4IFD

Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA

Summary for 4IFD

Entry DOI	10.2210/pdb4ifd/pdb
Descriptor	Exosome complex component RRP45, Exosome complex exonuclease DIS3, Exosome complex exonuclease RRP6, ... (18 entities in total)
Functional Keywords	exosome, rna, rrp44, dis3, pin, rrp6, exonuclease, endonuclease, hydrolase, nuclease, ribonuclease, rna processing, hydrolase-rna complex, hydrolase/rna
Biological source	Saccharomyces cerevisiae (Baker's yeast) More
Cellular location	Cytoplasm : Q05636 Q08162 P46948 P25359 P53256 Q12277 P48240 Q08285 P38792 P53859 Nucleus, nucleolus : Q12149
Total number of polymer chains	12
Total formula weight	438162.46
Authors	Makino, D.L.,Conti, E. (deposition date: 2012-12-14, release date: 2013-02-06, Last modification date: 2023-11-08)
Primary citation	Makino, D.L.,Baumgartner, M.,Conti, E. Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex. Nature, 495:70-75, 2013 Cited by PubMed: 23376952 DOI: 10.1038/nature11870 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.805 Å)

Structure validation