8ILH
| The crystal structure of dG(Se-Sp)-DNA:Pol X product binary complex | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOSELENOPHOSPHATE, DNA (5'-D(*CP*GP*GP*AP*TP*CP*C)-3'), MAGNESIUM ION, ... | 著者 | Qin, T, Gan, J.H, Huang, Z. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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8ILE
| The crystal structure of dGTPalphaSe-Rp:DNApre-II:Pol X substrate ternary complex | 分子名称: | DNA (5'-D(*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), MANGANESE (II) ION, Repair DNA polymerase X, ... | 著者 | Qin, T, Gan, J.H, Huang, Z. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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8ILD
| The crystal structure of native dGTP:DNApre-I:Pol X substrate ternary complex | 分子名称: | DNA (5'-D(*CP*AP*GP*GP*AP*TP*CP*CP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Qin, T, Chen, Y.Q, Gan, J.H, Huang, Z. | 登録日 | 2023-03-03 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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8ILF
| The crystal structure of dGTPalphaSe-Sp:DNApre-II:Pol X substrate ternary complex | 分子名称: | DNA (5'-D(*CP*TP*GP*GP*AP*TP*CP*CP*A)-3'), MANGANESE (II) ION, Repair DNA polymerase X, ... | 著者 | Qin, T, Zhao, Q.W, Gan, J.H, Huang, Z. | 登録日 | 2023-03-03 | 公開日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom. Int J Mol Sci, 24, 2023
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8IQD
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8IQI
| Structure of Full-Length AsfvPrimPol in Complex-Form | 分子名称: | DNA (32-MER), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Shao, Z.W, Su, S.C, Gan, J.H. | 登録日 | 2023-03-16 | 公開日 | 2023-07-26 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Structures and implications of the C962R protein of African swine fever virus. Nucleic Acids Res., 51, 2023
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8IQB
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8IQC
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8IQH
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5EN1
| Crystal structure of hnRNPA2B1 in complex with RNA | 分子名称: | Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') | 著者 | Wu, B.X, Su, S.C, Ma, J.B. | 登録日 | 2015-11-09 | 公開日 | 2016-11-09 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 Nat Commun, 2018
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8IT9
| Co-crystal structure of FTO bound to 22 | 分子名称: | 2-OXOGLUTARIC ACID, 2-[(2,6-diethyl-4-pyridin-4-yl-phenyl)amino]-6-(1,4-oxazepan-4-ylmethyl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO | 著者 | Yang, C.-G, Gan, J.H. | 登録日 | 2023-03-22 | 公開日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties. J.Med.Chem., 66, 2023
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7WWF
| Crystal structure of BioH3 from Mycolicibacterium smegmatis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Esterase | 著者 | Yang, J, Xu, Y.C, Gan, J.H, Feng, Y.J. | 登録日 | 2022-02-12 | 公開日 | 2022-07-06 | 最終更新日 | 2023-01-18 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target. Plos Pathog., 18, 2022
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7XP0
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7XP1
| Crystal structure of PmiR from Pseudomonas aeruginosa | 分子名称: | ALPHA-METHYLISOCITRIC ACID, GLYCEROL, Probable transcriptional regulator, ... | 著者 | Zhang, Y.X, Liang, H.H, Gan, J.H. | 登録日 | 2022-05-02 | 公開日 | 2023-04-12 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa. Sci Adv, 8, 2022
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7Y57
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7Y56
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5GPO
| The sensor domain structure of the zinc-responsive histidine kinase CzcS from Pseudomonas Aeruginosa | 分子名称: | SULFATE ION, Sensor protein CzcS, ZINC ION | 著者 | Wang, D, Chen, W.Z, Huang, S.Q, Liu, X.C, Hu, Q.Y, Wei, T.B, Gan, J.H, Chen, H. | 登録日 | 2016-08-03 | 公開日 | 2017-08-09 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Structural basis of Zn(II) induced metal detoxification and antibiotic resistance by histidine kinase CzcS in Pseudomonas aeruginosa PLoS Pathog., 13, 2017
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5XMA
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7VP9
| Crystal structure of human ClpP in complex with ZG111 | 分子名称: | (6S,9aS)-N-[(4-bromophenyl)methyl]-6-[(2S)-butan-2-yl]-8-(naphthalen-1-ylmethyl)-4,7-bis(oxidanylidene)-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... | 著者 | Wang, P.Y, Gan, J.H, Yang, C.-G. | 登録日 | 2021-10-15 | 公開日 | 2022-06-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.552 Å) | 主引用文献 | Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma. Cell Chem Biol, 29, 2022
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5XUN
| Crystal structure of Y145F mutant of KacT | 分子名称: | ACETATE ION, ACETYL COENZYME *A, Acetyltransferase | 著者 | Qian, H.L, Yao, Q.Q, Gan, J.H, Ou, H.Y. | 登録日 | 2017-06-23 | 公開日 | 2017-07-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification and characterization of acetyltransferase-type toxin-antitoxin locus in Klebsiella pneumoniae Mol. Microbiol., 108, 2018
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5XM9
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5ZFZ
| Crystal structure of human DUX4 homeodomains bound to A12T DNA mutant | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*TP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*AP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | 登録日 | 2018-03-07 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
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5ZFW
| Crystal structure of human DUX4 homeodomains bound to A11G DNA mutant | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*GP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*CP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | 登録日 | 2018-03-07 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
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5ZFY
| Crystal structure of human DUX4 homeodomains bound to A12C DNA mutant | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*CP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*GP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4-like protein 4 | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | 登録日 | 2018-03-07 | 公開日 | 2018-10-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
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5Z6Z
| Crystal structure of human DUX4 homeodomains bound to DNA | 分子名称: | DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4 | 著者 | Li, Y.Y, Wu, B.X, Gan, J.H. | 登録日 | 2018-01-26 | 公開日 | 2018-10-31 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structural basis for multiple gene regulation by human DUX4. Biochem. Biophys. Res. Commun., 505, 2018
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