7PW8
| Human SMG1-8-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW7
| Human SMG1-9 kinase complex bound to a SMG1 inhibitor | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW6
| Human SMG1-8-9 kinase complex bound to a SMG1 inhibitor - SMG1 body | 分子名称: | 1-[4-[4-[2-[[4-chloranyl-3-(diethylsulfamoyl)phenyl]amino]pyrimidin-4-yl]pyridin-2-yl]phenyl]-3-methyl-urea, INOSITOL HEXAKISPHOSPHATE, Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1,Serine/threonine-protein kinase SMG1 | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW9
| Human SMG1-9 kinase complex bound to AMPPNP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... | 著者 | Langer, L.M, Conti, E. | 登録日 | 2021-10-06 | 公開日 | 2021-12-01 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10, 2021
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7PW5
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1RK8
| Structure of the cytosolic protein PYM bound to the Mago-Y14 core of the exon junction complex | 分子名称: | CALCIUM ION, CG8781-PA protein, Mago nashi protein, ... | 著者 | Bono, F, Ebert, J, Guettler, T, Izaurralde, E, Conti, E. | 登録日 | 2003-11-21 | 公開日 | 2004-04-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular insights into the interaction of PYM with
the Mago-Y14 core of the exon junction complex EMBO Rep., 5, 2004
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2VNU
| Crystal structure of Sc Rrp44 | 分子名称: | 5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP)-3', EXOSOME COMPLEX EXONUCLEASE RRP44, MAGNESIUM ION, ... | 著者 | Lorentzen, E, Basquin, J, Conti, E. | 登録日 | 2008-02-07 | 公開日 | 2008-04-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Active Subunit of the Yeast Exosome Core, Rrp44: Diverse Modes of Substrate Recruitment in the Rnase II Nuclease Family Mol.Cell, 29, 2008
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2VXG
| Crystal structure of the conserved C-terminal region of Ge-1 | 分子名称: | CG6181-PA, ISOFORM A | 著者 | Jinek, M, Eulalio, A, Lingel, A, Helms, S, Conti, E, Izaurralde, E. | 登録日 | 2008-07-04 | 公開日 | 2008-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The C-Terminal Region of Ge-1 Presents Conserved Structural Features Required for P-Body Localization. RNA, 14, 2008
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2WP8
| yeast rrp44 nuclease | 分子名称: | CHLORIDE ION, EXOSOME COMPLEX COMPONENT RRP45, EXOSOME COMPLEX COMPONENT SKI6, ... | 著者 | Basquin, J, Bonneau, F, Ebert, J, Lorentzen, E, Conti, E. | 登録日 | 2009-08-03 | 公開日 | 2009-11-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Yeast Exosome Functions as a Macromolecular Cage to Channel RNA Substrates for Degradation. Cell(Cambridge,Mass.), 139, 2009
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5C0Y
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5C0W
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5C0X
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5AJD
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5AIE
| Not4 ring domain in complex with Ubc4 | 分子名称: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 4, UBIQUITIN-CONJUGATING ENZYME E2 4, ZINC ION | 著者 | Bhaskar, V, Basquin, J, Conti, E. | 登録日 | 2015-02-12 | 公開日 | 2015-04-29 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Architecture of the Ubiquitylation Module of the Yeast Ccr4-not Complex. Structure, 23, 2015
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2XGJ
| Structure of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT RNA HELICASE DOB1, RNA (5'-(*AP*AP*AP*AP*A)-3') | 著者 | Weir, J.R, Bonneau, F, Hentschel, J, Conti, E. | 登録日 | 2010-06-04 | 公開日 | 2010-06-23 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Analysis Reveals the Characteristic Features of Mtr4, a Dexh Helicase Involved in Nuclear RNA Processing and Surveillance. Proc.Natl.Acad.Sci.USA, 107, 2010
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2XZL
| Upf1-RNA complex | 分子名称: | 5- R(*UP*UP*UP*UP*UP*UP*UP*UP*U) -3, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HELICASE NAM7, ... | 著者 | Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E. | 登録日 | 2010-11-26 | 公開日 | 2011-03-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2. Mol.Cell, 41, 2011
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8BFJ
| CNOT11-GGNBP2 complex | 分子名称: | 1,2-ETHANEDIOL, CCR4-NOT transcription complex subunit 11, Gametogenetin-binding protein 2 | 著者 | Basquin, J, Ozgur, S, Conti, E. | 登録日 | 2022-10-26 | 公開日 | 2022-12-28 | 最終更新日 | 2023-02-15 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions. Cell Rep, 42, 2023
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8BFH
| CNOT11 | 分子名称: | CCR4-NOT transcription complex subunit 11 | 著者 | Basquin, J, Ozgur, S, Conti, E. | 登録日 | 2022-10-26 | 公開日 | 2022-12-28 | 最終更新日 | 2023-02-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions. Cell Rep, 42, 2023
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8BFI
| human CNOT1-CNOT10-CNOT11 module | 分子名称: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | 著者 | Basquin, J, Ozgur, S, Conti, E. | 登録日 | 2022-10-26 | 公開日 | 2022-12-28 | 最終更新日 | 2023-02-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions. Cell Rep, 42, 2023
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2XZP
| Upf1 helicase | 分子名称: | GLYCEROL, MALONATE ION, REGULATOR OF NONSENSE TRANSCRIPTS 1 | 著者 | Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E. | 登録日 | 2010-11-26 | 公開日 | 2011-03-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2. Mol.Cell, 41, 2011
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2XZO
| Upf1 helicase - RNA complex | 分子名称: | 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E. | 登録日 | 2010-11-26 | 公開日 | 2011-03-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2. Mol.Cell, 41, 2011
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5MC6
| Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R. | 登録日 | 2016-11-09 | 公開日 | 2017-01-18 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex. Science, 354, 2016
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1OF5
| Crystal structure of Mex67-Mtr2 | 分子名称: | MERCURY (II) ION, MRNA EXPORT FACTOR MEX67, MRNA TRANSPORT REGULATOR MTR2 | 著者 | Fribourg, S, Conti, E. | 登録日 | 2003-04-08 | 公開日 | 2003-07-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural similarity in the absence of sequence homology of the messenger RNA export factors Mtr2 and p15. EMBO Rep., 4, 2003
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1OL6
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1OL7
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