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8U03
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BU of 8u03 by Molmil
Crystal structure of non-glycosylated 10E8-GT10.1 scaffold in complex with a human 10E8 NGS precursor (10E8-NGS-03)
分子名称: 10E8-GT10.1 epitope scaffold, 10E8-NGS-03 Fab Light Chain, 10E8-NGS-03 Fab heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8U08
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BU of 8u08 by Molmil
Crystal structure of 10E8-GT11 scaffold in complex with a human 10E8 inferred germline (10E8-iGL1)
分子名称: 10E8-GT11 epitope scaffold, 10E8-IGL1 heavy chain, 10E8-IGL1 light chain, ...
著者Irimia, A, Wilson, I.A.
登録日2023-08-28
公開日2024-06-12
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 2024
8V2E
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BU of 8v2e by Molmil
Crystal structure of B055 scaffold boost immunogen in complex with a mature 10E8 Fab
分子名称: 10E8 EPITOPE SCAFFOLD B055, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 10E8 FAB HEAVY CHAIN, ...
著者Cho, S.Y, Wilson, I.A.
登録日2023-11-22
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Nat.Immunol., 25, 2024
6CJK
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BU of 6cjk by Molmil
Anti HIV Fab 10A
分子名称: ACETATE ION, GLYCEROL, Immunoglobulin Fab heavy chain, ...
著者Hangartner, L, Ward, A.B, Wilson, I.A, Oyen, D.
登録日2018-02-26
公開日2018-08-15
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.795 Å)
主引用文献Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity, 49, 2018
5VZR
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BU of 5vzr by Molmil
Crystal Structure of MERS-CoV neutralizing antibody G4 Fab
分子名称: G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
著者Wang, N, Wrapp, D, McLellan, J.S.
登録日2017-05-29
公開日2017-08-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V8L
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BU of 5v8l by Molmil
BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3BNC117 antibody, ...
著者Lee, J.H, Ward, A.B.
登録日2017-03-22
公開日2017-05-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure.
Immunity, 46, 2017
5VYH
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BU of 5vyh by Molmil
Crystal Structure of MERS-CoV S1 N-terminal Domain
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
著者Wang, N, Wrapp, D, Pallesen, J, Ward, A.B, McLellan, J.S.
登録日2017-05-25
公開日2017-08-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VN3
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BU of 5vn3 by Molmil
Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b
分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ozorowski, G, Pallesen, J, Ward, A.B.
登録日2017-04-28
公開日2017-07-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017
5WDU
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BU of 5wdu by Molmil
HIV-1 Env BG505 SOSIP.664 H72C-H564C trimer in complex with bNAbs PGT122 Fab, 35O22 Fab and NIH45-46 scFv
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Julien, J.-P, Torrents de la Pena, A, Sanders, R.W, Wilson, I.A.
登録日2017-07-06
公開日2018-04-04
最終更新日2022-11-30
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.
Cell Rep, 20, 2017
5W9J
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BU of 5w9j by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, Spike glycoprotein
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9P
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BU of 5w9p by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, Spike glycoprotein
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9M
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BU of 5w9m by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, Spike glycoprotein
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9I
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BU of 5w9i by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ...
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9O
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BU of 5w9o by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, Spike glycoprotein
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2020-01-01
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UY3
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BU of 5uy3 by Molmil
Crystal structure of human Fab PGT144, a broadly reactive and potent HIV-1 neutralizing antibody
分子名称: Antibody PGT144 Fab heavy chain, Antibody PGT144 Fab light chain
著者Julien, J.-P, Lee, J.H, Wilson, I.A.
登録日2017-02-23
公開日2017-04-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic beta-Hairpin Structure.
Immunity, 46, 2017
5W9L
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BU of 5w9l by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, Spike glycoprotein
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9H
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BU of 5w9h by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G4 VH, ...
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9K
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BU of 5w9k by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, Spike glycoprotein
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9N
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BU of 5w9n by Molmil
MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4
分子名称: G4 VH, G4 VL, MERS S
著者Pallesen, J, Ward, A.B.
登録日2017-06-23
公開日2017-08-16
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7L90
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BU of 7l90 by Molmil
BG505 SOSIP.v5.2 N241/N289 in complex with the polyclonal Fab pAbC-8 from animal Rh.33311 (Wk26 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2 N241/N289 - gp120, ...
著者Antanasijevic, A, Sewall, L.M, Ward, A.B.
登録日2021-01-01
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
6U59
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BU of 6u59 by Molmil
HIV-1 B41 SOSIP.664 in complex with rabbit antibody 13B
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SOSIP.664 gp120,SOSIP.664 gp120, ...
著者Yang, Y.R, Ward, A.B.
登録日2019-08-27
公開日2020-01-29
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits.
J.Virol., 94, 2020
6VFK
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BU of 6vfk by Molmil
De novo designed tetrahedral nanoparticle T33_dn10 displaying 4 copies of BG505-SOSIP trimer on the surface
分子名称: BG505-SOSIP-T33_dn10A, T33_dn10B
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-07-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
6VFL
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BU of 6vfl by Molmil
BG505-SOSIP model reconstructed by subparticle extraction and refinement from a tetrahedral nanoparticle T33_dn10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIPv5.2(7S) - gp120, ...
著者Antanasijevic, A, Ward, A.B.
登録日2020-01-05
公開日2020-07-22
最終更新日2020-08-26
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens.
Plos Pathog., 16, 2020
7L7T
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BU of 7l7t by Molmil
BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ...
著者Antanasijevic, A, Cannac, F, Sewall, L.M, Ward, A.B.
登録日2020-12-30
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
7L8C
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BU of 7l8c by Molmil
BG505 SOSIP MD39 in complex with the polyclonal Fab pAbC-3 from animal Rh.33104 (Wk26 time point)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP MD39 - gp120, ...
著者Antanasijevic, A, Sewall, L.M, Perrett, H.R, Ward, A.B.
登録日2020-12-31
公開日2021-08-04
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021

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件を2024-06-12に公開中

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