-[(2~{S})-2-(phenylmethyl)-3-sulfanyl-propanoyl]piperidine-2-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase VIM-2, ... | | 著者 | Buettner, D, Kramer, J.S, Pogoryelov, D, Proschak, E. | | 登録日 | 2017-06-09 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-beta-Lactamases.
Acs Infect Dis., 4, 2018
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1MRB
 | | THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE | | 分子名称: | CADMIUM ION, CD7 METALLOTHIONEIN-2A | | 著者 | Braun, W, Arseniev, A, Schultze, P, Woergoetter, E, Wagner, G, Vasak, M, Kaegi, J.H.R, Wuthrich, K. | | 登録日 | 1990-05-14 | | 公開日 | 1991-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.
J.Mol.Biol., 201, 1988
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2MRB
 | | THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD-7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE | | 分子名称: | CADMIUM ION, CD7 METALLOTHIONEIN-2A | | 著者 | Braun, W, Arseniev, A, Schultze, P, Woergoetter, E, Wagner, G, Vasak, M, Kaegi, J.H.R, Wuthrich, K. | | 登録日 | 1990-05-14 | | 公開日 | 1991-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of rabbit liver [Cd7]metallothionein-2a in aqueous solution determined by nuclear magnetic resonance.
J.Mol.Biol., 201, 1988
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1CX2
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8A58
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6COX
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5COX
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5VS6
 | | Structure of DUB complex | | 分子名称: | ACETATE ION, GLYCEROL, N-[3-({4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl}methyl)-4-oxo-3,4-dihydroquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide, ... | | 著者 | Seo, H.-S, Dhe-Paganon, S. | | 登録日 | 2017-05-11 | | 公開日 | 2017-12-20 | | 最終更新日 | 2018-01-03 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Cell Chem Biol, 24, 2017
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